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CAS 157283-66-4 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 8569603/08/2011

ISOPROPYL CLOPROSTENATE

Isopropyl Cloprostenate is a synthetic analogue of a prostaglandin.

ISOPROPYL CLOPROSTENATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 157283-66-4

CAS 157283-66-4PubChem CID 59938277

Isopropyl Cloprostenate

IUPAC name: propan-2-yl (Z)-7-[(1R,2R,3R,5S)-2-[(E,3R)-4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate

Molecular formula: C25H35ClO6
Molecular weight: 467.0 g/mol
Exact mass: 466.2122165 Da
XLogP3: 3.8
Topological polar surface area: 96.2 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 6
Covalent units: 1
Defined stereocentres: 5

Also known as

Cloprostenol isopropyl esterIsopropyl cloprostenolUNII-765298537GCPG-6112955-Heptenoic acid, 7-((1R,2R,3R,5S)-2-((1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl)-3,5-dihydroxycyclopentyl)-, 1-methylethyl ester, (5Z)-5-Heptenoic acid, 7-((1R,2R,3R,5S)-2-((1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl)-3,5-dihydroxycyclopentyl)-, 1-methylethyl ester, (5Z)-CPG-6112-955-Heptenoic acid, 7-(2-(4-(3-chlorophenoxy)-3-hydroxy-1-butenyl)-3,5-dihydroxycyclopentyl)-, 1-methylethyl ester, (1R-(1alpha(Z),2beta(1E,3R*),3alpha,5alpha))-

16 more reported names

5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, 1-methylethyl ester, (5Z)-RefChem:149814ISOPROPYL CLOPROSTENATE [INCI]5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-, 1-methylethyl ester, (5Z)-(9CI)682-025-2(+)-Cloprostenol isopropyl esterisopropyl (Z)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate(+)-16-m-chlorophenoxy tetranor Prostaglandin F2alpha isopropyl esterISOPROPYL CLOPROSTENATC25H35ClO6D-cloprostenol isopropyl ester(+)-CloprostenolisopropylesterMSK2978CPG 6112-95HY-100571CS-0019712

Open full PubChem record PubChem annotations 3D structure image

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ISOPROPYL CLOPROSTENATE

INCI name

ISOPROPYL CLOPROSTENATE

Description

Isopropyl Cloprostenate is a synthetic analogue of a prostaglandin.

Record provenance

Inventory reference: 85696
Imported identity: ISOPROPYL CLOPROSTENATE
Source update: 03/08/2011

European Commission CosIng source notes

Annex records for ISOPROPYL CLOPROSTENATE

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Key data

CAS

157283-66-4

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Restriction

—

Function

HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#13840 · ISOPROPYL CLOPROSTENATE

Ingredients with overlapping formulation functions

ISOPHORONE DIAMINE SESQUIMALEATEHAIR CONDITIONING

ISOPOLYGLYCERYL-3 DIMETHICONECLEANSING, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTA…

ISOPOLYGLYCERYL-3 DIMETHICONOLCLEANSING, HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANS…

ISOPROCURCUMENOLHAIR CONDITIONING; SKIN PROTECTING; SKIN CONDITIONING - MISCELLANEOUS

ISOPROPYL PELARGONATEHAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT

ISOPROPYLBENZYL BUTYLNORBERBERINE IODIDEANTI-SEBORRHEIC, ANTIMICROBIAL, HAIR CONDITIONING

ISOSTEARAMIDOETHYL ISOSTEARYLMETHYLIMIDAZOLINIUM METHOSULFATEHAIR CONDITIONING

ISOSTEARAMIDOPROPYL BETAINEANTISTATIC, CLEANSING, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - F…

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ISOPROPYL CLOPROSTENATE appears in the CosIng inventory

The CosIng inventory lists ISOPROPYL CLOPROSTENATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ISOPROPYL CLOPROSTENATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ISOPROPYL CLOPROSTENATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ISOPROPYL CLOPROSTENATE carries the following function designation(s):

HAIR CONDITIONING

CAS 157283-66-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ISOPROPYL CLOPROSTENATE

This page reproduces the CosIng inventory entry for ISOPROPYL CLOPROSTENATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ISOPROPYL CLOPROSTENATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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