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CAS 14667-55-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 4124402/03/2011

TRIMETHYLPYRAZINE

2,3,5-Trimethylpyrazine

TRIMETHYLPYRAZINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 14667-55-1

CAS 14667-55-1PubChem CID 26808

Trimethylpyrazine

Trimethylpyrazine is a member of the class of pyrazines that is pyrazine in which three hydrogens at positions 2, 3 and 5 have been replaced by methyl groups. It has a role as a pheromone, a flavouring agent, an animal metabolite, a plant metabolite and a bacterial metabolite. — ChEBI

IUPAC name: 2,3,5-trimethylpyrazine

Molecular formula: C7H10N2
Molecular weight: 122.17 g/mol
Exact mass: 122.084398327 Da
XLogP3: 1.0
Topological polar surface area: 25.8 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

Pyrazine, trimethyl-2,3,5-Trimethyl pyrazine2,3,6-TrimethylpyrazineFEMA No. 3244Q8PR0W8TITCHEBI:190131RefChem:441845238-712-0

16 more reported names

Pyrazine, 2,3,5-trimethyl-Trimethyl-pyrazinetrimethyl pyrazinePyrazine, 2,3,5-trimethylCCRIS 2932EINECS 238-712-0UNII-Q8PR0W8TIT2,3,5-Trimethyl pyrazine (natural)BRN 0002423AI3-344422,3,5-Trimethyl-pyrazineFEMA 32442,3,5-Trimethylpyrazine, 99%Tox21_302314MSK1797-1000MCS-W011192

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:190131
ChEMBL:CHEMBL320146
EPA DTXSID:DTXSID1047075
PubMed:22988937
PubMed:22972787
PubMed:22541463
PubMed:22463717
PubMed:22417522
PubMed:21535747
PubMed:20492142
PubMed:20170168
PubMed:20122694
PubMed:20121201
PubMed:19771358
PubMed:19569109

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TRIMETHYLPYRAZINE

INCI name

TRIMETHYLPYRAZINE

Description

2,3,5-Trimethylpyrazine

Record provenance

Inventory reference: 41244
Imported identity: TRIMETHYLPYRAZINE
Source update: 02/03/2011

European Commission CosIng source notes

Annex records for TRIMETHYLPYRAZINE

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Key data

CAS

14667-55-1

238-712-0

Restriction

—

Function

PERFUMING: Used for perfume and aromatic raw materials.

Ingredients with overlapping formulation functions

TRIMETHYLHEXYL PROPIONATEPERFUMING

TRIMETHYLNORBORNAN-2-ONEPERFUMING

TRIMETHYLPENTADECATRIEN-2-ONEPERFUMING

TRIMETHYLPHENETHYL ALCOHOLPERFUMING

TRIMETHYLTRICYCLODODECANOLPERFUMING

TRIMETHYLTRICYCLODODECANYL ACETATEPERFUMING

TRIMETHYLTRICYCLODODECANYL FORMATEPERFUMING

TRIMETHYLUNDECADIENALPERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How TRIMETHYLPYRAZINE appears in the CosIng inventory

The CosIng inventory lists TRIMETHYLPYRAZINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TRIMETHYLPYRAZINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TRIMETHYLPYRAZINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, TRIMETHYLPYRAZINE carries the following function designation(s):

PERFUMING

CAS 14667-55-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for TRIMETHYLPYRAZINE

This page reproduces the CosIng inventory entry for TRIMETHYLPYRAZINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research TRIMETHYLPYRAZINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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