THIODIPROPIONIC ACID
3,3'-Thiodipropionic Acid
THIODIPROPIONIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
No rule for this ingredient has been imported for any of the 13 markets tracked here.
That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.
Chemical identity and properties
Thiodipropionic Acid
3,3'-Thiobispropanoic acid is a dicarboxylic acid. — ChEBI
- IUPAC name
- 3-(2-carboxyethylsulfanyl)propanoic acid
- Molecular formula
- C6H10O4S
- Molecular weight
- 178.21 g/mol
- Exact mass
- 178.02997997 Da
- XLogP3
- -0.1
- Topological polar surface area
- 99.9 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 5
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:165380
- ChEMBL:CHEMBL1569439
- EPA DTXSID:DTXSID8044200
- PubMed:21580490
- PubMed:21535512
- PubMed:21469165
- PubMed:20924576
- PubMed:20634504
- PubMed:20332019
- PubMed:19959574
- PubMed:19708884
- PubMed:19625429
- PubMed:19001372
- PubMed:17969136
- PubMed:17370275
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Color/Form: NACREOUS LEAFLETS FROM HOT WATER Source: Hazardous Substances Data Bank (HSDB)
- Dissociation Constants: K AT 25 °C: 7.8X10-5 Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: 134 °C Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: 134 °C Source: Human Metabolome Database (HMDB)
- Physical Description: Liquid; Dry Powder Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Solid; [Merck Index] Lustrous pearlescent solid; [CHEMINFO] White powder with a stench; [Alfa Aesar MSDS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: Solid Source: Human Metabolome Database (HMDB)
- Solubility: FREELY SOL IN HOT WATER, ALC, ACETONE; 1 G DISSOLVES IN 26.9 ML WATER @ 26 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: 37.2 mg/mL at 26 °C Source: Human Metabolome Database (HMDB)
- Vapor Pressure: 0.0000143 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Signal: Danger Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H318 (69.1%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H319 (30.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264+P265, P280, P305+P351+P338, P305+P354+P338, P317, and P337+P317 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 165 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: NITE-CMC
- GHS Hazard Statements: H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] Source: NITE-CMC
- Precautionary Statement Codes: P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concludes that Dilauryl Thiodipropionate, Thiodipropionic Acid, Dicetyl Thiodipropionate, Dimyristyl Thiodipropionate, Distearyl Thiodipropionate, and Ditridecyl Thiodipropionate are safe as cosmetic ingredients in the practices of use and concentration given in this safety assessment when formulated to be non-irritating. Source: Cosmetic Ingredient Review (CIR)
- Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)
- Consumer Uses: Stabilizing agent Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Stabilizing agent; Monomers Source: EPA Chemical Data Reporting (CDR)
- Cosmetic Ingredient Review Link: CIR ingredient: Thiodipropionic Acid Source: Cosmetic Ingredient Review (CIR)
- Sources/Uses: Used as an antioxidant for soap products, ethylene polymers, and edible fats and oils; Also used in plasticizers, lubricants, pharmaceuticals, and food packaging; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: ANTIOXIDANT FOR SOAP PRODUCTS & POLYMERS OF ETHYLENE; IN PLASTICIZERS AND LUBRICANTS Source: Hazardous Substances Data Bank (HSDB)
- Uses: PRESERVATIVE & ANTIOXIDANT FOR EDIBLE FATS & OILS; PHARMACEUTICALS; FOOD PACKAGING INGREDIENT Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for THIODIPROPIONIC ACID
INCI name
THIODIPROPIONIC ACID
Description
3,3'-Thiodipropionic Acid
Record provenance
- Inventory reference
- 60300
- Imported identity
- THIODIPROPIONIC ACID
- Source update
- 15/10/2010
Annex records for THIODIPROPIONIC ACID
Key data
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How THIODIPROPIONIC ACID appears in the CosIng inventory
The CosIng inventory lists THIODIPROPIONIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
THIODIPROPIONIC ACID is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for THIODIPROPIONIC ACID
This page reproduces the CosIng inventory entry for THIODIPROPIONIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research THIODIPROPIONIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
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