Skip to main content
CosIng Checker
CosIng Checker
EU cosmetic ingredients, restrictions and safety
Login
InventoryRef 3864515/10/2010

TRIACETIN

Triacetin

TRIACETIN is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

INCI CheckerCompare all markets Search similar

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Markets and their official sourcesSearch every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 102-76-1
CAS 102-76-1PubChem CID 5541

Triacetin

Triacetin is a triglyceride obtained by acetylation of the three hydroxy groups of glycerol. It has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections. It has a role as a solvent, an adjuvant, a fuel additive, a food emulsifier, a plant metabolite, a food humectant, a food additive carrier and an antifungal drug. It is functionally related to an acetic acid. — ChEBI

IUPAC name
2,3-diacetyloxypropyl acetate
Molecular formula
C9H14O6
Molecular weight
218.20 g/mol
Exact mass
218.07903816 Da
XLogP3
0.2
Topological polar surface area
78.9 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

Glyceryl triacetateGlycerol triacetateEnzactinTriacetineTriacetylglycerolGlycerin triacetateFungacetinGlyped
16 more reported names
VanayKesscoflex TRAKodaflex triacetinTriacetyl glycerineTriacetina1,2,3-Propanetriol, triacetateTriacetinum1,2,3-Propanetriol triacetate1,2,3-triacetoxypropaneUjostabilTriacetyl glycerolEstol 1581FEMA No. 20071,2,3-Propanetriyl triacetateGlyceryltriacetateIns no.1518
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:9661

triacetin

A triglyceride obtained by acetylation of the three hydroxy groups of glycerol. It has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections.

Formula
C9H14O6
Average mass
218.205 g/mol
Monoisotopic mass
218.07904 Da
Formal charge
0
  • triglyceride — is a (CHEBI:17855)
  • plant metabolite — has role (CHEBI:76924)
  • solvent — has role (CHEBI:46787)
  • fuel additive — has role (CHEBI:62803)
  • adjuvant — has role (CHEBI:60809)
  • antifungal drug — has role (CHEBI:86327)
  • food additive carrier — has role (CHEBI:78059)
  • food emulsifier — has role (CHEBI:63047)
  • food humectant — has role (CHEBI:77969)
  • acetic acid — has functional parent (CHEBI:15366)
  • plant metabolite — has role (CHEBI:76924)
  • solvent — has role (CHEBI:46787)
  • fuel additive — has role (CHEBI:62803)
  • adjuvant — has role (CHEBI:60809)
  • antifungal drug — has role (CHEBI:86327)
  • food additive carrier — has role (CHEBI:78059)
  • food emulsifier — has role (CHEBI:63047)
  • food humectant — has role (CHEBI:77969)
  • triglyceride — is a (CHEBI:17855)
Additional curated names
propane-1,2,3-triyl triacetate1,2,3-Propanetriol triacetate1,2,3-Propanetriyl triacetate1,2,3-triacetoxypropane1,2,3-triacetylglycerol2-(Acetyloxy)-1-[(acetyloxy)methyl]ethyl acetateE 1518E-1518E1518Estol 1581FEMA NO. 2007glycerin triacetateGlycerol triacetateGlyceryl triacetateGlyceryltriacetateIns-1518Ins no.1518NSC-4796Triacetyl glycerinTriacetyl glycerineTriacetylglycerolUjostabil
Cross-references from this source

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2017-02-22. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match5541

