Is ISOPULEGOL safe to use in EU cosmetics?

ISOPULEGOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

How do I check if my formula contains ISOPULEGOL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 7774615/10/2010

ISOPULEGOL

Cyclohexanol, 5-methyl-2-(1-methylethenyl)-, [1R-(1alfa, 2beta, 5alfa)]-

ISOPULEGOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

INCI Checker Compare all markets Search similar

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Markets and their official sources Search every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 7786-67-6

CAS 7786-67-6PubChem CID 24585

Cyclohexanol, 5-methyl-2-(1-methylethenyl)-

isopulegols has been reported in Achillea abrotanoides, Mentha suaveolens, and other organisms with data available. — LOTUS - the natural products occurrence database

IUPAC name: 5-methyl-2-prop-1-en-2-ylcyclohexan-1-ol

Molecular formula: C10H18O
Molecular weight: 154.25 g/mol
Exact mass: 154.135765193 Da
XLogP3: 3.0
Topological polar surface area: 20.2 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 1
Covalent units: 1
Defined stereocentres: 0

Also known as

8(9)-p-Menthen-3-ol5-methyl-2-(1-methylethenyl)cyclohexanol1-Methyl-4-isopropenylcyclohexan-3-ol5-Methyl-2-(1-methylvinyl)cyclohexan-1-olEINECS 232-102-8NSC 231369EC 232-102-8RefChem:580679

16 more reported names

232-102-85-methyl-2-(prop-1-en-2-yl)cyclohexan-1-oldl-isopulegol5-Methyl-2-(prop-1-en-2-yl)cyclohexanol2-Isopropenyl-5-methylcyclohexanol2-isopropenyl-5-methyl-cyclohexanolISOPULEGOL (MIXTURE OF ISOMERS)FEMA 29625-methyl-2-(1-methylethenyl)-cyclohexanolNeo-isopulegolCyclohexanol, 5-methyl-2-(1-methylethenyl)-, (1R,2S,5R)-rel-LsopulegolIsopregolIsopulegol, TechCyclohexanol, 5-methyl-2-(1-methylethenyl)-, [1R-(1.alpha.,2.beta.,5.alpha.)]-5-Methyl-2-(1-methylethenyl)cyclohexanol; 2-Isopropenyl-5-methylcyclohexanol;5-Methyl-2-(1-methylvinyl)cyclohexanol; p-Menth-8-en-3-ol

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL3560085
EPA DTXSID:DTXSID3044461
PubMed:23449869
PubMed:22945026
PubMed:22689408
PubMed:22382815
PubMed:21852995
PubMed:21420431
PubMed:21259348
PubMed:20734926
PubMed:20205230
PubMed:19722579
PubMed:19681592
PubMed:19559770

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 89-79-2

CAS 89-79-2PubChem CID 170833

(-)-Isopulegol

Isopulegol is a p-menthane monoterpenoid. It has a role as a metabolite. — ChEBI

IUPAC name: (1R,2S,5R)-5-methyl-2-prop-1-en-2-ylcyclohexan-1-ol

Molecular formula: C10H18O
Molecular weight: 154.25 g/mol
Exact mass: 154.135765193 Da
XLogP3: 3.0
Topological polar surface area: 20.2 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 1
Covalent units: 1
Defined stereocentres: 3

Also known as

Isopulegoll-Isopulegolcoolact P(1R,2S,5R)-5-METHYL-2-(PROP-1-EN-2-YL)CYCLOHEXAN-1-OLFEMA No. 29623TH92O3BXNNSC-231369RefChem:792269

16 more reported names

201-940-6p-Menth-8-en-3-olCyclohexanol, 5-methyl-2-(1-methylethenyl)-, (1R,2S,5R)-(-)-L-Isopulegol(1R,2S,5R)-2-Isopropenyl-5-methylcyclohexanolNVG8YK55NLp-8(9)-Menthen-3-olIsopulegol, (+/-)-(1R,2S,5R)-5-methyl-2-(prop-1-en-2-yl)cyclohexanolGTPL2462NSC1263p-Menth-8-en-3-ol, (1R,3R,4S)-(-)-NSC-1263EINECS 256-557-7AS-10358iso-Pulegol

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:70479
ChEMBL:CHEMBL237994
EPA DTXSID:DTXSID5047116
EPA DTXSID:DTXSID90110001
PubMed:30053451
PubMed:27607409
PubMed:19559770
PubMed:14757700

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ISOPULEGOL

INCI name

ISOPULEGOL

Description

Cyclohexanol, 5-methyl-2-(1-methylethenyl)-, [1R-(1alfa, 2beta, 5alfa)]-

Record provenance

Inventory reference: 77746
Imported identity: ISOPULEGOL
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for ISOPULEGOL

Browse

Browse EU annexes

Explore Annex II–VI to see which substances are prohibited, restricted or permitted under specific conditions.

Search annex entries

Search the annex database for entries matching ISOPULEGOL or related substances.

Key data

CAS

7786-67-6 / 89-79-2

232-102-8 / 201-940-6

Restriction

—

Function

FRAGRANCE: Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#13897 · ISOPULEGOL

Ingredients with overlapping formulation functions

ISOPROPYL CYCLOHEXYLPROPIONATEFRAGRANCE, PERFUMING

ISOPROPYL MYRISTATEBINDING, FRAGRANCE, PERFUMING, SKIN CONDITIONING - EMOLLIENT

ISOPROPYL PALMITATEBINDING, FRAGRANCE, PERFUMING, SKIN CONDITIONING - EMOLLIENT

ISOPROPYLPHENYLBUTANALFRAGRANCE, PERFUMING

JASMINUM GRANDIFLORUM FLOWER EXTRACTFRAGRANCE, PERFUMING

JASMINUM GRANDIFLORUM FLOWER OILFRAGRANCE; PERFUMING; SKIN CONDITIONING - MISCELLANEOUS

JASMINUM GRANDIFLORUM FLOWER WAXFRAGRANCE

JASMINUM OFFICINALE EXTRACTFRAGRANCE, MOISTURISING, SKIN CONDITIONING, SOOTHING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ISOPULEGOL appears in the CosIng inventory

The CosIng inventory lists ISOPULEGOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ISOPULEGOL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ISOPULEGOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ISOPULEGOL carries the following function designation(s):

FRAGRANCE

CAS 7786-67-6 / 89-79-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Open INCI Checker

Source note for ISOPULEGOL

This page reproduces the CosIng inventory entry for ISOPULEGOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ISOPULEGOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sources View updates

Tools & next steps

Check your formula

Scan a full INCI list to detect ISOPULEGOL and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to ISOPULEGOL, its identifiers or nearby name variants.