What does the restriction note for ROSE KETONE-3 mean?

The restriction field for ROSE KETONE-3 reads: III/161. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 57378-68-4?

CAS 57378-68-4 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains ROSE KETONE-3?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 4149115/10/2010

ROSE KETONE-3

1-(2,6,6-Trimethyl-3-cyclohexenyl)-2-buten-1-one

ROSE KETONE-3 is linked to 1 EU annex record on this page. Inventory note: III/161.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Restricted entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 57378-68-4

CAS 57378-68-4PubChem CID 5365916

Delta-Damascone

IUPAC name: (E)-1-(2,6,6-trimethylcyclohex-3-en-1-yl)but-2-en-1-one

Molecular formula: C13H20O
Molecular weight: 192.30 g/mol
Exact mass: 192.151415257 Da
XLogP3: 3.4
Topological polar surface area: 17.1 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 1
Covalent units: 1
Defined stereocentres: 0

Also known as

8-DamasconeDelta Damascone.delta.-DamasconeFEMA No. 3622trans-delta-damascone2-BUTEN-1-ONE, 1-(2,6,6-TRIMETHYL-3-CYCLOHEXEN-1-YL)-EINECS 275-156-87F4RIE5P7E

16 more reported names

DAMASCONE, .DELTA.-(2E)-1-(2,6,6-trimethylcyclohex-3-en-1-yl)but-2-en-1-oneDELTA-DAMASCONE [USP-RS].DELTA.-DAMASCONE [FHFI]Damascone, delta-BRN 1939321EINECS 260-709-8(E)-1-(2beta,6,6-Trimethyl-3-cyclohexen-1alpha-yl)-2-butene-1-one2-Buten-1-one, 1-(2,6,6-trimethyl-3-cyclohexen-1-yl)-, (2E)-DELTA-DAMASCONE (USP-RS)2-Buten-1-one, 1-(2,6,6-trimethyl-3-cyclohexen-1-yl)-, (1alpha(E),2beta)-RefChem:585682DELTA-DAMASCONE [INCI]2-Buten-1-one, 1-(2,6,6-trimethyl-3-cyclohexen-1-yl)-, [1.alpha.(E),2.beta.]-260-709-81-(2,6,6-trimethyl-3-cyclohexen-1-yl)-2-buten-1-one

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL4514620
EPA DTXSID:DTXSID101366620

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ROSE KETONE-3

INCI name

ROSE KETONE-3

Description

1-(2,6,6-Trimethyl-3-cyclohexenyl)-2-buten-1-one

Record provenance

Inventory reference: 41491
Imported identity: ROSE KETONE-3
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for ROSE KETONE-3

Annex III Shared CAS number

Entry 157

Alpha-Damascone/cis-Rose ketone 1/trans-Rose ketone 1; Rose ketone 4 (Damascone); Rose ketone 3 (de…

CAS: 43052-87-5/ 23726-94-5/24720-09-0; 23696-85-7; 57378-68-4/ 71048-82-3; 23726-92-3; 23726-91-2

EC: -/ 245-845-8/ 246-430-4; 245-833-2; 260-709-8/ 275-156-8; 245-843-7; 245-842-1

Key data

CAS

57378-68-4

260-709-8

Restriction

III/161

Function

PERFUMING: Used for perfume and aromatic raw materials.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#24600 · ROSE KETONE-3

Records sharing a CAS or EC identity

DELTA-DAMASCONE

Ingredients with overlapping formulation functions

ROSA GALLICA FLOWER WATERFLAVOURING, FRAGRANCE, PERFUMING

ROSA INDICA FLOWER EXTRACTANTIOXIDANT, FLAVOURING, FRAGRANCE, PERFUMING

ROSA MOSCHATA FLOWER OILFRAGRANCE; PERFUMING

ROSA RUGOSA FLOWER WATERFRAGRANCE, PERFUMING

ROSE KETONE-4PERFUMING

ROSE KETONE-5PERFUMING

ROSMARINUS OFFICINALIS FLOWER EXTRACTANTIOXIDANT, DEODORANT, PERFUMING, SKIN CONDITIONING

ROSMARINUS OFFICINALIS FLOWER OILPERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ROSE KETONE-3 appears in the CosIng inventory

The CosIng inventory lists ROSE KETONE-3 as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ROSE KETONE-3 is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ROSE KETONE-3 appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for ROSE KETONE-3 reads: "III/161". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, ROSE KETONE-3 carries the following function designation(s):

PERFUMING

CAS 57378-68-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ROSE KETONE-3

This page combines the CosIng inventory entry for ROSE KETONE-3 with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research ROSE KETONE-3 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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