Is LINOLENIC ACID safe to use in EU cosmetics?

LINOLENIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What function does LINOLENIC ACID serve in cosmetics?

According to the EU CosIng inventory, LINOLENIC ACID carries the following function designation(s): ANTISTATIC, CLEANSING, HAIR CONDITIONING, PERFUMING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING.

What other records share CAS 463-40-1 (CIS)?

CAS 463-40-1 (CIS) may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains LINOLENIC ACID?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 7732415/10/2010

LINOLENIC ACID

9,12,15-Octadecatrienoic acid (9Z, 12Z, 15Z)

LINOLENIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 463-40-1

CAS 463-40-1PubChem CID 5280934

Linolenic Acid

Alpha-linolenic acid is a linolenic acid with cis-double bonds at positions 9, 12 and 15. Shown to have an antithrombotic effect. It has a role as a micronutrient, a nutraceutical and a mouse metabolite. It is a linolenic acid and an omega-3 fatty acid. It is a conjugate acid of an alpha-linolenate and a (9Z,12Z,15Z)-octadeca-9,12,15-trienoate. — ChEBI

IUPAC name: (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid

Molecular formula: C18H30O2
Molecular weight: 278.4 g/mol
Exact mass: 278.224580195 Da
XLogP3: 5.9
Topological polar surface area: 37.3 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

alpha-Linolenic acid(Z,Z,Z)-9,12,15-Octadecatrienoic acidcis,cis,cis-9,12,15-Octadecatrienoic acidall-cis-9,12,15-Octadecatrienoic acidalpha Linolenic Acid9-cis,12-cis,15-cis-Octadecatrienoic acid9,12,15-Octadecatrienoic acid, (Z,Z,Z)-(9,12,15)-linolenic acid

16 more reported names

(9Z,12Z,15Z)-Octadecatrienoic acid9Z,12Z,15Z-Octadecatrienoic acidLinolenic acid, crude(Z,Z,Z)-Octadeca-9,12,15-trienoic acidKortacid 1499cis-delta9,12,15-Octadecatrienoic acidPrifrac 2942cis-Delta(9,12,15)-octadecatrienoic acid0RBV727H71NSC-2042cis-9,12,15-octadecatrienoic acid9,12,15-Octadecatrienoic acid, (9Z,12Z,15Z)-cis-9,cis-12,cis-15-Octadecatrienoic acidC18:3CHEBI:25048CHEBI:27432

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:27432
ChEMBL:CHEMBL8739
EPA DTXSID:DTXSID7025506
PubMed:40645425
PubMed:40088998
PubMed:30672636
PubMed:30561685
PubMed:29968805
PubMed:29423081
PubMed:28555106
PubMed:27106529
PubMed:26919940
PubMed:26386148
PubMed:25482063
PubMed:23619606

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for LINOLENIC ACID

INCI name

LINOLENIC ACID

Description

9,12,15-Octadecatrienoic acid (9Z, 12Z, 15Z)

Record provenance

Inventory reference: 77324
Imported identity: LINOLENIC ACID
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for LINOLENIC ACID

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Key data

CAS

463-40-1 (CIS)

207-334-8 (CIS)

Restriction

—

Function

ANTISTATIC: Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
CLEANSING: Helping to keep the body surface clean.
HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
PERFUMING: Used for perfume and aromatic raw materials.
SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT: Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.
SURFACTANT - CLEANSING: Wetting body surfaces, emulsifying or solubilizing oils, and suspending soil (generally, such ingredients contribute to the foaming and lathering properties of cleansing products).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#15430 · LINOLENIC ACID

Ingredients with overlapping formulation functions

LINOLEAMIDOPROPYL DIMONIUM LACTATEANTISTATIC

LINOLEAMIDOPROPYL ETHYLDIMONIUM ETHOSULFATEANTISTATIC, HAIR CONDITIONING

LINOLEAMIDOPROPYL PG-DIMONIUM CHLORIDE PHOSPHATEANTISTATIC

LINOLEIC ACIDANTISTATIC, CLEANSING, HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACT…

LOCUST BEAN HYDROXYPROPYLTRIMONIUM CHLORIDEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

LYSINEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

LYSINE PCAANTISTATIC, HUMECTANT, SKIN CONDITIONING

METHACRYLOYL ETHYL BETAINE/ACRYLATES COPOLYMERANTISTATIC, FILM FORMING, HAIR FIXING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How LINOLENIC ACID appears in the CosIng inventory

The CosIng inventory lists LINOLENIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

LINOLENIC ACID is also tagged with 7 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

LINOLENIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, LINOLENIC ACID carries the following function designation(s):

CAS 463-40-1 (CIS) may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for LINOLENIC ACID

This page reproduces the CosIng inventory entry for LINOLENIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research LINOLENIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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