Is MASLINIC ACID safe to use in EU cosmetics?

MASLINIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 4373-41-5?

CAS 4373-41-5 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains MASLINIC ACID?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 8670615/10/2010

MASLINIC ACID

Olean-12-en-28-oic acid, 2,3-dihydroxy-,

MASLINIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

INCI Checker Compare all markets Search similar

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Markets and their official sources Search every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 4373-41-5

CAS 4373-41-5PubChem CID 73659

Maslinic Acid

Maslinic acid is a pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer). It is isolated from Olea europaea and Salvia canariensis and exhibits anti-inflammatory, antioxidant and antineoplastic activity. It has a role as an antioxidant, an antineoplastic agent, an anti-inflammatory agent and a plant metabolite. It is a pentacyclic triterpenoid and a dihydroxy monocarboxylic acid. It derives from a hydride of an oleanane. — ChEBI

IUPAC name: (4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid

Molecular formula: C30H48O4
Molecular weight: 472.7 g/mol
Exact mass: 472.35526001 Da
XLogP3: 6.5
Topological polar surface area: 77.8 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 9

Also known as

Crategolic acidCrataegolic acidMaslic acidMasilinic acid2alpha-hydroxyoleanolic acidE233J88OHQ2alpha,3beta-dihydroxyurs-12-en-29-oic acidCHEBI:66682

16 more reported names

2-hydroxyoleanolic acidOlean-12-en-28-oic acid, 2,3-dihydroxy-, (2alpha,3beta)-RefChem:41765(2alpha, 3beta)-2,3-dihydroxyolean-12-en-28-oic acid(2beta, 3alpha)-2,3-dihydroxyolean-12-en-28-oic acid(2alpha, 3beta)-2,3-dihydroxy-olean-12-en-28-oic acidolean-12-en-28-oic acid, 2,3-dihydroxy-, (2alpha, 3beta)-610-137-32alpha,3beta-dihydroxyolean-12-en-28-oic acidMaslinicacidOlean-12-en-28-oic acid, 2,3-dihydroxy-, (2.alpha.,3.beta.)-UNII-E233J88OHQmaslinatic acidMaslinic-acidHSDB 8099Maslinic acid (Standard)

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:66682
ChEMBL:CHEMBL201515
EPA DTXSID:DTXSID30905074
PubMed:26513295
PubMed:24480359
PubMed:24406786
PubMed:23122121
PubMed:23003682
PubMed:22860449
PubMed:22846081
PubMed:22816768
PubMed:22799301
PubMed:22760979
PubMed:22685487
PubMed:22574636

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for MASLINIC ACID

INCI name

MASLINIC ACID

Description

Olean-12-en-28-oic acid, 2,3-dihydroxy-,

Record provenance

Inventory reference: 86706
Imported identity: MASLINIC ACID
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for MASLINIC ACID

Browse

Browse EU annexes

Explore Annex II–VI to see which substances are prohibited, restricted or permitted under specific conditions.

Search annex entries

Search the annex database for entries matching MASLINIC ACID or related substances.

Key data

CAS

4373-41-5

—

Restriction

—

Function

ANTIOXIDANT: Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#16034 · MASLINIC ACID

Ingredients with overlapping formulation functions

MANGANESE GLYCINATEANTIOXIDANT, SKIN CONDITIONING

MANGANESE PYRIDOXAL 5-PHOSPHATEANTIOXIDANT, SKIN CONDITIONING

MANGANESE QUINOLYLMETHYLAMINOETHYL PYRIDINYLTRIAZACYCLODODECANEANTIOXIDANT

MARTYNOSIDEANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

MATRICARIA MARITIMA EXTRACTANTIOXIDANT, SKIN CONDITIONING

MATRINEANTIOXIDANT, SKIN CONDITIONING

MATTEUCCIA STRUTHIOPTERIS EXTRACTANTIOXIDANT, SKIN CONDITIONING

MATTHIOLA INCANA CALLUS CULTURE EXTRACTANTIOXIDANT, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How MASLINIC ACID appears in the CosIng inventory

The CosIng inventory lists MASLINIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

MASLINIC ACID is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

MASLINIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, MASLINIC ACID carries the following function designation(s):

CAS 4373-41-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

View CAS records

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Open INCI Checker

Source note for MASLINIC ACID

This page reproduces the CosIng inventory entry for MASLINIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research MASLINIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sources View updates

Tools & next steps

Check your formula

Scan a full INCI list to detect MASLINIC ACID and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to MASLINIC ACID, its identifiers or nearby name variants.