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InventoryRef 7473715/10/2010

BUTYL ACETATE

n-Butyl acetate

BUTYL ACETATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 123-86-4
CAS 123-86-4PubChem CID 31272

Butyl Acetate

Butyl acetate is the acetate ester of butanol. It has a role as a metabolite. It is functionally related to a butan-1-ol. ChEBI

IUPAC name
butyl acetate
Molecular formula
C6H12O2
Molecular weight
116.16 g/mol
Exact mass
116.083729621 Da
XLogP3
1.8
Topological polar surface area
26.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

N-BUTYL ACETATEAcetic acid, butyl esterButyl ethanoate1-Butyl acetateAcetic Acid Butyl Estern-Butyl ethanoateButylacetatAcetate de butyle
16 more reported names
Acetic acid n-butyl esterButylacetaten1-acetoxybutaneOctan n-butyluButyle (acetate de)Butylester kyseliny octoveButile (acetati di)NSC-9298Acetic acid, n-butyl ester464P5N1905FEMA NO. 2174CHEBI:31328RefChem:122222204-658-1n-ButylacetateButyl ester of acetic acid
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match31272

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
  • First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: Water flush promptly - If this chemical contacts the skin, flush the contaminated skin with water promptly. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water promptly. If irritation persists after washing, get medical attention.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
  • Signal: Warning Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H226: Flammable liquid and vapor [Warning Flammable liquids]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P261, P271, P280, P303+P361+P353, P304+P340, P319, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Note: This chemical does not meet GHS hazard criteria for 0.3% (12 of 4374) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H226 (99.2%): Flammable liquid and vapor [Warning Flammable liquids]; H336 (99.7%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P261, P271, P280, P303+P361+P353, P304+P340, P319, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 4374 reports by companies from 88 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 12 of 4374 reports by companies.; There are 87 notifications provided by 4362 of 4374 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H225: Highly Flammable liquid and vapor [Danger Flammable liquids]; H320: Causes eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]; H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P261, P264+P265, P271, P273, P280, P303+P361+P353, P304+P340, P305+P351+P338, P319, P337+P317, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: H225: Highly Flammable liquid and vapor [Danger Flammable liquids]; H320: Causes eye irritation [Warning Serious eye damage/eye irritation]; H331: Toxic if inhaled [Danger Acute toxicity, inhalation]; H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure] Source: NITE-CMC
  • NFPA Health Rating: 2 - Materials that, under emergency conditions, can cause temporary incapacitation or residual injury. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Fire Rating: 3 - Liquids and solids that can be ignited under almost all ambient temperature conditions. Materials produce hazardous atmospheres with air under almost all ambient temperatures or, though unaffected by ambient temperatures, are readily ignited under almost all conditions. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Instability Rating: 0 - Materials that in themselves are normally stable, even under fire conditions. Source: Hazardous Substances Data Bank (HSDB)
  • Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)
  • Toxicity Summary: IDENTIFICATION AND USE: n-Butyl acetate is a colorless liquid. It is used in manufacture of lacquer, artificial leather, photographic films, plastics, and safety glass. It is also used as an organic solvent and synthetic flavoring ingredient. HUMAN STUDIES: Male and female volunteers were exposed to different concentrations of n-butyl acetate vapor for 2 to 5 minutes. With exposure at 200 ppm for 3 to 5 minutes, the majority of the subjects complained of throat irritation; at 300 ppm for 3 to 5 minutes, the majority reported eye and nose irritation and severe throat irritation. In cases of severe overexposure, weakness, drowsiness, and unconsciousness have been seen. Chronic exposure to n-butyl acetate in humans has been associated with mild skin irritation. Repeated contact of the skin with the liquid may lead to defatting and cracking. Workers exposed chronically to n-butyl acetate have reported conjunctival irritation, feeling of chest constriction, and coughing. However, permanent lesions of the eyes and respiratory tract and other systemic effects have been reported in an occupational setting only when n-butyl acetate is present in a mixture with other solvents, and these effe Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: An estimated BCF of 7 was calculated in fish for n-butyl acetate(SRC), using a log Kow of 1.78(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 19(SRC), determined from a structure estimation method(2), indicates that n-butyl acetate is expected to have very high mobility in soil(SRC). Volatilization of n-butyl acetate from