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InventoryRef 8263115/10/2010

BRYONOLIC ACID

D:C-Friedoolean-8-en-29-oic acid, 3-hydroxy-, (3beta,20beta)-

BRYONOLIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 24480-45-3
CAS 24480-45-3PubChem CID 159970

Bryonolic Acid

20-epi-bryonolic acid is a pentacyclic triterpenoid of D:C-friedooleanane-type triterpenoids isolated from the stems of Lagenaria siceraria and roots of Coriaria intermedia and has been found to exhibit antineoplastic activity. It has a role as a metabolite and an antineoplastic agent. It is a pentacyclic triterpenoid and a hydroxy monocarboxylic acid. ChEBI

IUPAC name
(2S,4aS,6aS,8aR,10S,12aS,14aS,14bR)-10-hydroxy-2,4a,6a,9,9,12a,14a-heptamethyl-1,3,4,5,6,7,8,8a,10,11,12,13,14,14b-tetradecahydropicene-2-carboxylic acid
Molecular formula
C30H48O3
Molecular weight
456.7 g/mol
Exact mass
456.36034539 Da
XLogP3
7.2
Topological polar surface area
57.5 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
8

Also known as

J7YR6A878IBIO-ACTIVE BAD:C-Friedoolean-8-en-29-oic acid, 3-hydroxy-, (3beta,20beta)-3beta-Hydroxy-D-C-friedoolean-8-en-29-oic acidRefChem:917661(20R)-3beta-hydroxy-D:C-friedoolean-8-en-29-oic acid(2R,4aS,6aS,8aR,10S,12aS,14aS,14bR)-10-hydroxy-2,4a,6a,9,9,12a,14a-heptamethyl-1,3,4,5,6,7,8,8a,10,11,12,13,14,14b-tetradecahydropicene-2-carboxylic acid20-epi-Bryonolic acid
9 more reported names
5957-43-7UNII-J7YR6A878ICHEBI:65846HY-N2965DA-51440CS-0023599D:C-Friedoolean-8-en-29-oic acid, 3beta-hydroxy-D:C-FRIEDOOLEAN-8-EN-29-OIC ACID, 3-HYDROXY-, (3.BETA.,20.BETA.)-26-NOROLEAN-8-EN-29-OIC ACID, 3-HYDROXY-13-METHYL-, (3.BETA.,13.ALPHA.,14.BETA.,20.BETA.)-
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for BRYONOLIC ACID

INCI name

BRYONOLIC ACID

Description

D:C-Friedoolean-8-en-29-oic acid, 3-hydroxy-, (3beta,20beta)-

Record provenance

Inventory reference
82631
Imported identity
BRYONOLIC ACID
Source update
15/10/2010
European Commission CosIng source notes

Key data

EC
Restriction
Function
SKIN CONDITIONING - EMOLLIENT
Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How BRYONOLIC ACID appears in the CosIng inventory

The CosIng inventory lists BRYONOLIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

BRYONOLIC ACID is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

BRYONOLIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, BRYONOLIC ACID carries the following function designation(s):

CAS 24480-45-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for BRYONOLIC ACID

This page reproduces the CosIng inventory entry for BRYONOLIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research BRYONOLIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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