What does the restriction note for METHYL 2-OCTYNOATE mean?

The restriction field for METHYL 2-OCTYNOATE reads: III/89. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 111-12-6?

CAS 111-12-6 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains METHYL 2-OCTYNOATE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 4069215/10/2010

METHYL 2-OCTYNOATE

Methyl Oct-2-ynoate; methyl heptine carbonate

METHYL 2-OCTYNOATE is linked to 1 EU annex record on this page. Inventory note: III/89.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Restricted entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Restricted Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Restricted Open this evidence	1	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Restricted Open this evidence	1	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Evidence linked Restricted Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Restricted Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 111-12-6

CAS 111-12-6PubChem CID 8092

Methyl 2-octynoate

Methyl 2-octynoate is a fatty acid ester. — ChEBI

IUPAC name: methyl oct-2-ynoate

Molecular formula: C9H14O2
Molecular weight: 154.21 g/mol
Exact mass: 154.099379685 Da
XLogP3: 3.2
Topological polar surface area: 26.3 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

Methyl heptine carbonateFolioneMethyl 2-octynate2-OCTYNOIC ACID, METHYL ESTERVert de violette, artificialMethyl hept-1-yne-1-carboxylateMethyl pentylacetylenecarboxylateFEMA No. 2729

16 more reported names

0TTP6YT2T3NSC-72098RefChem:817769203-836-6Methyl 2-octinateNSC 720982-Octynoic Acid Methyl EsterMethyl heptyne carbonateMethyloct-2-ynoate2-Octynoic acid-methyl esterCS-W0142922-Octynoic acid-methyl ester 1000 microg/mL in AcetonitrileCAS-111-12-6Octynoic acid, methyl esterEN300-787196EINECS 203-836-6

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:168485
ChEMBL:CHEMBL3185035
EPA DTXSID:DTXSID9047093
PubMed:26795242
PubMed:22023385
PubMed:20495907
PubMed:20136892
PubMed:17162413
PubMed:12010023

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match8092

Attributed physical-property, hazard, environmental and use annotations.

Boiling Point: 217.00 to 220.00 °C. @ 760.00 mm Hg Source: Human Metabolome Database (HMDB)
Boiling Point: 215-217 °C Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)

Density: 0.919-0.924 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)

Physical Description: Colourless to slightly yellow liquid; Powerful, unpleasant odour. Violet like when diluted. Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)

Refractive Index: 1.443-1.449 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)

Solubility: Soluble in most fixed oils; Slightly soluble in propylene glycol; Insoluble in water, glycerin Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Solubility: Soluble (in ethanol) Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)

Signal: Warning Source: European Chemicals Agency (ECHA)
GHS Hazard Statements: H302 (97.3%): Harmful if swallowed [Warning Acute toxicity, oral]; H317 (97.4%): May cause an allergic skin reaction [Warning Sensitization, Skin] Source: European Chemicals Agency (ECHA)
Precautionary Statement Codes: P261, P264, P270, P272, P280, P301+P317, P302+P352, P321, P330, P333+P317, P362+P364, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
ECHA C&L Notifications Summary: Aggregated GHS information provided per 1763 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
Signal: Warning Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
GHS Hazard Statements: H317: May cause an allergic skin reaction [Warning Sensitization, Skin] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
Precautionary Statement Codes: P261, P272, P280, P302+P352, P321, P333+P317, P362+P364, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for METHYL 2-OCTYNOATE

INCI name

METHYL 2-OCTYNOATE

Description

Methyl Oct-2-ynoate; methyl heptine carbonate

Record provenance

Inventory reference: 40692
Imported identity: METHYL 2-OCTYNOATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for METHYL 2-OCTYNOATE

Annex III Restriction reference

Entry 89

Methyl 2-Octynoate

CAS: 111-12-6

EC: 203-836-6

Key data

CAS

111-12-6

203-836-6

Restriction

III/89

Function

PERFUMING: Used for perfume and aromatic raw materials.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#16451 · METHYL 2-OCTYNOATE

Declared fragrance allergen

This substance is on the EU list of fragrance allergens that must be named individually in the ingredient list, rather than being covered by the word "parfum", once it exceeds 0.001% in a leave-on product or 0.01% in a rinse-off product.

Declaration is a labelling duty under Article 19, not a restriction on use. See the allergen record

Ingredients with overlapping formulation functions

METHOXYTRIDECENEPERFUMING

METHOXYTRIMETHYLHEPTANOLFRAGRANCE, PERFUMING

METHYL 2,6,10-TRIMETHYLCYCLODODECA-2,5,9-TRIENYL KETONEPERFUMING

METHYL 2,6,6-TRIMETHYLCYCLOHEX-2-ENECARBOXYLATEPERFUMING

METHYL 3-NONENOATEPERFUMING

METHYL 3-OXO-2-PENTENYLCYCLOPENTANEACETATEPERFUMING

METHYL 3-OXO-PENTENYL-CYCLOPENTANEACETATEPERFUMING

METHYL 4-T-BUTYLBENZOATEFLAVOURING, FRAGRANCE, PERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How METHYL 2-OCTYNOATE appears in the CosIng inventory

The CosIng inventory lists METHYL 2-OCTYNOATE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

METHYL 2-OCTYNOATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

METHYL 2-OCTYNOATE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for METHYL 2-OCTYNOATE reads: "III/89". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, METHYL 2-OCTYNOATE carries the following function designation(s):

PERFUMING

CAS 111-12-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for METHYL 2-OCTYNOATE

This page combines the CosIng inventory entry for METHYL 2-OCTYNOATE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research METHYL 2-OCTYNOATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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