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InventoryRef 5595015/10/2010

DIOXOLANE

1,3-Dioxolane

DIOXOLANE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 646-06-0
CAS 646-06-0PubChem CID 12586

1,3-Dioxolane

Dioxolane appears as a clear colorless liquid. Slightly denser than water. Vapors heavier than air. — CAMEO Chemicals

IUPAC name
1,3-dioxolane
Molecular formula
C3H6O2
Molecular weight
74.08 g/mol
Exact mass
74.036779430 Da
XLogP3
-0.4
Topological polar surface area
18.5 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

DIOXOLANEGlycolformal1,3-DioxacyclopentaneFormal glycol1,3-DioxolanEthylene glycol formalGlycol formalGlycol methylene ether
16 more reported names
1,3-Dioxole, dihydro-5-Crown-2Y57RBG19JLELCOTAL DXCHEBI:87597RefChem:72794CHEBI:39430211-463-51,3-Dioxolane, StabilizedEthylene glycol methylene ether1,3-Dioxolane (stabilized with BHT)1,3-DioxlaneDioxolan [Czech]1,3-dioxalaneCCRIS 4912Dioxolane, 1,3-
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DIOXOLANE

INCI name

DIOXOLANE

Description

1,3-Dioxolane

Record provenance

Inventory reference
55950
Imported identity
DIOXOLANE
Source update
15/10/2010
European Commission CosIng source notes
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Key data

CAS
646-06-0
EC
211-463-5
Restriction
—
Function
SOLVENT
Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#9128 · DIOXOLANE

Ingredients with overlapping formulation functions

DIMETHYL SUCCINATEFRAGRANCE, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT
DIMETHYL SULFONESOLVENT, VISCOSITY CONTROLLING
DIMETHYLOLCYCLOHEXANESOLVENT
DIOCTYLDODECYL SEBACATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT
DIPENTAERYTHRITYL PENTAISOSTEARATEBINDING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT
DIPHENYL METHANEFRAGRANCE, SOLVENT
DIPROPYL ADIPATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT
DIPROPYL OXALATECHELATING, PLASTICISER, SOLVENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How DIOXOLANE appears in the CosIng inventory

The CosIng inventory lists DIOXOLANE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DIOXOLANE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DIOXOLANE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, DIOXOLANE carries the following function designation(s):

CAS 646-06-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for DIOXOLANE

This page reproduces the CosIng inventory entry for DIOXOLANE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research DIOXOLANE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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