Is TIGLIC ACID safe to use in EU cosmetics?

TIGLIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 80-59-1?

CAS 80-59-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains TIGLIC ACID?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 4113602/03/2011

TIGLIC ACID

(E)-2-Methylbut-2-enoic Acid

TIGLIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 80-59-1

CAS 80-59-1PubChem CID 125468

Tiglic acid

Tiglic acid, [corrosive solid] appears as a white lustrous flaked solid with a fruity or spicy odor. About the same density as water and slightly soluble in water. May burn if heated to high temperatures. May severely irritate skin, eyes, lungs or mucous membranes. — CAMEO Chemicals

IUPAC name: (E)-2-methylbut-2-enoic acid

Molecular formula: C5H8O2
Molecular weight: 100.12 g/mol
Exact mass: 100.052429494 Da
XLogP3: 1.0
Topological polar surface area: 37.3 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

Tiglinic acidtrans-2,3-Dimethylacrylic acidtrans-2-Methyl-2-butenoic acidtrans-2-Methylcrotonic acid(E)-2,3-Dimethylacrylic acid(E)-2-Methyl-2-butenoic acid(E)-2-Methylcrotonic acid2-Butenoic acid, 2-methyl-, (2E)-

16 more reported names

Crotonic acid, 2-methyl-, (E)-2-Butenoic acid, 2-methyl-, (E)-2,3-Dimethylacrylic acid, (E)-FEMA No. 3599trans-alpha,beta-Dimethylacrylic acid2-methyl-2E-butenoic acidI5792N03HCNSC-8999NSC-44235CHEBI:9592RefChem:25822(e)-alpha-methylcrotonic acid201-295-0Cevadic acid2-Methyl-2-butenoic acid2-methylbut-2-enoic acid

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:36432
ChEBI:CHEBI:9592
ChEMBL:CHEMBL52416
EPA DTXSID:DTXSID80883257
PubMed:21220428

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TIGLIC ACID

INCI name

TIGLIC ACID

Description

(E)-2-Methylbut-2-enoic Acid

Record provenance

Inventory reference: 41136
Imported identity: TIGLIC ACID
Source update: 02/03/2011

European Commission CosIng source notes

Annex records for TIGLIC ACID

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Key data

CAS

80-59-1

201-295-0

Restriction

—

Function

PERFUMING: Used for perfume and aromatic raw materials.

Ingredients with overlapping formulation functions

THYMUS VULGARIS EXTRACTPERFUMING, SKIN CONDITIONING

THYMUS VULGARIS FLOWER/LEAF/STEM WATERFRAGRANCE, PERFUMING

THYMUS VULGARIS OILFRAGRANCE, PERFUMING

THYMUS ZYGIS HERB EXTRACTPERFUMING

TILIA AMERICANA FLOWER OILFLAVOURING, FRAGRANCE, PERFUMING

TOLUALDEHYDE ISOMERSPERFUMING

TRANS, TRANS-2,4-DECADIENALPERFUMING

TRANS, TRANS-NONA-2,4-DIENALPERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How TIGLIC ACID appears in the CosIng inventory

The CosIng inventory lists TIGLIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TIGLIC ACID is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TIGLIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, TIGLIC ACID carries the following function designation(s):

PERFUMING

CAS 80-59-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for TIGLIC ACID

This page reproduces the CosIng inventory entry for TIGLIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research TIGLIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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