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InventoryRef 8379615/10/2010

LUTEOLIN

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-benzopyrone

LUTEOLIN is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 491-70-3
CAS 491-70-3PubChem CID 5280445

Luteolin

Luteolin is a tetrahydroxyflavone in which the four hydroxy groups are located at positions 3', 4', 5 and 7. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an anti-inflammatory agent and an immune system modulator as well as being active against several cancers. It has a role as an antineoplastic agent, an angiogenesis inhibitor, a radical scavenger, an immunomodulator, a vascular endothelial growth factor receptor antagonist, an anti-inflammatory agent, an apoptosis inducer, an EC 2.3.1.85 (fatty acid synthase) inhibitor, a nephroprotective agent, a plant metabolite and a c-Jun N-terminal kinase inhibitor. It is a 3'-hydroxyflavonoid and a tetrahydroxyflavone. It is a conjugate acid of a luteolin-7-olate. — ChEBI

IUPAC name
2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
Molecular formula
C15H10O6
Molecular weight
286.24 g/mol
Exact mass
286.04773803 Da
XLogP3
1.4
Topological polar surface area
107.0 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

3',4',5,7-TetrahydroxyflavoneDigitoflavoneLuteolol2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-oneFlacitranLuteolineSalifazideYama kariyasu
16 more reported names
Weld Lake5,7,3',4'-TetrahydroxyflavoneCyanidenon-14702-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-benzopyrone4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-KUX1ZNC9J2CHEBI:158643',4',5,7-Tetrahydroxy-FlavoneRefChem:6458207-741-0Cyanidenon 1470BismiteLuteolin (Standard)2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-oneCHEMBL1512-(3,4-dihydroxyphenyl)-5,7-dihydroxy-chromen-4-one
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for LUTEOLIN

INCI name

LUTEOLIN

Description

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-benzopyrone

Record provenance

Inventory reference
83796
Imported identity
LUTEOLIN
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
—
Function
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How LUTEOLIN appears in the CosIng inventory

The CosIng inventory lists LUTEOLIN as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

LUTEOLIN is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

LUTEOLIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, LUTEOLIN carries the following function designation(s):

CAS 491-70-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for LUTEOLIN

This page reproduces the CosIng inventory entry for LUTEOLIN from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research LUTEOLIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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