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InventoryRef 8380115/10/2010

PICEATANNOL

1,2-Benzenediol, 4-[(1E)-2-(3,5-Dihydroxyphenyl)Ethenyl]-; trans-3,3',4,5'-Tetrahydroxystilbene

PICEATANNOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 10083-24-6
CAS 10083-24-6PubChem CID 667639

Piceatannol

Piceatannol is a stilbenol that is trans-stilbene in which one of the phenyl groups is substituted by hydroxy groups at positions 3 and 4, while the other phenyl group is substituted by hydroxy groups at positions 3 and 5. It has a role as a geroprotector, a hypoglycemic agent, an antineoplastic agent, a protein kinase inhibitor, a tyrosine kinase inhibitor, an apoptosis inducer and a plant metabolite. It is a polyphenol, a member of catechols, a member of resorcinols and a stilbenol. It derives from a hydride of a trans-stilbene. — ChEBI

IUPAC name
4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol
Molecular formula
C14H12O4
Molecular weight
244.24 g/mol
Exact mass
244.07355886 Da
XLogP3
2.9
Topological polar surface area
80.9 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

trans-Piceatannol3-Hydroxyresveratol(E)-PiceatannolAstringenin3,3',4'5-Tetrahydroxystilbene3,4,3',5'-tetrahydroxy-trans-stilbene4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol3,3',4,5'-Tetrahydroxy-trans-stilbene
16 more reported names
6KS3LS0D4FNSC-365798NSC-622471trans-3,3',4,5'-TetrahydroxystilbeneJ61.264BCHEBI:288143,3',4,5'-STILBENETETROL, (E)-4-((E)-2-(3,5-DIHYDROXYPHENYL)ETHENYL)BENZENE-1,2-DIOL4-((E)-2-(3,5-DIHYDROXYPHENYL)VINYL)-1,2-BENZENEDIOL4-((E)-2-(3,5-dihydroxyphenyl)vinyl)benzene-1,2-diol4-((1E)-2-(3,5-dihydroxyphenyl)ethenyl)benzene-1,2-diol4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diolRefChem:44580(E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol3,5,3',4'-Tetrahydroxystilbene3,3',4,5'-Tetrahydroxystilbene
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:28814

piceatannol

A stilbenol that is trans-stilbene in which one of the phenyl groups is substituted by hydroxy groups at positions 3 and 4, while the other phenyl group is substituted by hydroxy groups at positions 3 and 5.

Formula
C14H12O4
Average mass
244.246 g/mol
Monoisotopic mass
244.07356 Da
Formal charge
0
  • resorcinols — is a (CHEBI:33572)
  • catechols — is a (CHEBI:33566)
  • polyphenol — is a (CHEBI:26195)
  • stilbenol — is a (CHEBI:36027)
  • geroprotector — has role (CHEBI:176497)
  • antineoplastic agent — has role (CHEBI:35610)
  • plant metabolite — has role (CHEBI:76924)
  • hypoglycemic agent — has role (CHEBI:35526)
  • apoptosis inducer — has role (CHEBI:68495)
  • protein kinase inhibitor — has role (CHEBI:37699)
  • tyrosine kinase inhibitor — has role (CHEBI:38637)
  • trans-stilbene — has parent hydride (CHEBI:36007)
  • geroprotector — has role (CHEBI:176497)
  • antineoplastic agent — has role (CHEBI:35610)
  • plant metabolite — has role (CHEBI:76924)
  • hypoglycemic agent — has role (CHEBI:35526)
  • apoptosis inducer — has role (CHEBI:68495)
  • protein kinase inhibitor — has role (CHEBI:37699)
  • tyrosine kinase inhibitor — has role (CHEBI:38637)
  • resorcinols — is a (CHEBI:33572)
  • catechols — is a (CHEBI:33566)
  • polyphenol — is a (CHEBI:26195)
  • stilbenol — is a (CHEBI:36027)
Additional curated names
4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol3,3',4'5-Tetrahydroxystilbene3,5,3',4'-tetrahydroxystilbene3-hydroxyresveratol4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diolPiceatannol
Cross-references from this source
  • CAS: 10083-24-6 — ChemIDplus
  • CAS: 10083-24-6 — KEGG COMPOUND
  • REGISTRY_NUMBER: 1879860 — Reaxys
  • REGISTRY_NUMBER: 1879860 — Beilstein
  • MANUAL_X_REF: C00002895 — KNApSAcK
  • MANUAL_X_REF: C05901 — KEGG COMPOUND
  • MANUAL_X_REF: DB08399 — DrugBank
  • MANUAL_X_REF: HMDB0004215 — HMDB
  • MANUAL_X_REF: LMPK13090006 — LIPID MAPS
  • MANUAL_X_REF: Piceatannol — Wikipedia
  • MANUAL_X_REF: PIT — PDBeChem

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2024-10-11. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match667639

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 50% (1 of 2) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302+H312+H332 (50%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]; H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]; H312 (50%): Harmful in contact with skin [Warning Acute toxicity, dermal]; H332 (50%): Harmful if inhaled [Warning Acute toxicity, inhalation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 1 of 2 reports by companies.; There is 1 notification provided by 1 of 2 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for PICEATANNOL

INCI name

PICEATANNOL

Description

1,2-Benzenediol, 4-[(1E)-2-(3,5-Dihydroxyphenyl)Ethenyl]-; trans-3,3',4,5'-Tetrahydroxystilbene

Record provenance

Inventory reference
83801
Imported identity
PICEATANNOL
Source update
15/10/2010
European Commission CosIng source notes
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Key data

CAS
10083-24-6
EC
—
Restriction
—
Function
ANTIOXIDANT
Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#20956 · PICEATANNOL

Ingredients with overlapping formulation functions

PHYTOSTERYL LINOLEATE/LINOLENATEANTIOXIDANT
PHYTYL RETINYL SUCCINATEANTIOXIDANT; ANTI-SEBUM
PICEA ABIES LEAF CELL EXTRACTANTIOXIDANT, SKIN PROTECTING
PICEA MARIANA BARK EXTRACTANTIOXIDANT, SKIN CONDITIONING
PICHIA KUDRIAVZEVII/SACCHAROMYCES/GRAPE PEEL/SEED/STEM FERMENT EXTRACT FILTRATEANTIOXIDANT, SKIN CONDITIONING
PICHIA R-GANODERMA MICROSPORUM POLYPEPTIDE-1 FERMENT FILTRATE EXTRACTANTIOXIDANT; SKIN PROTECTING; SKIN CONDITIONING - MISCELLANEOUS
PICHIA SR-COW POLYPEPTIDE-2 FERMENT LYSATE FILTRATEANTIOXIDANT; SKIN CONDITIONING - MISCELLANEOUS
PICHIA/R-LEUCOSPORIDIUM POLYPEPTIDE-1 CONDITIONED MEDIAANTI-SEBUM, ANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How PICEATANNOL appears in the CosIng inventory

The CosIng inventory lists PICEATANNOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PICEATANNOL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PICEATANNOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, PICEATANNOL carries the following function designation(s):

CAS 10083-24-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for PICEATANNOL

This page reproduces the CosIng inventory entry for PICEATANNOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research PICEATANNOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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