What does the restriction note for CAPTAN mean?

The restriction field for CAPTAN reads: II/370. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 133-06-2?

CAS 133-06-2 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains CAPTAN?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 8450015/10/2010

CAPTAN

CAPTAN is linked to 1 EU annex record on this page. Inventory note: II/370.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Evidence linked Prohibited Open this evidence	1	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Prohibited Open this evidence	1	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Evidence linked Prohibited Open this evidence	1	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 133-06-2

CAS 133-06-2PubChem CID 8606

Captan

Captan is a dicarboximide that is 3a,4,7,7a-tetrahydrophthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethyl group. A non-systemic fungicide introduced in the 1950s, it is widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops. It has a role as an antifungal agrochemical. It is a member of isoindoles, an organosulfur compound, an organochlorine compound and a phthalimide fungicide. — ChEBI

IUPAC name: 2-(trichloromethylsulfanyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione

Molecular formula: C9H8Cl3NO2S
Molecular weight: 300.6 g/mol
Exact mass: 298.934133 Da
XLogP3: 2.4
Topological polar surface area: 62.7 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

AacaptanOrthocideMerpanVondcaptanAmercideCaptaneMalipurNeracid

16 more reported names

CaptafCaptexKaptanOrthocide 406TrimegolVancide 89VanicideBangtonCaptabHexacapOsocideUgecapStauffer captanLe captaneVangard KOrthocide 50

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:34608
ChEMBL:CHEMBL388676
EPA DTXSID:DTXSID9020243
PubMed:36842454
PubMed:35395341
PubMed:34303901
PubMed:32949729
PubMed:32870474
PubMed:32745781
PubMed:32736067
PubMed:32194361
PubMed:31558096
PubMed:29950287
PubMed:29228274
PubMed:25622337

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CAPTAN

INCI name

CAPTAN

Record provenance

Inventory reference: 84500
Imported identity: CAPTAN
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for CAPTAN

Annex II Restriction reference

Entry 370

captan (ISO); 1,2,3,6-tetrahydro-N-(trichloromethylthio)phthalimide

CAS: 133-06-2

EC: 205-087-0

Key data

CAS

133-06-2

205-087-0

Restriction

II/370

Function

ANTIMICROBIAL: Preventing and/or slowing down microbial growth.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#5443 · CAPTAN

Ingredients with overlapping formulation functions

CAPRYLOYL TETRAPEPTIDE-60 NORLEUCYL TYROSYL D-METHIONINEANTI-SEBUM, ANTIMICROBIAL, ANTIOXIDANT, SKIN CONDITIONING

CAPRYLYL GLYCOL LINSEEDATEANTIMICROBIAL

CAPSICUM ANNUUM FRUIT EXTRACTANTI-SEBORRHEIC, ANTIMICROBIAL, ANTIOXIDANT, ASTRINGENT, HAIR CONDITIONING, SKIN PROTECTING

CAPSICUM CHINENSE FRUIT EXTRACTANTIMICROBIAL, ANTIOXIDANT, ASTRINGENT

CARDIOSPERMUM HALICACABUM SEED EXTRACTANTI-SEBORRHEIC, ANTI-SEBUM, ANTIMICROBIAL, SKIN CONDITIONING

CARPINUS LAXIFLORA STEM EXTRACTANTIMICROBIAL, ANTIOXIDANT, ASTRINGENT, SKIN CONDITIONING - EMOLLIENT

CARPINUS TSCHONOSKII LEAF EXTRACTANTI-SEBORRHEIC, ANTIMICROBIAL, HAIR CONDITIONING, SKIN CONDITIONING

CARTHAMUS TINCTORIUS CALLUS EXTRACTANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How CAPTAN appears in the CosIng inventory

The CosIng inventory lists CAPTAN as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CAPTAN is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CAPTAN appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for CAPTAN reads: "II/370". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, CAPTAN carries the following function designation(s):

ANTIMICROBIAL

CAS 133-06-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for CAPTAN

This page combines the CosIng inventory entry for CAPTAN with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research CAPTAN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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