
Vitamin D3
Calciol is a hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D3, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone. It has a role as a geroprotector and a human metabolite. It is a steroid hormone, a secondary alcohol, a seco-cholestane, a hydroxy seco-steroid and a member of D3 vitamins. — ChEBI
- IUPAC name
- (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol
- Molecular formula
- C27H44O
- Molecular weight
- 384.6 g/mol
- Exact mass
- 384.339216023 Da
- XLogP3
- 7.9
- Topological polar surface area
- 20.2 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 1
- Covalent units
- 1
- Defined stereocentres
- 5
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:28940
- ChEMBL:CHEMBL1042
- EPA DTXSID:DTXSID6026294
- PubMed:40633737
- PubMed:39671242
- PubMed:38588969
- PubMed:38191086
- PubMed:38081571
- PubMed:37244046
- PubMed:36813254
- PubMed:36745886
- PubMed:36603807
- PubMed:36066700
- PubMed:35395231
- PubMed:34051273
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.