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InventoryRef 8916505/07/2012

ARTEMISINIC ACID

Artemisinic Acid is the organic compound

ARTEMISINIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 80286-58-4
CAS 80286-58-4PubChem CID 10922465

Artemisinic Acid

(+)-artemisinic acid is a monocarboxylic acid that is prop-2-enoic acid which is substituted at position 2 by a 4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl group (the 1S,4R,4aS,8aR diastereoisomer). It is a sesquiterpenoid precursor of artemisinin, obtained from sweet wormwood, Artemisia annua. It has a role as a metabolite. It is a member of octahydronaphthalenes, a monocarboxylic acid, a sesquiterpenoid and a carbobicyclic compound. It is functionally related to a (+)-artemisinic alcohol. It is a conjugate acid of a (+)-artemisinate. — ChEBI

IUPAC name
2-[(1R,4R,4aS,8aR)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl]prop-2-enoic acid
Molecular formula
C15H22O2
Molecular weight
234.33 g/mol
Exact mass
234.161979940 Da
XLogP3
3.8
Topological polar surface area
37.3 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
4

Also known as

Artemisic acid(+)-artemisinic acidSINGLEEX ARTEMISINIC ACID53N99527G7CHEBI:637492-((1R,4R,4aS,8aR)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl)prop-2-enoic acid1-Naphthaleneacetic acid, 1,2,3,4,4a,5,6,8a-octahydro-4,7-dimethyl-alpha-methylene-, (1R-(1alpha,4beta,4abeta,8abeta))-RefChem:114255
16 more reported names
617-040-5Arteannuic acid2-((1r,4r,4as,8ar)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl)acrylic acid1-NAPHTHALENEACETIC ACID, 1,2,3,4,4A,5,6,8A-OCTAHYDRO-4,7-DIMETHYL-.ALPHA.-METHYLENE-, (1R,4R,4AS,8AR)-QING HAU ACIDArtemisinicacidArtemisinic-acidUNII-53N99527G74,11(13)-Cadinadien-12-oic acid4,11(13)-Amorphadien-12-oic acidQING HAO ACIDQing Hao acid; Artemisinic acid; Arteannuic acidARTEMISININIC ACIDEC 617-040-5PLQMEXSCSAIXGB-SAXRGWBVSA-NHY-N1984
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ARTEMISINIC ACID

INCI name

ARTEMISINIC ACID

Description

Artemisinic Acid is the organic compound

Record provenance

Inventory reference
89165
Imported identity
ARTEMISINIC ACID
Source update
05/07/2012
European Commission CosIng source notes
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Key data

CAS
80286-58-4
EC
—
Restriction
—
Function
—

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#2379 · ARTEMISINIC ACID

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How ARTEMISINIC ACID appears in the CosIng inventory

The CosIng inventory lists ARTEMISINIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

Regulatory conditions, if any, come from Annex II–VI records and should be checked before use in a formulation.

Frequently asked questions

ARTEMISINIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

CAS 80286-58-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for ARTEMISINIC ACID

This page reproduces the CosIng inventory entry for ARTEMISINIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ARTEMISINIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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