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InventoryRef 3469921/11/2016

ISOPROPYL MYRISTATE

Tetradecanoic acid, isopropyl ester

ISOPROPYL MYRISTATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 110-27-0
CAS 110-27-0PubChem CID 8042

Isopropyl Myristate

Isopropyl tetradecanoate is a fatty acid ester. ChEBI

IUPAC name
propan-2-yl tetradecanoate
Molecular formula
C17H34O2
Molecular weight
270.5 g/mol
Exact mass
270.255880323 Da
XLogP3
7.2
Topological polar surface area
26.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

Isopropyl tetradecanoateIsomystEstergelBisomelDeltyl ExtraKesscomirPromyrTetradecanoic acid, 1-methylethyl ester
16 more reported names
Crodamol IPMTegesterSinnoester MIPPlymoutm IPMStarfol IPMUnimate IPMKessco IPMEmcol-IMStepan D-50Wickenol 101Emerest 23141-Methylethyl tetradecanoateDeltylextraJA-FA IPMCrodamol I.P.M.Kessco isopropyl myristate
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8042

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 84.3% (2565 of 3041) of all reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (15.6%): Causes skin irritation [Warning Skin corrosion/irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264, P280, P302+P352, P321, P332+P317, and P362+P364 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 3041 reports by companies from 10 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 2565 of 3041 reports by companies.; There are 8 notifications provided by 476 of 3041 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)
  • Environmental Bioconcentration: An estimated BCF of 2800 was calculated in fish for isopropyl myristate(SRC), using an estimated log Kow of 7.17(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is very high(SRC), provided the compound is not metabolized by the organism(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 1.2X10+4(SRC), determined from a structure estimation method(2), indicates that isopropyl myristate is expected to be immobile in soil(SRC). Volatilization of isopropyl myristate from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 2.34X10-2 atm-cu m/mole(SRC), using a fragment constant estimation method(3). However, adsorption to soil is expected to attenuate volatilization(SRC). Isopropyl myristate is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 9.35X10-5 mm Hg at 25 °C(4). Isopropyl myristate, present at 100 mg/L, reached 94% of its chemical oxygen demand in 28 days using a municipal waste water inoculum in the closed bottle test(5), suggesting that biodegradation may be an important environmental fate process(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 1.2X10+4(SRC), determined from a structure estimation method(2), indicates that isopropyl myristate is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 2.34X10-2 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 4.9 hours and 6.5 days, respectively(SRC). However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column(SRC). The volatilization half-life from a model pond is about 99 days when adsorption is considered(5). According to a classification scheme(6), an estimated BCF of 2800(SRC), from an estimated log Kow of 7.17(7) and a regression-derived equation(2), suggests the potential for bioconcentration in aquatic organisms is very high, provided the compound is not metabolized by the organism(SRC). A base-catalyzed second-order hydrolysis rate constant of 2.14X10-2 L/mole-s Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), isopropyl myristate, which has a vapor pressure of 9.35X10-5 mm Hg at 25 °C(2), is expected to exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase isopropyl myristate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 20 hours(SRC), calculated from its rate constant of 1.92X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Particulate-phase isopropyl myristate may be removed from the air by wet or dry deposition(SRC). Isopropyl myristate does not contain chromophores that absorb at wavelengths >290 nm(4), and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Industry Uses: Not Known or Reasonably Ascertainable; Fragrance; Humectant; Defoamer; Surface modifier; Softener and conditioner; Intermediate; Chemical reaction regulator Source: EPA Chemical Data Reporting (CDR)
  • Cosmetic Ingredient Review Link: CIR ingredient: Isopropyl Myristate Source: Cosmetic Ingredient Review (CIR)
  • Sources/Uses: Used as emollient and emulsifier in cosmetics and topical medicines, parenteral solvent (intravenous solutions), and reagent in tests for sterility; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: For isopropyl myristate (USEPA/OPP Pesticide Code: 000207) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Isopropyl myristate is an effective agent for solubilizing lanolin; mixtures of up to about 50% lanolin in isopropyl myristate remain stable, free-flowing liquid at room temperature. Therefore, isopropyl myristate is used as a solubilizing, spreading, and penetrating agent in anhydrous skin lubricating lotions with high lanolin content. Isopropyl myristate leaves the skin soft and smooth without an oily surface film. It is used in bath oils, perfumes, creams lotions, lipsticks, hair preparations, shaving lotions, aerosol toiletries, and pharmaceutical ointments. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: In cosmetic and topical medicinal preparations Source: Hazardous Substances Data Bank (HSDB)
  • Uses: EMOLLIENT & EMULSIFIER IN COSMETIC OILS, CREAMS & LOTIONS, MAKEUP, LIPSTICK, SKIN LUBRICANTS, DEODORANTS, SUN SCREENS, HAIR PREPARATIONS, NAIL LACQUER REMOVER; PARENTERAL SOLVENT IN MEDICINE; REAGENT IN MEDICAL TEST FOR STERILITY Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for Isopropyl myristate (6 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ISOPROPYL MYRISTATE

INCI name

ISOPROPYL MYRISTATE

INN name

isopropyl myristate

Ph. Eur. name

isopropylis myristas

Description

Tetradecanoic acid, isopropyl ester

Record provenance

Inventory reference
34699
Imported identity
ISOPROPYL MYRISTATE
Source update
21/11/2016
European Commission CosIng source notes

Key data

Restriction
Function
BINDING
Providing adhesive properties during and after compression in cosmetic tablets and/or cakes.
FRAGRANCE
Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.
PERFUMING
Used for perfume and aromatic raw materials.
SKIN CONDITIONING - EMOLLIENT
Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How ISOPROPYL MYRISTATE appears in the CosIng inventory

The CosIng inventory lists ISOPROPYL MYRISTATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ISOPROPYL MYRISTATE is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ISOPROPYL MYRISTATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ISOPROPYL MYRISTATE carries the following function designation(s):

CAS 110-27-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for ISOPROPYL MYRISTATE

This page reproduces the CosIng inventory entry for ISOPROPYL MYRISTATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ISOPROPYL MYRISTATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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