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InventoryRef 8388915/10/2010

DECURSINOL

2H, 6H-Benzo[1,2-b:5,4-b']Dipyran-2-one, 7,8-Dihydro-7-Hydroxy-8,8-Dimethyl

DECURSINOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 23458-02-8
CAS 23458-02-8PubChem CID 442127

(+)-Decursinol

Decursinol is an organic heterotricyclic compound that is 7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-2-one substituted by a beta-hydroxy group at position 7 and two methyl groups at position 8. It is isolated from the roots of Angelica gigas and has been found to possess significant inhibitory activity against acetylcholinesterase enzyme (EC 3.1.1.7). It has a role as a metabolite, an analgesic, an antineoplastic agent and an EC 3.1.1.7 (acetylcholinesterase) inhibitor. It is a delta-lactone, an organic heterotricyclic compound, a secondary alcohol and a cyclic ether. ChEBI

IUPAC name
(3S)-3-hydroxy-2,2-dimethyl-3,4-dihydropyrano[3,2-g]chromen-8-one
Molecular formula
C14H14O4
Molecular weight
246.26 g/mol
Exact mass
246.08920892 Da
XLogP3
1.9
Topological polar surface area
55.8 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
1

Also known as

DecursinolSmyrinolSmirinoSFE decursinolUBI4YB704BCHEBI:43542H,6H-Benzo(1,2-b:5,4-b')dipyran-2-one, 7,8-dihydro-7-hydroxy-8,8-dimethyl-, (S)-2H,6H-Benzo(1,2-b:5,4-b')dipyran-2-one, 7,8-dihydro-7-hydroxy-8,8-dimethyl-, (S)-(+)-
16 more reported names
(3S)-3-hydroxy-2,2-dimethyl-3,4-dihydropyrano(3,2-g)chromen-8-oneRefChem:131338(S)-(+)-decursinol(S)-7-hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-2-one(7S)-7-hydroxy-8,8-dimethyl-2H,6H,7H,8H-pyrano[3,2-g]chromen-2-one(S)-7-hydroxy-8,8-dimethyl-7,8-dihydropyrano[3,2-g]chromen-2(6H)-one(7S)-7,8-dihydro-7-hydroxy-8,8-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-oneDecursinol [INCI]UNII-UBI4YB704B(S)-7-Hydroxy-8,8-dimethyl-7,8-dihydropyrano(3,2-g)chromen-2(6H)-oneDecursinol (Standard)(+)-3'S-decursinolHY-N4109RBGXFQDFSVDZUIW-LBPRGKRZSA-NGLXC-03628HMS2192M06
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DECURSINOL

INCI name

DECURSINOL

Description

2H, 6H-Benzo[1,2-b:5,4-b']Dipyran-2-one, 7,8-Dihydro-7-Hydroxy-8,8-Dimethyl

Record provenance

Inventory reference
83889
Imported identity
DECURSINOL
Source update
15/10/2010
European Commission CosIng source notes

Key data

EC
Restriction
Function
ANTIOXIDANT
Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How DECURSINOL appears in the CosIng inventory

The CosIng inventory lists DECURSINOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DECURSINOL is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DECURSINOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, DECURSINOL carries the following function designation(s):

CAS 23458-02-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for DECURSINOL

This page reproduces the CosIng inventory entry for DECURSINOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research DECURSINOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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