Is LACTITOL safe to use in EU cosmetics?

LACTITOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 585-86-4?

CAS 585-86-4 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains LACTITOL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 7814915/10/2010

LACTITOL

4-O-.beta.-D-Galactopyranosyl-D-glucitol

LACTITOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 585-86-4

CAS 585-86-4PubChem CID 157355

Lactitol

Lactitol is a glycosyl alditol consisting of beta-D-galactopyranose and D-glucitol joined by a 14 glycosidic bond. It is used as a laxative, as an excipient, and as replacement bulk sweetener in some low-calorie foods. It has a role as a laxative, an excipient and a cathartic. — ChEBI

IUPAC name: (2S,3R,4R,5R)-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexane-1,2,3,5,6-pentol

Molecular formula: C12H24O11
Molecular weight: 344.31 g/mol
Exact mass: 344.13186158 Da
XLogP3: -5.2
Topological polar surface area: 201.0 Å²
Hydrogen-bond donors: 9
Hydrogen-bond acceptors: 11
Covalent units: 1
Defined stereocentres: 9

Also known as

4-O-beta-D-Galactopyranosyl-D-glucitolImportalD-lactitollactositolLactositMiruhenlactitolumlactobiosit

16 more reported names

Lactitol acm 50LACTITOL ANHYDROUSLacty (saccharide)MilchenLactitFinlac dcpizensyL2B0WJF7ZYINS NO.966CHEBI:75323INS-966NSC-231323E-966BLI-400NSC-759131Neda Lactiv Importal

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:75323
ChEMBL:CHEMBL1661
EPA DTXSID:DTXSID9044247
PubMed:29132732
PubMed:27153247
PubMed:23120982
PubMed:23028535
PubMed:22786523
PubMed:22700518
PubMed:22666568
PubMed:22653661
PubMed:22626795
PubMed:22573997
PubMed:22567035
PubMed:22523293

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for LACTITOL

INCI name

LACTITOL

INN name

lactitol

Description

4-O-.beta.-D-Galactopyranosyl-D-glucitol

Record provenance

Inventory reference: 78149
Imported identity: LACTITOL
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for LACTITOL

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Key data

CAS

585-86-4

209-566-5

Restriction

—

Function

HUMECTANT: Retaining and/or preserving the moisture in a product during use.
SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#14288 · LACTITOL

Ingredients with overlapping formulation functions

LACHANCEA/HYDROLYZED GERMINATED RICE GRAIN FERMENT LYSATE FILTRATEHUMECTANT

LACHANCEA/HYDROLYZED RICE FERMENT FILTRATEHUMECTANT, SKIN CONDITIONING

LACTAMIDE MEAANTISTATIC, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING

LACTIC ACIDBUFFERING, HUMECTANT, SKIN CONDITIONING

LACTOBACCILLUS/HIBISCUS SABDARIFFA CALLUS CULTURE FERMENT FILTRATEANTIMICROBIAL, ANTIOXIDANT, HUMECTANT, SKIN CONDITIONING

LACTOBACILLUS EXTRACT FILTRATEHUMECTANT, SKIN CONDITIONING

LACTOBACILLUS/ACTAEA HERACLEIFOLIA ROOT/CITRUS UNSHIU PEEL/GARDENIA FLORIDA FLO…ANTIOXIDANT, HUMECTANT, ORAL CARE, SKIN CONDITIONING

LACTOBACILLUS/AGARICUS BLAZEI EXTRACT FERMENT FILTRATEHUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How LACTITOL appears in the CosIng inventory

The CosIng inventory lists LACTITOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

LACTITOL is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

LACTITOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, LACTITOL carries the following function designation(s):

CAS 585-86-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for LACTITOL

This page reproduces the CosIng inventory entry for LACTITOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research LACTITOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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