Is LINOLEIC ACID safe to use in EU cosmetics?

LINOLEIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What function does LINOLEIC ACID serve in cosmetics?

According to the EU CosIng inventory, LINOLEIC ACID carries the following function designation(s): ANTISTATIC, CLEANSING, HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING.

What other records share CAS 60-33-3 (CIS)?

CAS 60-33-3 (CIS) may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains LINOLEIC ACID?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 7732315/10/2010

LINOLEIC ACID

9,12-Octadecadienoic acid (9Z, 12Z)-

LINOLEIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 60-33-3

CAS 60-33-3PubChem CID 5280450

Linoleic Acid

Linoleic acid is an octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) stereochemistry. It has a role as a plant metabolite, a Daphnia galeata metabolite and an algal metabolite. It is an octadecadienoic acid and an omega-6 fatty acid. It is a conjugate acid of a linoleate. — ChEBI

IUPAC name: (9Z,12Z)-octadeca-9,12-dienoic acid

Molecular formula: C18H32O2
Molecular weight: 280.4 g/mol
Exact mass: 280.240230259 Da
XLogP3: 6.8
Topological polar surface area: 37.3 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

Linolic acidTelfairic acidcis,cis-Linoleic acid9,12-Linoleic acidUnifac 6550Emersol 315alpha-Linoleic acidcis-9,cis-12-Octadecadienoic acid

16 more reported names

9Z,12Z-Linoleic acidcis,cis-9,12-Octadecadienoic acidEmersol 310(Z,Z)-9,12-Octadecadienoic acidExtra Linoleic 909Z,12Z-octadecadienoic acid9-cis,12-cis-Linoleic acidall-cis-9,12-Octadecadienoic acidLeinoleic acid9,12-Octadecadienoic acid (9Z,12Z)-Ronacare asc 39,12-Octadecadienoic acid (Z,Z)-9-cis,12-cis-Octadecadienoic acid(9Z,12Z)-Octadecadienoic acidcis-delta9,12-Octadecadienoic acid9KJL21T0QJ

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:137735
ChEBI:CHEBI:17351
ChEMBL:CHEMBL267476
EPA DTXSID:DTXSID2025505
PubMed:29968805
PubMed:21170321
PubMed:20671299
PubMed:20541177
PubMed:19440305
PubMed:16702987
PubMed:16153670
PubMed:14717706
PubMed:12629551
PubMed:12565875
PubMed:12496284
PubMed:11546665

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for LINOLEIC ACID

INCI name

LINOLEIC ACID

Description

9,12-Octadecadienoic acid (9Z, 12Z)-

Record provenance

Inventory reference: 77323
Imported identity: LINOLEIC ACID
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for LINOLEIC ACID

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Key data

CAS

60-33-3 (CIS)

200-470-9 (CIS)

Restriction

—

Function

ANTISTATIC: Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
CLEANSING: Helping to keep the body surface clean.
HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT: Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.
SURFACTANT - CLEANSING: Wetting body surfaces, emulsifying or solubilizing oils, and suspending soil (generally, such ingredients contribute to the foaming and lathering properties of cleansing products).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#15428 · LINOLEIC ACID

Ingredients with overlapping formulation functions

LINOLEAMIDOPROPYL DIMETHYLAMINE DIMER DILINOLEATEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

LINOLEAMIDOPROPYL DIMONIUM LACTATEANTISTATIC

LINOLEAMIDOPROPYL ETHYLDIMONIUM ETHOSULFATEANTISTATIC, HAIR CONDITIONING

LINOLEAMIDOPROPYL PG-DIMONIUM CHLORIDE PHOSPHATEANTISTATIC

LINOLENIC ACIDANTISTATIC, CLEANSING, HAIR CONDITIONING, PERFUMING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIE…

LOCUST BEAN HYDROXYPROPYLTRIMONIUM CHLORIDEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

LYSINEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

LYSINE PCAANTISTATIC, HUMECTANT, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How LINOLEIC ACID appears in the CosIng inventory

The CosIng inventory lists LINOLEIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

LINOLEIC ACID is also tagged with 6 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

LINOLEIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, LINOLEIC ACID carries the following function designation(s):

CAS 60-33-3 (CIS) may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for LINOLEIC ACID

This page reproduces the CosIng inventory entry for LINOLEIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research LINOLEIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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