Is HIBISCOLIDE safe to use in EU cosmetics?

HIBISCOLIDE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 6707-60-4?

CAS 6707-60-4 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains HIBISCOLIDE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 4025302/03/2011

HIBISCOLIDE

12-Oxahexadecan-16-olide

HIBISCOLIDE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 6707-60-4

CAS 6707-60-4PubChem CID 23173

1,6-Dioxacycloheptadecan-7-one

IUPAC name: 1,6-dioxacycloheptadecan-7-one

Molecular formula: C15H28O3
Molecular weight: 256.38 g/mol
Exact mass: 256.20384475 Da
XLogP3: 4.2
Topological polar surface area: 35.5 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

12-OxahexadecanolideCervolide12-Oxa-1,16-hexadecanolideG6U2GR91JIUndecanoic acid, 11-(4-hydroxybutoxy)-, omicron-lactoneNSC-34741RefChem:78283229-755-6

16 more reported names

Hibiscolide12-Oxahexadecan-16-olideUNII-G6U2GR91JIEINECS 229-755-6NSC 34741BRN 01588021,6-DIOXACYCLOHEPTADECAN-17-ONE16-Hydroxy-12 oxahexadecanoic acid, omega-lactone16-Hydroxy-12-oxahexadecanoic acid, omega-lactone5-19-04-00070 (Beilstein Handbook Reference)Musk 78112-oxa-hexadecanolideOprea1_119748Oprea1_3182612,7-dioxacycloheptadecan-1-one12-oxahexadecanolide, AldrichCPR

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL3186263
EPA DTXSID:DTXSID4047705
PubMed:21801790
PubMed:11408205

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for HIBISCOLIDE

INCI name

HIBISCOLIDE

Description

12-Oxahexadecan-16-olide

Record provenance

Inventory reference: 40253
Imported identity: HIBISCOLIDE
Source update: 02/03/2011

European Commission CosIng source notes

Annex records for HIBISCOLIDE

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Key data

CAS

6707-60-4

229-755-6

Restriction

—

Function

PERFUMING: Used for perfume and aromatic raw materials.

Ingredients with overlapping formulation functions

HEXYLDIHYDROFURANONEPERFUMING

HEXYLENE GLYCOLPERFUMING, SKIN CONDITIONING, SOLVENT, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

HEXYLETHYLIDENEAMINO-BENZOATEPERFUMING

HEXYLOXYACETALDEHYDE DIMETHYL ACETALPERFUMING

HIBISCUS ABELMOSCHUS FLOWER/SEED WATERFLAVOURING, FRAGRANCE, PERFUMING, SKIN CONDITIONING

HIBISCUS ABELMOSCHUS SEED EXTRACTFRAGRANCE, PERFUMING, SKIN CONDITIONING

HIBISCUS ABELMOSCHUS SEED OILFRAGRANCE, PERFUMING

HIEROCHLOE ALPINA HERB EXTRACTPERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How HIBISCOLIDE appears in the CosIng inventory

The CosIng inventory lists HIBISCOLIDE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HIBISCOLIDE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HIBISCOLIDE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, HIBISCOLIDE carries the following function designation(s):

PERFUMING

CAS 6707-60-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for HIBISCOLIDE

This page reproduces the CosIng inventory entry for HIBISCOLIDE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research HIBISCOLIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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