Oleic monoisopropanolamide
The CIR Expert Panel concluded that the 14 alkyl amide MIPA ingredients listed below are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating...Oleamide MIPA... — Cosmetic Ingredient Review (CIR)
- IUPAC name
- (Z)-N-(2-hydroxypropyl)octadec-9-enamide
- Molecular formula
- C21H41NO2
- Molecular weight
- 339.6 g/mol
- Exact mass
- 339.313729551 Da
- XLogP3
- 6.8
- Topological polar surface area
- 49.3 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 2
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- EPA DTXSID:DTXSID90883304
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Physical Description: Liquid Source: EPA Chemical Data Reporting (CDR)
- Note: This chemical does not meet GHS hazard criteria for 64.8% (162 of 250) of all reports. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H315 (23.6%): Causes skin irritation [Warning Skin corrosion/irritation]; H318 (11.2%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H319 (23.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P264+P265, P280, P302+P352, P305+P351+P338, P305+P354+P338, P317, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 250 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 162 of 250 reports by companies.; There are 8 notifications provided by 88 of 250 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded that the 14 alkyl amide MIPA ingredients listed below are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating...Oleamide MIPA... Source: Cosmetic Ingredient Review (CIR)
- Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)
- Consumer Uses: Surfactant (surface active agent); Cleaning agent Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Surfactant (surface active agent) Source: EPA Chemical Data Reporting (CDR)
- Cosmetic Ingredient Review Link: CIR ingredient: Oleamide MIPA Source: Cosmetic Ingredient Review (CIR)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.