What does the restriction note for ACID BLUE 74 ALUMINUM LAKE mean?

The restriction field for ACID BLUE 74 ALUMINUM LAKE reads: IV/99. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 16521-38-3?

CAS 16521-38-3 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains ACID BLUE 74 ALUMINUM LAKE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 5415618/10/2010

ACID BLUE 74 ALUMINUM LAKE

2-(1,3-Dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-1H-indole-5-sulfonic acid aluminium complex (CI 73015)

ACID BLUE 74 ALUMINUM LAKE is linked to 1 EU annex record on this page. Inventory note: IV/99.

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Market	Evidence status	Records	Source language
European Union	Evidence linked Positive-list entry with conditions Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 16521-38-3

CAS 16521-38-3PubChem CID 61842

C.I. Pigment Blue 63

C.I. Pigment Blue 63 is a member of hydroxyindoles. — ChEBI

IUPAC name: aluminum 2-(3-hydroxy-5-sulfo-1H-indol-2-yl)-3-oxoindole-5-sulfonic acid

Molecular formula: C16H10AlN2O8S2+3
Molecular weight: 449.4 g/mol
Exact mass: 448.9693960 Da
Topological polar surface area: 191.0 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 9
Covalent units: 2
Defined stereocentres: 0

Also known as

RefChem:572495C.I. Food Blue 1-aluminum lake1342-11-6Certolake indigo carmineIndigotine-aluminum lakealuminum;2-(3-hydroxy-5-sulfo-1H-indol-2-yl)-3-oxoindole-5-sulfonic acidC.I. Food Blue 1:1Indigo carmine-aluminum lake

16 more reported names

Japan Blue 2 Aluminum lakeAcid Blue 74-aluminum lakeJapan Food Blue No. 2 aluminum lakeC.I. 73015 Aluminum lakeC.I. 73015-Aluminum lakeFood Blue No. 2-aluminum lakeC.I. Acid Blue 74-aluminum lakeEINECS 240-589-3Indigo disulfonic acid, aluminum saltFD&C Blue No. 2-aluminum lakeAluminum 3,3'-dioxo-(delta2,2-biindoline)-5,5'disulfonate(delta2,2-Biindoline)-5,5'-disulfonic acid, 3,3'-dioxo-, aluminum saltCHEBI:172686INHYHTBURMMHBG-UHFFFAOYSA-NPigment Blue 63 (Food Blue 1:1)(Z)-3,3'-dioxo-[2,2'-biindolinylidene]-5,5'-disulfonic acid, aluminum(III) salt

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:172686

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ACID BLUE 74 ALUMINUM LAKE

INCI name

ACID BLUE 74 ALUMINUM LAKE

Description

2-(1,3-Dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-1H-indole-5-sulfonic acid aluminium complex (CI 73015)

Record provenance

Inventory reference: 54156
Imported identity: ACID BLUE 74 ALUMINUM LAKE
Source update: 18/10/2010

European Commission CosIng source notes

Annex records for ACID BLUE 74 ALUMINUM LAKE

Annex IV Restriction reference

Entry 99

CI 73015

CAS: 860-22-0

EC: 212-728-8

Key data

CAS

16521-38-3

240-589-3

Restriction

IV/99

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#848 · ACID BLUE 74 ALUMINUM LAKE

Ingredients with overlapping formulation functions

ACID BLUE 1HAIR DYEING

ACID BLUE 3HAIR DYEING

ACID BLUE 62COLORANT, HAIR DYEING

ACID BLUE 74HAIR DYEING

ACID BLUE 9HAIR DYEING

ACID BLUE 9 ALUMINUM LAKEHAIR DYEING

ACID BLUE 9 AMMONIUM SALTHAIR DYEING

ACID BROWN 13HAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ACID BLUE 74 ALUMINUM LAKE appears in the CosIng inventory

The CosIng inventory lists ACID BLUE 74 ALUMINUM LAKE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ACID BLUE 74 ALUMINUM LAKE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ACID BLUE 74 ALUMINUM LAKE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for ACID BLUE 74 ALUMINUM LAKE reads: "IV/99". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, ACID BLUE 74 ALUMINUM LAKE carries the following function designation(s):

HAIR DYEING

CAS 16521-38-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ACID BLUE 74 ALUMINUM LAKE

This page combines the CosIng inventory entry for ACID BLUE 74 ALUMINUM LAKE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research ACID BLUE 74 ALUMINUM LAKE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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