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InventoryRef 7587615/10/2010

DIMETHYL MALEATE

Dimethyl maleate

DIMETHYL MALEATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 23055-10-9
CAS 23055-10-9PubChem CID 637568

Dimethyl Fumarate

Dimethyl fumarate is an enoate ester resulting from the formal condensation of both carboxy groups of fumaric acid with methanol. Used for treatment of adults with relapsing forms of multiple sclerosis. It has a role as an antipsoriatic and an immunomodulator. It is a methyl ester, a diester and an enoate ester. It is functionally related to a methanol and a fumaric acid. — ChEBI

IUPAC name
dimethyl (E)-but-2-enedioate
Molecular formula
C6H8O4
Molecular weight
144.12 g/mol
Exact mass
144.04225873 Da
XLogP3
0.7
Topological polar surface area
52.6 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

624-49-7TecfideraFumaric acid dimethyl esterDimethylfumarateFumadermFumaric acid, dimethyl esterBG-12Boletic acid dimethyl ester
16 more reported names
BG 12 compoundPanaclarDimethyl trans-ethylenedicarboxylateBG-00012dimethyl (2E)-but-2-enedioatetrans-Butenedioic acid dimethyl esterAllomaleic acid dimethyl esterFAG-201trans-1,2-Ethylenedicarboxylic acid dimethyl ester2-Butenedioic acid (E)-, dimethyl esterBG 00012AZL-O-211089NSC-25942NSC-167432AZL O 211089Dimethylester kyseliny fumarove
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 624-48-6
CAS 624-48-6PubChem CID 5271565

Dimethyl maleate

Dimethyl maleate is a maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with methanol. It is commonly used as a dienophile for Diels-Alder-type cycloaddition reactions in organic synthesis. It is a methyl ester, a maleate ester and a diester. It is functionally related to a methanol. — ChEBI

IUPAC name
dimethyl (Z)-but-2-enedioate
Molecular formula
C6H8O4
Molecular weight
144.12 g/mol
Exact mass
144.04225873 Da
XLogP3
0.7
Topological polar surface area
52.6 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

METHYL MALEATESipomer DMMMaleic acid, dimethyl esterDimethyl cis-butenedioate2-Butenedioic acid (Z)-, dimethyl esterDimethyl cis-ethylenedicarboxylate2-Butenedioic acid, dimethyl ester, (Z)-Dimethylester kyseliny maleinove
16 more reported names
2-Butenedioic acid (2Z)-, 1,4-dimethyl esterNSC-5161CHEBI:35460RefChem:588282210-848-5Maleic Acid Dimethyl Ester1,4-dimethyl (2Z)-but-2-enedioatedimethyl (2Z)-but-2-enedioate2-Butenedioic acid (2Z)-, dimethyl esterMaleic acid, bis-methyl esterDimethyl 2-butenedioate2-Butenedioic acid, dimethyl ester2-Butenedioic acid, dimethyl ester, (2Z)-CAS-624-48-6NSC 5161EINECS 210-848-5
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DIMETHYL MALEATE

INCI name

DIMETHYL MALEATE

Description

Dimethyl maleate

Record provenance

Inventory reference
75876
Imported identity
DIMETHYL MALEATE
Source update
15/10/2010
European Commission CosIng source notes
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Key data

CAS
624-48-6 / 23055-10-9
EC
210-848-5
Restriction
—
Function
SKIN CONDITIONING - EMOLLIENT
Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.
SOLVENT
Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#8983 · DIMETHYL MALEATE

Ingredients with overlapping formulation functions

DIMETHYL ETHERPROPELLANT, SOLVENT, VISCOSITY CONTROLLING
DIMETHYL GLUTARATEANTISTATIC, SKIN CONDITIONING - EMOLLIENT, SOLVENT
DIMETHYL ISOSORBIDESOLVENT, VISCOSITY CONTROLLING
DIMETHYL LAURAMIDE/MYRISTAMIDESOLVENT, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING, SURFACTANT - FOAM BOOSTING, VISCOSITY CO…
DIMETHYL METHYLGLUTARATESOLVENT
DIMETHYL OXALATECHELATING, PLASTICISER, SOLVENT
DIMETHYL PHTHALATEFILM FORMING, FRAGRANCE, PLASTICISER, SOLVENT
DIMETHYL SUCCINATEFRAGRANCE, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How DIMETHYL MALEATE appears in the CosIng inventory

The CosIng inventory lists DIMETHYL MALEATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DIMETHYL MALEATE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DIMETHYL MALEATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, DIMETHYL MALEATE carries the following function designation(s):

CAS 624-48-6 / 23055-10-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for DIMETHYL MALEATE

This page reproduces the CosIng inventory entry for DIMETHYL MALEATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research DIMETHYL MALEATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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