moist soil surfaces is expected to be an important fate process(SRC) given a Henry's Law constant of 2.81X10-4 atm-cu m/mole(3). n-Butyl acetate is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 11.5 mm Hg at 25 °C(4). Using a standard BOD dilution technique and a sewage inoculum, theoretical BODs of 56% to 86% were observed during 5 and 20 day incubation periods(5), suggesting that n-butyl acetate may biodegrade in soil(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 19(SRC), determined from a structure estimation method(2), indicates that n-butyl acetate is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon a Henry's Law constant of 2.81X10-4 atm-cu m/mole(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 6.5 hours and 5.3 days, respectively(SRC). According to a classification scheme(5), an estimated BCF of 7(SRC), from its log Kow of 1.78(6) and a regression-derived equation(2), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Hydrolysis may be an important environmental fate for this compound based upon experimentally determined hydrolysis half-lives of 2 yrs and 78 days at pH 7 and 8, respectively(2). Using river water as seed, 5-day and 20-day theoretical BODs of 20.9% and 55.4%, respectively, were measured(7), suggesting that biodegradation may be an important environmental fate process in water(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), n-butyl acetate, which has a vapor pressure of 11.5 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase n-butyl acetate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 3.2 days(SRC), calculated from its rate constant of 4.9X10-12 cu cm/molecule-sec at 25 °C(3). n-Butyl acetate does not contain chromophores that absorb at wavelengths >290 nm(4) and, therefore, is not expected to be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Consumer Uses: Binder; Other; Solvent; Dispersing agent; Monomers; Processing aids not otherwise specified; Solubility enhancer; Corrosion inhibitor; Not Known or Reasonably Ascertainable; Filler; Sealant (barrier); Plasticizer; Surface modifier; Adhesion/cohesion promoter; Hardener Source: EPA Chemical Data Reporting (CDR)
  • Industry Uses: Surface modifier; Intermediate; Adhesion/cohesion promoter; Drier; Diluent; Not Known or Reasonably Ascertainable; Cleaning agent; Plasticizer; Fuel; Fuel agents; Processing aids not otherwise specified; Solubility enhancer; Other; Flavoring and nutrient; Polymerization promoter; Solvent; Dispersing agent Source: EPA Chemical Data Reporting (CDR)
  • Cosmetic Ingredient Review Link: CIR ingredient: Butyl Acetate Source: Cosmetic Ingredient Review (CIR)
  • Sources/Uses: Used in solvent mixtures and to produce nitrocellulose lacquers, photographic film, nail polish removers, perfumes, oils, fats, vinyl resins, and camphor; Also used in food preservatives, inks, and printing processes; Occurs naturally in bananas; [ACGIH] In semiconductor manufacturing, n-butyl acetate is used to develop the pattern in the photoresists; [CHS, p. 44] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Semiconductor Manufacturing [Category: Industry]; Painting (Solvents) [Category: Paint]; Textiles (Printing, Dyeing, or Finishing) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: Manufacture of lacquer, artificial leather, photographic films, plastics, safety glass. Organic solvent. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Butyl acetate is used primarily in coatings. It is a good solvent with low volatility. The lacquer and enamel industries employ butyl acetate as a solvent for making acylic polymers, vinyl resins, and nitrocellulose. Other industries utilizing the acetate as solvent include printing, photographic, adhesives, extraction, and pharmaceutical. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Reported uses (ppm):; Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association, 1994) [Table#506] Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Dehydrating agent used in processing of oils and pharmaceuticals; solvent for paper coatings, and other protective coatings Source: Hazardous Substances Data Bank (HSDB)
  • Uses: n-Butyl acetate is an important solvent in the production of ... airplane dopes. Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for BUTYL ACETATE

INCI name

BUTYL ACETATE

Description

n-Butyl acetate

Record provenance

Inventory reference
74737
Imported identity
BUTYL ACETATE
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
Function
FRAGRANCE
Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.
SOLVENT
Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How BUTYL ACETATE appears in the CosIng inventory

The CosIng inventory lists BUTYL ACETATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

BUTYL ACETATE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

BUTYL ACETATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, BUTYL ACETATE carries the following function designation(s):

CAS 123-86-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for BUTYL ACETATE

This page reproduces the CosIng inventory entry for BUTYL ACETATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research BUTYL ACETATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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