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InventoryRef 4060202/03/2011

PHENETHYL ISOBUTYRATE

Phenylethyl 2-methylpropanoate

PHENETHYL ISOBUTYRATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 103-48-0
CAS 103-48-0PubChem CID 7655

Phenethyl isobutyrate

Phenethyl isobutyrate is a carboxylic ester obtained by the formal condensation of 2-phenylethanol with isobutyric acid. It has a role as a metabolite. It is functionally related to an isobutyric acid and a 2-phenylethanol. — ChEBI

IUPAC name
2-phenylethyl 2-methylpropanoate
Molecular formula
C12H16O2
Molecular weight
192.25 g/mol
Exact mass
192.115029749 Da
XLogP3
3.3
Topological polar surface area
26.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

2-Phenylethyl isobutyratePhenylethyl isobutyrateBenzylcarbinol isobutyrateBenzylcarbinyl isobutyratePhenethyl 2-methylpropanoatePhenethyl 2-methylpropionateISOBUTYRIC ACID, PHENETHYL ESTER2-Phenylethyl 2-methylpropionate
16 more reported names
beta-Phenylethyl isobutyratePropanoic acid, 2-methyl-, 2-phenylethyl esterFEMA No. 2862Benzylcarbinyl 2-methylpropanoate2-Phenylethyl isobutanoatePhenylethyl 2-methylpropanoateAI3-18545QRZ4RE7DCL.beta.-Phenylethyl isobutyrateCHEBI:87409PHENETHYL ISOBUTYRATE [FCC]Isobutyric Acid 2-Phenylethyl EsterCAS-103-48-0Isobutyric acid phenethyl esterPhenethylisobutyratePhenethyl isobutyrate (natural)
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:87409

phenethyl isobutyrate

A carboxylic ester obtained by the formal condensation of 2-phenylethanol with isobutyric acid.

Formula
C12H16O2
Average mass
192.258 g/mol
Monoisotopic mass
192.11503 Da
Formal charge
0
  • carboxylic ester — is a (CHEBI:33308)
  • metabolite — has role (CHEBI:25212)
  • 2-phenylethanol — has functional parent (CHEBI:49000)
  • isobutyric acid — has functional parent (CHEBI:16135)
  • metabolite — has role (CHEBI:25212)
  • carboxylic ester — is a (CHEBI:33308)
Additional curated names
2-phenylethyl 2-methylpropanoatebenzylcarbinol isobutyratebeta-phenylethyl isobutyrate
Cross-references from this source
  • CAS: 103-48-0 — ChemIDplus
  • CAS: 103-48-0 — NIST Chemistry WebBook
  • REGISTRY_NUMBER: 2330243 — Reaxys

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2015-08-28. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match7655

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for > 99.9% (1663 of 1664) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 1663 of 1664 companies (only < 0.1% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 1664 reports by companies from 3 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 1663 of 1664 reports by companies.; There is 1 notification provided by 1 of 1664 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for PHENETHYL ISOBUTYRATE

INCI name

PHENETHYL ISOBUTYRATE

Description

Phenylethyl 2-methylpropanoate

Record provenance

Inventory reference
40602
Imported identity
PHENETHYL ISOBUTYRATE
Source update
02/03/2011
European Commission CosIng source notes
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Key data

CAS
103-48-0
EC
203-116-1
Restriction
—
Function
PERFUMING
Used for perfume and aromatic raw materials.

Ingredients with overlapping formulation functions

PHENETHYL BUTYRATEPERFUMING
PHENETHYL CINNAMATEPERFUMING
PHENETHYL CROTONATEPERFUMING
PHENETHYL FORMATEPERFUMING
PHENETHYL ISOTHIOCYANATEPERFUMING
PHENETHYL ISOVALERATEPERFUMING
PHENETHYL METHACRYLATEPERFUMING
PHENETHYL METHYL ETHYL CARBINOLPERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How PHENETHYL ISOBUTYRATE appears in the CosIng inventory

The CosIng inventory lists PHENETHYL ISOBUTYRATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PHENETHYL ISOBUTYRATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PHENETHYL ISOBUTYRATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, PHENETHYL ISOBUTYRATE carries the following function designation(s):

CAS 103-48-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for PHENETHYL ISOBUTYRATE

This page reproduces the CosIng inventory entry for PHENETHYL ISOBUTYRATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research PHENETHYL ISOBUTYRATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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