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 99.8% (1973 of 1977) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 1973 of 1977 companies (only 0.2% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 1977 reports by companies from 5 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 1973 of 1977 reports by companies.; There are 3 notifications provided by 4 of 1977 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 1 of 1 companies. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • NFPA Health Rating: 0 - Materials that, under emergency conditions, would offer no hazard beyond that of ordinary combustible materials. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Fire Rating: 1 - Materials that must be preheated before ignition can occur. Materials require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Instability Rating: 0 - Materials that in themselves are normally stable, even under fire conditions. Source: Hazardous Substances Data Bank (HSDB)
  • Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)
  • Toxicity Summary: IDENTIFICATION AND USE: Triacetin, also known as glyceryl triacetate (GTA), is a colorless liquid. It is reported to function as a cosmetic biocide, plasticizer, and solvent in cosmetic formulations. Triacetin is also used as a cellulose plasticizer in the manufacture of cigarette filters, as a carrier in fungicidal compositions, and to remove carbon dioxide from natural gas. Triacetin was affirmed as a GRAS (generally recognized as safe) human food ingredient by FDA. Triacetin has been used experimentally for the treatment of Canavan disease, a fatal dysmyelinating genetic disorder associated with aspartoacylase deficiency, resulting in decreased brain acetate levels and reduced myelin lipid synthesis in the developing brain. HUMAN EXPOSURE AND TOXICITY: In humans, commercial Triacetin has caused ocular irritation but no injury. Triacetin was not an irritant or a sensitizer in a clinical maximization study, and only very mild reactions were seen in a Duhring-chamber test using a 50% dilution. In sensitive individuals, it may cause slight irritation. ANIMAL STUDIES: Triacetin is moderately toxic by intraperitoneal, subcutaneous, and intravenous routes. The symptoms of toxicity with Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: An estimated BCF of 3 was calculated in fish for triacetin(SRC), using a log Kow of 0.25(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 40(SRC), determined from a structure estimation method(2), indicates that triacetin is expected to have very high mobility in soil(SRC). Volatilization of triacetin from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 1.2X10-8 atm-cu m/mole(3) based upon its vapor pressure, 2.48X10-3 mm Hg(4), and water solubility, 5.8X10+4 mg/L(5). Triacetin is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(4). Utilizing the Japanese MITI test, 93% of the Theoretical BOD of a mixture containing triacetin was reached in 4 weeks(6) indicating that biodegradation is an important environmental fate process in soil(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 40(SRC), determined from a structure estimation method(2), indicates that triacetin is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 1.2X10-8 atm-cu m/mole(4) derived from its vapor pressure, 2.48X10-3 mm Hg(5), and water solubility, 5.8X10+4 mg/L(6). According to a classification scheme(7), an estimated BCF of 30(SRC), from its log Kow of 0.25(8) and a regression-derived equation(2), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Utilizing the Japanese MITI test, 93% of the Theoretical BOD of a mixture containing triacetin was reached in 4 weeks(9) indicating that biodegradation is an important environmental fate process in water(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), triacetin, which has a vapor pressure of 2.48X10-3 mm Hg at 25 °C(5), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase triacetin is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 4 days(SRC), calculated from its rate constant of 8.5X10-12 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Triacetin does not contain chromophores that absorb at wavelengths >290 nm(4) and, therefore, is not expected to be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Consumer Uses: Binder; Flavoring and nutrient; Solvent; Surfactant (surface active agent); Not Known or Reasonably Ascertainable; Plasticizer; Elasticizer; Fragrance; Adsorbent Source: EPA Chemical Data Reporting (CDR)
  • Industry Uses: Other; Binder; Solvent; Processing aids not otherwise specified; Surfactant (surface active agent); Reducing agent; Not Known or Reasonably Ascertainable; Fragrance; Plasticizer; Terminator/Blocker; Hardener Source: EPA Chemical Data Reporting (CDR)
  • Cosmetic Ingredient Review Link: CIR ingredient: Triacetin Source: Cosmetic Ingredient Review (CIR)
  • Sources/Uses: Used as cellulose plasticizer for cigarette filters; in binders for solid rocket fuels; as fixative in perfumes; to make cosmetics and pharmaceuticals; as solvent for celluloid and photographic films; to remove carbon dioxide from natural gas; and as topical antifungal medication; Technical triacetin (mixture of mono-, di-, and small quantities of triacetin) used as a solvent for basic dyes (especially indulines) and tannin in dyeing; [HSDB] Used in cigarette filters; Skin sensitization reported in a worker at a cigarette manufacturing plant; [Kanerva, p. 1841] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Photographic Processing [Category: Other] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: ... Primary use is as a cellulose plasticizer in the manufacture of cigarette filters, and its second largest use is as a component in binders for solid rocket fuels. Smaller amounts are used as a fixative in perfume, as a plasticizer for cellulose nitrate, in the manufacture of cosmetics, and as a carrier in fungicidal compositions. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Constituents of solid propellants: functions as inert plasticizer. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Fixative in perfumery; solvent in manufacturing celluloid, photographic films. Technical triacetin (a mixture of mono-, di-, and small quantities of triacetin) as a solvent for basic dyes, particularly indulines, and tannin in dyeing. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: To remove carbon dioxide from natural gas. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for TRIACETIN (11 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Plastics -> Typical concentration range in plastic materials -> 10% Source: NORMAN Suspect List Exchange

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TRIACETIN

INCI name

TRIACETIN

INN name

triacetin

Ph. Eur. name

glyceroli triacetas

Description

Triacetin

Record provenance

Inventory reference
38645
Imported identity
TRIACETIN
Source update
15/10/2010
European Commission CosIng source notes
Browse

Browse EU annexes

Explore Annex II–VI to see which substances are prohibited, restricted or permitted under specific conditions.

Search

Search annex entries

Search the annex database for entries matching TRIACETIN or related substances.

Key data

CAS
102-76-1
EC
203-051-9
Restriction
—
Function
ANTIMICROBIAL
Preventing and/or slowing down microbial growth.
FILM FORMING
Producing (upon application) a continuous film on the skin, hair or nails.
FRAGRANCE
Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.
PLASTICISER
Softening and making supple synthetic polymers that otherwise could not be easily deformed, spread or worked out.
SOLVENT
Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#29030 · TRIACETIN

Ingredients with overlapping formulation functions

TOSYLAMIDEPLASTICISER
TOSYLAMIDE/EPOXY RESINFILM FORMING, PLASTICISER
TOSYLAMIDE/FORMALDEHYDE RESINFILM FORMING, PLASTICISER
TRI-C14-15 ALKYL CITRATEPLASTICISER, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT
TRIBUTYL CITRATEFILM FORMING, PLASTICISER, SOLVENT
TRIBUTYLCRESYLBUTANEFILM FORMING, PLASTICISER, SOLVENT
TRICAPRYLYL/CAPRYL TRIMELLITATEPLASTICISER, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT
TRICETYL PHOSPHATEFILM FORMING, PLASTICISER

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How TRIACETIN appears in the CosIng inventory

The CosIng inventory lists TRIACETIN as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TRIACETIN is also tagged with 5 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TRIACETIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, TRIACETIN carries the following function designation(s):

CAS 102-76-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
View CAS records

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.
Open INCI Checker

Source note for TRIACETIN

This page reproduces the CosIng inventory entry for TRIACETIN from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research TRIACETIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sourcesView updates

Tools & next steps

Check your formula

Scan a full INCI list to detect TRIACETIN and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to TRIACETIN, its identifiers or nearby name variants.

Search