What does the restriction note for TOSYLAMIDE mean?

The restriction field for TOSYLAMIDE reads: II/307. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

How do I check if my formula contains TOSYLAMIDE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 5978418/11/2016

TOSYLAMIDE

4-Toluenesulfonamide

TOSYLAMIDE is linked to 1 EU annex record on this page. Inventory note: II/307.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 70-55-3

CAS 70-55-3PubChem CID 6269

P-Toluenesulfonamide

Toluene-4-sulfonamide is a sulfonamide that is benzenesulfonamide bearing a methyl group at position 4. — ChEBI

IUPAC name: 4-methylbenzenesulfonamide

Molecular formula: C7H9NO2S
Molecular weight: 171.22 g/mol
Exact mass: 171.03539970 Da
XLogP3: 0.8
Topological polar surface area: 68.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

4-ToluenesulfonamideTosylamidep-TosylamideToluene-4-sulfonamideBenzenesulfonamide, 4-methyl-para-Toluenesulfonamidep-Toluenesulfonylamidep-Tolylsulfonamide

16 more reported names

p-MethylbenzenesulfonamideTolylsulfonamideToluene-4-sulphonamideToluene-p-sulphonamide4-ToluenesulfanamideTOLUENESULFONAMIDE, P-4-Toluenesulfonic acid, amideNSC-9908I8266RI90MCHEBI:344354-toluenesulfonylamidepara-toluenesulphonamideRefChem:858209PTS100PTS 100200-741-1

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:34435
ChEMBL:CHEMBL574
EPA DTXSID:DTXSID8029105
PubMed:22981335
PubMed:22699123
PubMed:22672002
PubMed:22349413
PubMed:22260345
PubMed:22260170
PubMed:22092039
PubMed:22091174
PubMed:22065172
PubMed:22058909
PubMed:21916460
PubMed:21754893

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 88-19-7

CAS 88-19-7PubChem CID 6924

2-Methylbenzenesulfonamide

IUPAC name: 2-methylbenzenesulfonamide

Molecular formula: C7H9NO2S
Molecular weight: 171.22 g/mol
Exact mass: 171.03539970 Da
XLogP3: 0.8
Topological polar surface area: 68.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

O-TOLUENESULFONAMIDE2-ToluenesulfonamideBenzenesulfonamide, 2-methyl-o-Methylbenzenesulfonamideortho-Toluenesulfonamide2-TolylsulfonamideOrtho-toluol-sulfonamidortho-Toluenesulphonamide

16 more reported names

R81Z6V889PNSC-2185o-toluolsulfonamideRefChem:910086201-808-82-methylbenzene-1-sulfonamideTOLUENESULFONAMIDEToluene-2-sulfonamideToluene-2-sulphonamideNSC 21858013-74-92-Methylbenzene-1-sulphonamideKetjenflex 9Santicizer 9Ketjenflex 9So-(Or p)-toluenesulphonamide

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL176892
EPA DTXSID:DTXSID7021362
PubMed:22199961
PubMed:22091081
PubMed:21754490
PubMed:21754489
PubMed:21579088
PubMed:21577654
PubMed:21523184
PubMed:21522316
PubMed:19371963
PubMed:18613664
PubMed:18302350
PubMed:18179813

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TOSYLAMIDE

INCI name

TOSYLAMIDE

Description

4-Toluenesulfonamide

Record provenance

Inventory reference: 59784
Imported identity: TOSYLAMIDE
Source update: 18/11/2016

European Commission CosIng source notes

Annex records for TOSYLAMIDE

Annex II Restriction reference

Entry 307

Sulphonamides (sulphanilamide and its derivatives obtained by substitution of one or more H-atoms o…

Key data

CAS

70-55-3 / 88-19-7

200-741-1 / 201-808-8

Restriction

II/307

Function

PLASTICISER: Softening and making supple synthetic polymers that otherwise could not be easily deformed, spread or worked out.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#28984 · TOSYLAMIDE

Ingredients with overlapping formulation functions

SUCROSE ACETATE ISOBUTYRATEFILM FORMING, PLASTICISER

SUCROSE BENZOATEFILM FORMING, PLASTICISER

TILIA TOMENTOSA BUD EXTRACTHAIR CONDITIONING, PLASTICISER, SKIN CONDITIONING

TISOCHRYSIS LUTEA WAXPLASTICISER; VISCOSITY CONTROLLING

TOSYLAMIDE/EPOXY RESINFILM FORMING, PLASTICISER

TOSYLAMIDE/FORMALDEHYDE RESINFILM FORMING, PLASTICISER

TRI-C14-15 ALKYL CITRATEPLASTICISER, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

TRIACETINANTIMICROBIAL, FILM FORMING, FRAGRANCE, PLASTICISER, SOLVENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How TOSYLAMIDE appears in the CosIng inventory

The CosIng inventory lists TOSYLAMIDE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TOSYLAMIDE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TOSYLAMIDE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for TOSYLAMIDE reads: "II/307". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, TOSYLAMIDE carries the following function designation(s):

PLASTICISER

CAS 70-55-3 / 88-19-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for TOSYLAMIDE

This page combines the CosIng inventory entry for TOSYLAMIDE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research TOSYLAMIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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