What does the restriction note for HUMAN PLACENTAL ENZYMES mean?

The restriction field for HUMAN PLACENTAL ENZYMES reads: II/416. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

How do I check if my formula contains HUMAN PLACENTAL ENZYMES?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 8464015/10/2010

HUMAN PLACENTAL ENZYMES

Human Placental Enzymes are the enzymes derived from human placentas obtained from normal afterbirth

HUMAN PLACENTAL ENZYMES is linked to 1 EU annex record on this page. Inventory note: II/416.

INCI Checker Compare all markets Search similar

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

Compare markets

Swipe or scroll horizontally to see every column.

Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Exact external identity check

not_found

No complete-name PubChem match was verified. The material may be a mixture, trade-style INCI identity or be indexed under another identifier; this result must not be read as proof that no related chemistry exists.

Exact CosIng INCI name equals a PubChem synonym · Checked 2026-08-31

Inventory details for HUMAN PLACENTAL ENZYMES

INCI name

HUMAN PLACENTAL ENZYMES

Description

Human Placental Enzymes are the enzymes derived from human placentas obtained from normal afterbirth

Record provenance

Inventory reference: 84640
Imported identity: HUMAN PLACENTAL ENZYMES
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for HUMAN PLACENTAL ENZYMES

Annex II Restriction reference

Entry 416

Cells, tissues or products of human origin

Key data

CAS

—

The CosIng inventory records no CAS number for this ingredient. That is the absence of an identifier in the source, not a finding about the substance.

—

Restriction

II/416

Function

HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#12263 · HUMAN PLACENTAL ENZYMES

Ingredients with overlapping formulation functions

HUMAN HAIR FOLLICLE MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACTHAIR CONDITIONING; SKIN CONDITIONING - MISCELLANEOUS

HUMAN HAIR FOLLICLE STEM CELL CONDITIONED MEDIAHAIR CONDITIONING; SKIN CONDITIONING - HUMECTANT

HUMAN HAIR KERATINHAIR CONDITIONING, SKIN CONDITIONING

HUMAN MONONUCLEAR CELL INDUCED PLURIPOTENT CELL CULTURE CONDITIONED MEDIAHAIR CONDITIONING; EYELASH CONDITIONING; SKIN CONDITIONING - MISCELLANEOUS

HUMAN PLACENTAL LIPIDSHAIR CONDITIONING, SKIN CONDITIONING

HUMAN PLACENTAL PROTEINHAIR CONDITIONING, SKIN CONDITIONING

HUMAN UMBILICAL MESENCHYMAL STEM CELL VESICLESANTIOXIDANT; ASTRINGENT; HAIR CONDITIONING; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT; SKIN CO…

HUMIC SHALE EXTRACTANTIOXIDANT, HAIR CONDITIONING, SKIN CONDITIONING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How HUMAN PLACENTAL ENZYMES appears in the CosIng inventory

The CosIng inventory lists HUMAN PLACENTAL ENZYMES as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HUMAN PLACENTAL ENZYMES is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HUMAN PLACENTAL ENZYMES appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for HUMAN PLACENTAL ENZYMES reads: "II/416". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, HUMAN PLACENTAL ENZYMES carries the following function designation(s):

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Open INCI Checker

Source note for HUMAN PLACENTAL ENZYMES

This page combines the CosIng inventory entry for HUMAN PLACENTAL ENZYMES with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research HUMAN PLACENTAL ENZYMES and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sources View updates

Tools & next steps

Check your formula

Scan a full INCI list to detect HUMAN PLACENTAL ENZYMES and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to HUMAN PLACENTAL ENZYMES, its identifiers or nearby name variants.