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InventoryRef 8640215/10/2010

INDOCYANINE GREEN

sodium 2-[7-[3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolin-2-ylidene]hepta-1,3,5-trien-1-yl]-3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium

INDOCYANINE GREEN is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 3599-32-4
CAS 3599-32-4PubChem CID 5282412

Indocyanine Green

Indocyanine green is a cyanine dye, a benzoindole and a 1,1-diunsubstituted alkanesulfonate. ChEBI

IUPAC name
sodium 4-[(2Z)-2-[(2E,4E,6E)-7-[1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-3-ium-2-yl]hepta-2,4,6-trienylidene]-1,1-dimethylbenzo[e]indol-3-yl]butane-1-sulfonate
Molecular formula
C43H47N2NaO6S2
Molecular weight
775.0 g/mol
Exact mass
774.27732385 Da
Topological polar surface area
137.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
7
Covalent units
2
Defined stereocentres
0

Also known as

WofaverdinCardiogreenFox GreenIC-GreenUjoviridinCardio-GreenHWD Indocyanine GreenSpy agent green
16 more reported names
IR 125NK 1611IX6J1063HVCHEBI:31696UjoveridinVofaverdinVophaverdinCardio GreenGreen, IndocyanineSPY Elite KitSPY Lymphatics KitSPY-MIS KitSPY-PHI KitRefChem:55397PINPOINT Lymphatics KitSPY AGENT GREEN KIT
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for INDOCYANINE GREEN

INCI name

INDOCYANINE GREEN

Description

sodium 2-[7-[3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolin-2-ylidene]hepta-1,3,5-trien-1-yl]-3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium

Record provenance

Inventory reference
86402
Imported identity
INDOCYANINE GREEN
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
Function
UV ABSORBER
Protecting the cosmetic product from the effects of UV-light.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How INDOCYANINE GREEN appears in the CosIng inventory

The CosIng inventory lists INDOCYANINE GREEN as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

INDOCYANINE GREEN is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

INDOCYANINE GREEN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, INDOCYANINE GREEN carries the following function designation(s):

CAS 3599-32-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for INDOCYANINE GREEN

This page reproduces the CosIng inventory entry for INDOCYANINE GREEN from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research INDOCYANINE GREEN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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