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CAS 60046-25-5 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 5618615/10/2010

GLUCOHEPTONOLACTONE

D-Gluco-heptonic acid, gamma-lactone, (2csi)-

GLUCOHEPTONOLACTONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 60046-25-5

CAS 60046-25-5PubChem CID 108880

D-Glucoheptono-1,4-lactone

Additionally, the Panel concluded the available data are insufficient to make a determination that Glucoheptonolactone is safe under the intended conditions of use in cosmetic formulations. — Cosmetic Ingredient Review (CIR)

IUPAC name: (4S,5S)-3,4-dihydroxy-5-[(1R,2R)-1,2,3-trihydroxypropyl]oxolan-2-one

Molecular formula: C7H12O7
Molecular weight: 208.17 g/mol
Exact mass: 208.05830272 Da
XLogP3: -2.6
Topological polar surface area: 127.0 Å²
Hydrogen-bond donors: 5
Hydrogen-bond acceptors: 7
Covalent units: 1
Defined stereocentres: 4

Also known as

glucoheptonolactoneR320ILS1YQRefChem:1082882262-037-0UNII-R320ILS1YQEINECS 262-037-0(2.xi)-D-Gluco-heptono-gamma-lactoneD-gluco-heptono-?-lactone

5 more reported names

Glucoheptonic acid, ?-lactoneD-gluco-Heptonic acid, .gamma.-lactone, (2.xi.)-VIVCRCODGMFTFY-JPRIQSOUSA-ND-Glucoheptonic acid-1,4-lactoneGLUCOHEPTONIC ACID, .GAMMA.-LACTONE

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID301021206

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for GLUCOHEPTONOLACTONE

INCI name

GLUCOHEPTONOLACTONE

Description

D-Gluco-heptonic acid, gamma-lactone, (2csi)-

Record provenance

Inventory reference: 56186
Imported identity: GLUCOHEPTONOLACTONE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for GLUCOHEPTONOLACTONE

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Key data

CAS

60046-25-5

262-037-0

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#11000 · GLUCOHEPTONOLACTONE

Ingredients with overlapping formulation functions

GLOIOPELTIS FURCATA EXTRACTSKIN CONDITIONING

GLOIOPELTIS TENAX POWDERSKIN CONDITIONING

GLUCAROLACTONESKIN CONDITIONING

GLUCOHEPTONIC ACIDBUFFERING, SKIN CONDITIONING

GLUCOMANNANSKIN CONDITIONING, SKIN PROTECTING

GLUCONACETOBACTER XYLINUS FERMENT FILTRATE EXTRACTHUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

GLUCONOBACTER/HONEY FERMENT FILTRATEHAIR CONDITIONING, SKIN CONDITIONING

GLUCONOLACTONECHELATING, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How GLUCOHEPTONOLACTONE appears in the CosIng inventory

The CosIng inventory lists GLUCOHEPTONOLACTONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

GLUCOHEPTONOLACTONE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

GLUCOHEPTONOLACTONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, GLUCOHEPTONOLACTONE carries the following function designation(s):

SKIN CONDITIONING

CAS 60046-25-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for GLUCOHEPTONOLACTONE

This page reproduces the CosIng inventory entry for GLUCOHEPTONOLACTONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research GLUCOHEPTONOLACTONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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