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CAS 108-16-7 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 5592215/10/2010

DIMETHYL ISOPROPANOLAMINE

1-(dimethylamino)propan-2-ol

DIMETHYL ISOPROPANOLAMINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 108-16-7

CAS 108-16-7PubChem CID 37511

Dimepranol

IUPAC name: 1-(dimethylamino)propan-2-ol

Molecular formula: C5H13NO
Molecular weight: 103.16 g/mol
Exact mass: 103.099714038 Da
XLogP3: 0.0
Topological polar surface area: 23.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

1-(Dimethylamino)-2-propanolDimethylisopropanolamineN,N-DimethylisopropanolamineDimethyl(2-hydroxypropyl)amine2-PROPANOL, 1-(DIMETHYLAMINO)-Dimepranol [INN]N,N-Dimethyl-2-hydroxypropylamineDimepranolum

16 more reported names

N,N-(Dimethylamino)-2-propanol1,1-Dimethylaminopropanol-22-Propanol, 1,1-(dimethylamino)-Dimepranolum [INN-Latin]NSC 31632-(Dimethylamino)-1-methylethanolEINECS 203-556-4n,n-dimethylamino-2-propanolBRN 1209244AI3-18202dimethyl isopropanolamineNSC-3163EXTENDEX 503-(DIMETHYLAMINO)-2-PROPANOLDMA-2PEC 203-556-4

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL3186209
EPA DTXSID:DTXSID5031210
PubMed:22906572
PubMed:22111927
PubMed:20812744
PubMed:12357411

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match37511

Attributed physical-property, hazard, environmental and use annotations.

Physical Description: Liquid Source: EPA Chemical Data Reporting (CDR)

Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
GHS Hazard Statements: H226: Flammable liquid and vapor [Warning Flammable liquids]; H302: Harmful if swallowed [Warning Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P260, P264, P270, P280, P301+P317, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P330, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
Signal: Danger Source: European Chemicals Agency (ECHA)
GHS Hazard Statements: H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]; H302+H312 (51.4%): Harmful if swallowed or in contact with skin [Warning Acute toxicity, oral; acute toxicity, dermal]; H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]; H312 (59.4%): Harmful in contact with skin [Warning Acute toxicity, dermal]; H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318 (39.5%): Causes serious eye damage [Danger Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P260, P264, P264+P265, P270, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
ECHA C&L Notifications Summary: Aggregated GHS information provided per 276 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
GHS Hazard Statements: H226: Flammable liquid and vapor [Warning Flammable liquids]; H302: Harmful if swallowed [Warning Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P260, P264, P270, P280, P301+P317, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P330, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia

Industry Uses: Intermediate; Surface modifier Source: EPA Chemical Data Reporting (CDR)

Uses: Use (kg; approx.) in Germany (2009): >50; Consumption (g per capita; approx.) in Germany (2009): 0.000611; Calculated removal (%): 75.1 Source: NORMAN Suspect List Exchange

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DIMETHYL ISOPROPANOLAMINE

INCI name

DIMETHYL ISOPROPANOLAMINE

INN name

dimepranol

Description

1-(dimethylamino)propan-2-ol

Record provenance

Inventory reference: 55922
Imported identity: DIMETHYL ISOPROPANOLAMINE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for DIMETHYL ISOPROPANOLAMINE

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Key data

CAS

108-16-7

203-556-4

Restriction

—

Function

BUFFERING: Stabilising the pH of an aqueous medium in a narrow range even if an acid or base is added. Altering and/or maintaining a cosmetic product's pH at the desired level.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#8973 · DIMETHYL ISOPROPANOLAMINE

Ingredients with overlapping formulation functions

DIETHYLAMINEBUFFERING, FRAGRANCE, PERFUMING

DIHYDROXYACETIC ACIDANTISTATIC, BUFFERING, HAIR WAVING OR STRAIGHTENING

DIISOPROPANOLAMINEBUFFERING

DIISOPROPYLAMINEBUFFERING

DIMETHYL MEABUFFERING

DIMETHYLGLUCAMINEBUFFERING

DIOLEOYL EDETOLMONIUM METHOSULFATEANTISTATIC, BUFFERING, HAIR CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

DIOLEYL PHOSPHATEBUFFERING, EMULSION STABILISING, HAIR CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How DIMETHYL ISOPROPANOLAMINE appears in the CosIng inventory

The CosIng inventory lists DIMETHYL ISOPROPANOLAMINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DIMETHYL ISOPROPANOLAMINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DIMETHYL ISOPROPANOLAMINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, DIMETHYL ISOPROPANOLAMINE carries the following function designation(s):

BUFFERING

CAS 108-16-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for DIMETHYL ISOPROPANOLAMINE

This page reproduces the CosIng inventory entry for DIMETHYL ISOPROPANOLAMINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research DIMETHYL ISOPROPANOLAMINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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