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CAS 126139-79-5 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 7577715/10/2010

DISODIUM MALYL TYROSINATE

L-Tyrosine, N-(1-oxo-2-hydroxy-3-carboxypropyl)-, disodium salt

DISODIUM MALYL TYROSINATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 126139-79-5

CAS 126139-79-5PubChem CID 71587464

Disodium Malyl Tyrosinate

The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Disodium Malyl Tyrosinate — Cosmetic Ingredient Review (CIR)

IUPAC name: disodium;(3S)-4-[[(1S)-1-carboxylato-2-(4-hydroxyphenyl)ethyl]amino]-3-hydroxy-4-oxobutanoate

Molecular formula: C13H13NNa2O7
Molecular weight: 341.22 g/mol
Exact mass: 341.04874032 Da
Topological polar surface area: 150.0 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 7
Covalent units: 3
Defined stereocentres: 2

Also known as

UNII-865390F26IL-Tyrosine, N-((2S)-3-carboxy-2-hydroxy-1-oxopropyl)-, disodium saltL-Tyrosine, N-(3-carboxy-2-hydroxy-1-oxopropyl)-, disodium salt, (S)-L-Tyrosine, N-((2S)-3-carboxy-2-hydroxy-1-oxopropyl)-, sodium salt (1:2)RefChem:135059DISODIUM MALYL TYROSINATE [INCI]Disodium (3S)-4-{[(1S)-1-carboxylato-2-(4-hydroxyphenyl)ethyl]amino}-3-hydroxy-4-oxobutanoate

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID80155087

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match71587464

Attributed physical-property, hazard, environmental and use annotations.

Cosmetic Ingredient Review Conclusion: The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Disodium Malyl Tyrosinate Source: Cosmetic Ingredient Review (CIR)
Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)

Cosmetic Ingredient Review Link: CIR ingredient: Disodium Malyl Tyrosinate Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DISODIUM MALYL TYROSINATE

INCI name

DISODIUM MALYL TYROSINATE

Description

L-Tyrosine, N-(1-oxo-2-hydroxy-3-carboxypropyl)-, disodium salt

Record provenance

Inventory reference: 75777
Imported identity: DISODIUM MALYL TYROSINATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for DISODIUM MALYL TYROSINATE

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Key data

CAS

126139-79-5

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Restriction

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Function

SKIN CONDITIONING: Maintaining the skin in good condition.
SURFACTANT - CLEANSING: Wetting body surfaces, emulsifying or solubilizing oils, and suspending soil (generally, such ingredients contribute to the foaming and lathering properties of cleansing products).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#9394 · DISODIUM MALYL TYROSINATE

Ingredients with overlapping formulation functions

DISODIUM LAURYL PHENYL ETHER DISULFONATECLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING, SURFACTANT - HYDROTROPE

DISODIUM LAURYL PHOSPHATESURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

DISODIUM LAURYL SULFOSUCCINATECLEANSING, FOAMING, SKIN CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOSTING, SURFACTA…

DISODIUM LAURYLGLUCOSIDES HYDROXYPROPYL CITRATECHELATING, CLEANSING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOS…

DISODIUM METHYLENE DINAPHTHALENESULFONATELIGHT STABILIZER, SURFACTANT - CLEANSING, SURFACTANT - HYDROTROPE

DISODIUM MYRISTAMIDO MEA-SULFOSUCCINATECLEANSING, FOAMING, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOSTING, SURFACTANT - HYDROTROPE

DISODIUM N-LAUROYL ASPARTATECLEANSING, SURFACTANT - CLEANSING

DISODIUM NONOXYNOL-10 SULFOSUCCINATECLEANSING, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOSTING, SURFACTANT - HYDROTROPE

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How DISODIUM MALYL TYROSINATE appears in the CosIng inventory

The CosIng inventory lists DISODIUM MALYL TYROSINATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DISODIUM MALYL TYROSINATE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DISODIUM MALYL TYROSINATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, DISODIUM MALYL TYROSINATE carries the following function designation(s):

CAS 126139-79-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for DISODIUM MALYL TYROSINATE

This page reproduces the CosIng inventory entry for DISODIUM MALYL TYROSINATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research DISODIUM MALYL TYROSINATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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