Is LIPASE safe to use in EU cosmetics?

LIPASE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 9001-62-1?

CAS 9001-62-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains LIPASE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 5729915/10/2010

LIPASE

Lipase is an enzyme that hydrolyzes triglycerides

LIPASE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 9001-62-1

CAS 9001-62-1PubChem CID 135534490

Lipase, triacylglycerol

IUPAC name: sodium 4-(pyridin-2-yldiazenyl)benzene-1,3-diol

Molecular formula: C11H9N3NaO2+
Molecular weight: 238.20 g/mol
Exact mass: 238.05924582 Da
Topological polar surface area: 78.1 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 5
Covalent units: 2
Defined stereocentres: 0

Also known as

Lipase AY 30sodium;4-(pyridin-2-yldiazenyl)benzene-1,3-diolLipase from Aspergillus oryzaeSEPHADEX G-50C11H9N3NaO2+lipase PS-IMLipase from Candida sp.4-(2-Pyridylazo)resorcinol disodium salt

16 more reported names

9014-49-7Deoxyribonucleic acids, thymusLipase from Rhizomucour mieheiLipase M from Mucor javanicusLipase A from Aspergillus nigerKZRPHCQLJZXMJV-UHFFFAOYSA-NDEA Sephadex A-25 Chloride FormLipase from Pseudomonas fluorescensLipase from Thermophila sparsiformisLipase G from Penicillium camembertiLipase PS, from Burkholderia cepaciaNSC-87878Lipoprotein Lipase,from burkholderia sp.1, 4-(2-pyridinylazo)-, disodium saltsodium;4-(2-pyridylazo)benzene-1,3-diolLipase acrylic resin pound recombinant pound(c)

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

PubMed:4564

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for LIPASE

INCI name

LIPASE

INN name

Rizolipase [USAN:INN]

Description

Lipase is an enzyme that hydrolyzes triglycerides

Record provenance

Inventory reference: 57299
Imported identity: LIPASE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for LIPASE

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Key data

CAS

9001-62-1

232-619-9

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#15452 · LIPASE

Ingredients with overlapping formulation functions

LINUM USITATISSIMUM HULL EXTRACTSKIN CONDITIONING

LINUM USITATISSIMUM SEED EXTRACTPERFUMING, SKIN CONDITIONING

LINUM USITATISSIMUM SEED OILPERFUMING, SKIN CONDITIONING

LINUM USITATISSIMUM SEED POWDERSKIN CONDITIONING

LIPPIA CITRIODORA FLOWER EXTRACTPERFUMING, SKIN CONDITIONING

LIPPIA CITRIODORA MERISTEM CELL CULTURESKIN CONDITIONING

LIQUIDAMBAR ACALYCINA/FORMOSANA RESIN OILFRAGRANCE, SKIN CONDITIONING

LIQUIDAMBAR FORMOSANA FRUIT EXTRACTSKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How LIPASE appears in the CosIng inventory

The CosIng inventory lists LIPASE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

LIPASE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

LIPASE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, LIPASE carries the following function designation(s):

SKIN CONDITIONING

CAS 9001-62-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for LIPASE

This page reproduces the CosIng inventory entry for LIPASE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research LIPASE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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