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CAS 16409-43-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 5678815/10/2010

ISOBUTENYL METHYLTETRAHYDROPYRAN

2H-Pyran, Tetrahydro-4-Methyl-2-(2-Methyl-1-Propenyl)-; Tetrahydro-4-methyl-2-(2-methylprop-1-enyl)pyran; rosenoxide; rosoxide

ISOBUTENYL METHYLTETRAHYDROPYRAN is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 16409-43-1

CAS 16409-43-1PubChem CID 27866

Rose oxide

Rose oxide is a member of the class of oxanes that is tetrahydro-2H-pyran which is substituted at positions 2 and 4 by an isoprop-1-enyl group and a methyl group, respectively. Organic compound of the pyran class and the monoterpene class and a fragrance found in roses and rose oil. All four possible stereoisomers are known; the 2S,4R and 2S,4S diastereoisomers [also known as the ()-cis- and ()-trans-isomers, respectively] are the main constituents in several essential oils and are used as a food flavouring and in perfumes and cosmetics. It has a role as a plant metabolite. It is a monoterpenoid, a member of oxanes and an olefinic compound. — ChEBI

IUPAC name: 4-methyl-2-(2-methylprop-1-enyl)oxane

Molecular formula: C10H18O
Molecular weight: 154.25 g/mol
Exact mass: 154.135765193 Da
XLogP3: 2.9
Topological polar surface area: 9.2 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 1
Covalent units: 1
Defined stereocentres: 0

Also known as

4-Methyl-2-(2-methylprop-1-en-1-yl)tetrahydro-2H-pyranRosenoxideRosoxideFEMA No. 3236Tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran2H-Pyran, tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-4-methyl-2-(2-methylprop-1-en-1-yl)oxanePyran, tetrahydro-4-methyl-2-(2-methylpropenyl)-

16 more reported names

2H-Pyran, tetrahydro-4-methyl-2-(2-methylpropenyl)-4-Methyl-2-(2-methyl-1-propenyl)tetrahydro-2H-pyranTetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyranCHEBI:900752-Isobutenyl-4-methyltetrahydropyran4O51437J50Tetrahydro-4-methyl-2-[2-methyl-1-propenyl]-2H-pyranrose-oxideRefChem:897131240-457-5(+)-Rose oxide2H-Pyran, tetrahydro-4-methyl-2-(2-methyl-1-propen-1-yl)-Tetrahydro-4-methyl-2-(2-methylprop-1-enyl)pyranPyran, 2-(2-methyl-1-propenyl)-4-methyltetrahydro-(-)-Rose oxidePYRAN, TETRAHYDRO-2-(2-METHYL-1-PROPENYL)-4-METHYL-

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:90075
EPA DTXSID:DTXSID1051771

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ISOBUTENYL METHYLTETRAHYDROPYRAN

INCI name

ISOBUTENYL METHYLTETRAHYDROPYRAN

Description

2H-Pyran, Tetrahydro-4-Methyl-2-(2-Methyl-1-Propenyl)-; Tetrahydro-4-methyl-2-(2-methylprop-1-enyl)pyran; rosenoxide; rosoxide

Record provenance

Inventory reference: 56788
Imported identity: ISOBUTENYL METHYLTETRAHYDROPYRAN
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for ISOBUTENYL METHYLTETRAHYDROPYRAN

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Key data

CAS

16409-43-1

240-457-5

Restriction

—

Function

FRAGRANCE: Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.
PERFUMING: Used for perfume and aromatic raw materials.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#13670 · ISOBUTENYL METHYLTETRAHYDROPYRAN

Ingredients with overlapping formulation functions

ISOAMYL ALLYLGLYCOLATEFRAGRANCE, PERFUMING

ISOAMYL CINNAMATEFRAGRANCE

ISOBORNYL ACETATEFRAGRANCE, PERFUMING

ISOBORNYLOXYETHANOLFRAGRANCE, SKIN CONDITIONING

ISOBUTYL BENZOATEFRAGRANCE, PRESERVATIVE, SOLVENT

ISOBUTYL METHYL TETRAHYDROPYRANOLFRAGRANCE

ISODON TRICHOCARPUS EXTRACTFRAGRANCE, SKIN CONDITIONING

ISODONIS JAPONICUS LEAF/STALK EXTRACTFRAGRANCE, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ISOBUTENYL METHYLTETRAHYDROPYRAN appears in the CosIng inventory

The CosIng inventory lists ISOBUTENYL METHYLTETRAHYDROPYRAN as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ISOBUTENYL METHYLTETRAHYDROPYRAN is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ISOBUTENYL METHYLTETRAHYDROPYRAN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ISOBUTENYL METHYLTETRAHYDROPYRAN carries the following function designation(s):

CAS 16409-43-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ISOBUTENYL METHYLTETRAHYDROPYRAN

This page reproduces the CosIng inventory entry for ISOBUTENYL METHYLTETRAHYDROPYRAN from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ISOBUTENYL METHYLTETRAHYDROPYRAN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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