InventoryRef 7574215/10/2010
DIPROPYLENE GLYCOL
1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol
DIPROPYLENE GLYCOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
No rule for this ingredient has been imported for any of the 13 markets tracked here.
That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.
Chemical identity and properties
CAS 110-98-5PubChem CID 8087
1,1'-Oxydi-2-propanol
- IUPAC name
- 1-(2-hydroxypropoxy)propan-2-ol
- Molecular formula
- C6H14O3
- Molecular weight
- 134.17 g/mol
- Exact mass
- 134.094294304 Da
- XLogP3
- -0.4
- Topological polar surface area
- 49.7 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
2-Propanol, 1,1'-oxybis-Bis(2-hydroxypropyl) ether1,1'-Oxybis-2-propanol4-Oxaheptane-2,6-diol1,1'-Oxydipropan-2-ol1,1'-Dimethyldiethylene glycolNIAX catalyst D-19NSC 8688
16 more reported names
HSDB 2854EINECS 203-821-41,1'-Oxybis(2-propanol)UNII-D5SV08985ZBRN 1698372AI3-012332-PROPANOL,1,1'-OXYDI-1,1'-OXYDI-2-PROPANOL [HSDB]4Oxaheptane2,6diolNIAX catalyst D19RefChem:4093042Propanol, 1,1'oxybisBis(2hydroxypropyl) ether2,2'Dihydroxydipropyl ether1,1'Dimethyldiethylene glycol2,2'-Dihydroxydi-n-propyl ether
External database identifiers
- ChEMBL:CHEMBL3182176
- EPA DTXSID:DTXSID7026863
- PubMed:21654886
- PubMed:21159175
- PubMed:20417501
- PubMed:18855439
- PubMed:18049859
- PubMed:16010361
- PubMed:15983044
Evidence from additional scientific databases
NIH PubChem PUG-View
Exact identifier match8087
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 232.8 °C Source: Hazardous Substances Data Bank (HSDB)
- Color/Form: Colorless, slightly viscous liquid Source: Hazardous Substances Data Bank (HSDB)
- Density: 1.0252 at 20 °C/20 °C Source: Hazardous Substances Data Bank (HSDB)
- Density: Coefficient of expansion: 0.00073/K at 20 °C; bulk density:8.5 lb/gal at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 137.7 °C Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Flash Point: 280 °F (open cup) Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: less than -40 °C Source: Hazardous Substances Data Bank (HSDB)
- Odor: Nearly odorless Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Liquid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Colorless liquid; [Hawley] Viscous hygroscopic liquid; [MSDSonline] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Refractive Index: Index of refraction: 1.439 at 25 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: In water, 100 g/L /1X10+5 mg/L/, temperature not specified Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Soluble in toluene Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Miscible with ether Source: Hazardous Substances Data Bank (HSDB)
- Vapor Pressure: 0.03 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Vapor Pressure: VP: 0.03 mm Hg at 25 °C (extrapolated) Source: Hazardous Substances Data Bank (HSDB)
- Vapor Pressure: VP: 1 mm Hg at 73.8 °C Source: Hazardous Substances Data Bank (HSDB)
- Viscosity: 1.07 cP at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Note: This chemical does not meet GHS hazard criteria for 97.2% (1893 of 1947) of all reports. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 1893 of 1947 companies (only 2.8% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 1947 reports by companies from 6 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 1893 of 1947 reports by companies.; There are 5 notifications provided by 54 of 1947 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- NFPA Health Rating: 1 - Materials that, under emergency conditions, can cause significant irritation. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Fire Rating: 1 - Materials that must be preheated before ignition can occur. Materials require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Instability Rating: 0 - Materials that in themselves are normally stable, even under fire conditions. Source: Hazardous Substances Data Bank (HSDB)
- Toxicity Summary: IDENTIFICATION AND USE: 1,1'-Oxydi-2-propanol is a colorless slightly viscous liquid that is nearly odorless. Commercial dipropylene glycol is composed of 3 isomers and is typically 98% pure. The commercial product is typically composed of up to 48% of the isomer 1,1'-oxydi-2-propanol. 1,1'-Oxydi-2-propanol is registered for use as an approved pesticide in the USA but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. It is also used as a solvent and in the production of polyester and alkyd resins, reinforced plastics, and plasticizers. Uses for dipropylene glycol include in printing industry, in antifreeze, and air sanitation, since its vapor is highly germicidal. HUMAN EXPOSURE AND TOXICITY: There is no human toxicity data reported for 1,1'-oxydi-2-propanol. ANIMAL STUDIES: All toxicity data reported is for the related chemical dipropylene glycol. Although more acutely depressant to the central nervous system than ethylene, diethylene or propylene glycol, dipropylene glycol is still low in toxicity to animals, especially to the liver. It is not irritating to the skin and is not absorbed in tox Source: Hazardous Substances Data Bank (HSDB)
