Is OLEAMIDE MIPA safe to use in EU cosmetics?

OLEAMIDE MIPA is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What function does OLEAMIDE MIPA serve in cosmetics?

According to the EU CosIng inventory, OLEAMIDE MIPA carries the following function designation(s): ANTISTATIC, SURFACTANT - FOAM BOOSTING, VISCOSITY CONTROLLING.

What other records share CAS 111-05-7?

CAS 111-05-7 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains OLEAMIDE MIPA?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 7789115/10/2010

OLEAMIDE MIPA

N-(2-Hydroxypropyl)-(Z)-9-octadecenamide

OLEAMIDE MIPA is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Markets and their official sources Search every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 111-05-7

CAS 111-05-7PubChem CID 6436066

Oleic monoisopropanolamide

The CIR Expert Panel concluded that the 14 alkyl amide MIPA ingredients listed below are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating...Oleamide MIPA... — Cosmetic Ingredient Review (CIR)

IUPAC name: (Z)-N-(2-hydroxypropyl)octadec-9-enamide

Molecular formula: C21H41NO2
Molecular weight: 339.6 g/mol
Exact mass: 339.313729551 Da
XLogP3: 6.8
Topological polar surface area: 49.3 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

N-(2-Hydroxypropyl)oleamideOleamide MIPAOleic acid isopropanolamide9-Octadecenamide, N-(2-hydroxypropyl)-, (Z)-9-Octadecenamide, N-(2-hydroxypropyl)-, (9Z)-MACKAMIDE OP63Y91GM18SOLEOYL ISOPROPANOLAMIDE

16 more reported names

OLEYLMONOISOPROPANOLAMIDEOLEAMIDE, N-(2-HYDROXYPROPYL)-RefChem:856525OLEAMIDE MIPA [INCI](9Z)-N-(2-Hydroxypropyl)-9-octadecenamide203-828-2Oleic acid monoisopropanolamideUNII-63Y91GM18SEINECS 203-828-2N-(2-Hydroxypropyl)-9-octadecenamide(9Z)-N-(2-hydroxypropyl)octadec-9-enamideEC 203-828-2UDZAXLGLNUMCRX-KHPPLWFESA-NOLEICACIDMONOISOPROPANOLAMIDEMonoisopropanolamine oleic acid amide9-Octadecenamide, N-(2-hydroxypropyl)-

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID90883304

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match6436066

Attributed physical-property, hazard, environmental and use annotations.

Physical Description: Liquid Source: EPA Chemical Data Reporting (CDR)

Note: This chemical does not meet GHS hazard criteria for 64.8% (162 of 250) of all reports. Source: European Chemicals Agency (ECHA)
Signal: Danger Source: European Chemicals Agency (ECHA)
GHS Hazard Statements: H315 (23.6%): Causes skin irritation [Warning Skin corrosion/irritation]; H318 (11.2%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H319 (23.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
Precautionary Statement Codes: P264, P264+P265, P280, P302+P352, P305+P351+P338, P305+P354+P338, P317, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
ECHA C&L Notifications Summary: Aggregated GHS information provided per 250 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 162 of 250 reports by companies.; There are 8 notifications provided by 88 of 250 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded that the 14 alkyl amide MIPA ingredients listed below are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating...Oleamide MIPA... Source: Cosmetic Ingredient Review (CIR)
Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)

Consumer Uses: Surfactant (surface active agent); Cleaning agent Source: EPA Chemical Data Reporting (CDR)

Industry Uses: Surfactant (surface active agent) Source: EPA Chemical Data Reporting (CDR)

Cosmetic Ingredient Review Link: CIR ingredient: Oleamide MIPA Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for OLEAMIDE MIPA

INCI name

OLEAMIDE MIPA

Description

N-(2-Hydroxypropyl)-(Z)-9-octadecenamide

Record provenance

Inventory reference: 77891
Imported identity: OLEAMIDE MIPA
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for OLEAMIDE MIPA

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Key data

CAS

111-05-7

203-828-2

Restriction

—

Function

ANTISTATIC: Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
SURFACTANT - FOAM BOOSTING: Increasing foaming capacity and/or stabilizing foams in general.
VISCOSITY CONTROLLING: Increasing or decreasing the viscosity (thickness) of cosmetics.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#17940 · OLEAMIDE MIPA

Ingredients with overlapping formulation functions

OATAMIDE MEASURFACTANT - FOAM BOOSTING, VISCOSITY CONTROLLING

OATAMIDOPROPYL BETAINECLEANSING, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOSTING, VISCOSITY CONTROLLING

OLEAMIDE DEAANTISTATIC, SURFACTANT - FOAM BOOSTING, VISCOSITY CONTROLLING

OLEAMIDE MEAANTISTATIC, SURFACTANT - FOAM BOOSTING, VISCOSITY CONTROLLING

OLEAMIDOPROPYL BETAINEANTISTATIC, CLEANSING, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - F…

OLEAMIDOPROPYL HYDROXYSULTAINEANTISTATIC, CLEANSING, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - F…

OLEAMIDOPROPYLAMINE OXIDEANTISTATIC, CLEANSING, HAIR CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOSTING, SURFA…

OLEAMINE OXIDEANTISTATIC, CLEANSING, HAIR CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOSTING, SURFA…

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How OLEAMIDE MIPA appears in the CosIng inventory

The CosIng inventory lists OLEAMIDE MIPA as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

OLEAMIDE MIPA is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

OLEAMIDE MIPA is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, OLEAMIDE MIPA carries the following function designation(s):

CAS 111-05-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for OLEAMIDE MIPA

This page reproduces the CosIng inventory entry for OLEAMIDE MIPA from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research OLEAMIDE MIPA and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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