Is TETRAPEPTIDE-3 safe to use in EU cosmetics?

TETRAPEPTIDE-3 is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

How do I check if my formula contains TETRAPEPTIDE-3?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 6025115/10/2010

TETRAPEPTIDE-3

Tetrapeptide-3 is a synthetic peptide containing glysine, histidine and lysine residues

TETRAPEPTIDE-3 is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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What the official INCI name states

The official label identifies a peptide- or protein-related cosmetic material.

Identity type from wording: peptide_or_protein

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Inventory details for TETRAPEPTIDE-3

INCI name

TETRAPEPTIDE-3

Description

Tetrapeptide-3 is a synthetic peptide containing glysine, histidine and lysine residues

Record provenance

Inventory reference: 60251
Imported identity: TETRAPEPTIDE-3
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for TETRAPEPTIDE-3

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Key data

CAS

—

The CosIng inventory records no CAS number for this ingredient. That is the absence of an identifier in the source, not a finding about the substance.

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Restriction

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Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Ingredients with overlapping formulation functions

TETRAPEPTIDE-26SKIN CONDITIONING

TETRAPEPTIDE-27SKIN CONDITIONING

TETRAPEPTIDE-28SKIN CONDITIONING

TETRAPEPTIDE-29SKIN CONDITIONING

TETRAPEPTIDE-30SKIN CONDITIONING, SKIN PROTECTING

TETRAPEPTIDE-31SKIN CONDITIONING

TETRAPEPTIDE-33ANTIOXIDANT, SKIN CONDITIONING

TETRAPEPTIDE-34SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How TETRAPEPTIDE-3 appears in the CosIng inventory

The CosIng inventory lists TETRAPEPTIDE-3 as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TETRAPEPTIDE-3 is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TETRAPEPTIDE-3 is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, TETRAPEPTIDE-3 carries the following function designation(s):

SKIN CONDITIONING

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Source note for TETRAPEPTIDE-3

This page reproduces the CosIng inventory entry for TETRAPEPTIDE-3 from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research TETRAPEPTIDE-3 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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