- Environmental Bioconcentration: BCFs of <2.2-4.6 and 0.3-1.4 were reported in carp (Cyprinus carpio) exposed over a 6 week period to 0.3 and 3 mg/L of 2,2'-dihydroxydi-n-propyl ester, respectively(1). According to a classification scheme(2), these BCFs suggest bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 1(SRC), determined from a structure estimation method(2), indicates that 2,2'-dihydroxydi-n-propyl ester is expected to have very high mobility in soil(SRC). Volatilization of 2,2'-dihydroxydi-n-propyl ester from moist soil surfaces is not expected(SRC) given an estimated Henry's Law constant of 3.6X10-9 atm-cu m/mole(SRC), using a fragment constant estimation method(2). 2,2'-Dihydroxydi-n-propyl ester is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 6.3X10-3 mm Hg at 25 °C(SRC), determined from a fragment constant method(2). A 1% of theoretical BOD using activated sludge in the Japanese MITI test(3) suggests that biodegradation is not an important environmental fate process in soil(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 1(SRC), determined from a structure estimation method(2), indicates that 2,2'-dihydroxydi-n-propyl ester is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 3.6X10-9 atm-cu m/mole(SRC), developed using a fragment constant estimation method(2). 2,2'-Dihydroxydi-n-propyl ester is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(3). According to a classification scheme(4), BCFs of <2.2-4.6 and 0.3-1.4 reported in carp (Cyprinus carpio) exposed over a 6 week period to 0.3 and 3 mg/L of 2,2'-dihydroxydi-n-propyl ester(5), respectively, suggest bioconcentration in aquatic organisms is low(SRC). A 1% of theoretical BOD using activated sludge in the Japanese MITI test(5) suggests that biodegradation is not an important environmental fate process in water(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 2,2'-dihydroxydi-n-propyl ester, which has an estimated vapor pressure of 6.3X10-3 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 2,2'-dihydroxydi-n-propyl ester is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 12 hours(SRC), calculated from its rate constant of 3.1X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(2). 2,2'-Dihydroxydi-n-propyl ester does not contain chromophores that absorb at wavelengths >290 nm(3) and, therefore, is not expected to be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Consumer Uses: Fragrance Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Fragrance Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Used in polyesters, alkyd resins, and reinforced plastics; Used as a plasticizer, solvent, extracting agent, and antifreeze; [HSDB] Used in pesticides and as a humectant and emollient in cosmetics and fragrances; Also used in dyes, inks, paints, coatings, hydraulic brake fluids, and cutting oils; [eChemPortal: SIDSUNEP] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Metal Machining [Category: Heat or Machine]; Painting (Pigments, Binders, and Biocides) [Category: Paint]; Farming (Pesticides) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: For 1,1'- oxybis-2-propanol (USEPA/OPP Pesticide Code: 068604) ACTIVE products with label matches. /SRP: Registered for use in the USA but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
- Uses: Polyester and alkyd resins, reinforced plastics, plasticizers, solvent. Source: Hazardous Substances Data Bank (HSDB)
- Uses: In printing indust, especially as water-miscible solvent in 'steam-setting' types of printing ink /Dipropylene glycol/ Source: Hazardous Substances Data Bank (HSDB)
- Uses: In extraction of aromatic hydrocarbons, mixed with ethylene glycol in proportion of 65/35%; antifreeze agent /Dipropylene glycol/ Source: Hazardous Substances Data Bank (HSDB)
- Uses: Air sanitation, since its vapor is highly germicidal /Dipropylene glycol/ Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 25265-71-8PubChem CID 134692469
Dipropylene Glycol
Thick odorless, colorless liquid. Sinks and mixes with water. (USCG, 1999) — CAMEO Chemicals
- IUPAC name
- 2-(1-hydroxypropan-2-yloxy)propan-1-ol;1-(2-hydroxypropoxy)propan-2-ol
- Molecular formula
- C12H28O6
- Molecular weight
- 268.35 g/mol
- Exact mass
- 268.18858861 Da
- Topological polar surface area
- 99.4 Ų
- Hydrogen-bond donors
- 4
- Hydrogen-bond acceptors
- 6
- Covalent units
- 2
- Defined stereocentres
- 0
Also known as
Dipropylenglykol4-Oxa-2,6-heptandiolE107L85C40EPA Pesticide Chemical Code 068604RefChem:57330Abelia seaweed refining maskAbelia green tea energy maskAbelia cucumber soothing mask
16 more reported names
Abelia lemon brightening maskAbelia collagen amplifying maskProfessional Level Brighting PenAbelia pomegranate bounce up maskAbelia royal jelly nutrition maskAbelia aloe vera moisturizing mask246-770-3DipropyleneglycolNSC-8688OxybispropanolPropanol, oxybis-Dowanol DPGCaswell No. 399EDPG-FCDPG-RFADK DPG-RF
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for DIPROPYLENE GLYCOL
INCI name
DIPROPYLENE GLYCOL
Description
1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol
Record provenance
- Inventory reference
- 75742
- Imported identity
- DIPROPYLENE GLYCOL
- Source update
- 15/10/2010
Annex records for DIPROPYLENE GLYCOL
Key data
CAS
110-98-5 / 25265-71-8
EC
203-821-4 / 246-770-3
Restriction
—
Function
- FRAGRANCE
- Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.
- PERFUMING
- Used for perfume and aromatic raw materials.
- SOLVENT
- Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).
- VISCOSITY CONTROLLING
- Increasing or decreasing the viscosity (thickness) of cosmetics.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal
How DIPROPYLENE GLYCOL appears in the CosIng inventory
The CosIng inventory lists DIPROPYLENE GLYCOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
DIPROPYLENE GLYCOL is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
DIPROPYLENE GLYCOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.
According to the EU CosIng inventory, DIPROPYLENE GLYCOL carries the following function designation(s):
CAS 110-98-5 / 25265-71-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.
Source note for DIPROPYLENE GLYCOL
This page reproduces the CosIng inventory entry for DIPROPYLENE GLYCOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research DIPROPYLENE GLYCOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
Check your formula
Scan a full INCI list to detect DIPROPYLENE GLYCOL and any linked EU annex restrictions or allergen flags.
INCI CheckerSearch similar ingredients
Find other inventory ingredients and annex entries related to DIPROPYLENE GLYCOL, its identifiers or nearby name variants.
Search