Is MADROX safe to use in EU cosmetics?

MADROX is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 37514-30-0?

CAS 37514-30-0 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains MADROX?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 4004402/03/2011

MADROX

1-Methoxy-1-methylcyclododecane

MADROX is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 37514-30-0

CAS 37514-30-0PubChem CID 161949

Cyclododecane, 1-methoxy-1-methyl-

IUPAC name: 1-methoxy-1-methylcyclododecane

Molecular formula: C14H28O
Molecular weight: 212.37 g/mol
Exact mass: 212.214015512 Da
XLogP3: 5.3
Topological polar surface area: 9.2 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 1
Covalent units: 1
Defined stereocentres: 0

Also known as

Madrox1-Methylcyclododecyl methyl ether1-Methyl-1-methoxycyclododecaneEINECS 253-534-3BRN 2238172RefChem:129449253-534-3amber dodecane

2 more reported names

FJ62QR3MEQQACBYNLZEUNZSC-UHFFFAOYSA-N

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID4068034

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for MADROX

INCI name

MADROX

Description

1-Methoxy-1-methylcyclododecane

Record provenance

Inventory reference: 40044
Imported identity: MADROX
Source update: 02/03/2011

European Commission CosIng source notes

Annex records for MADROX

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Key data

CAS

37514-30-0

253-534-3

Restriction

—

Function

PERFUMING: Used for perfume and aromatic raw materials.

Ingredients with overlapping formulation functions

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M-TOLUALDEHYDEPERFUMING

M-TOLYL PHENYLACETATEPERFUMING

MAGNOLIA GLAUCA FLOWER WATERFRAGRANCE, PERFUMING

MALTOL ISOBUTYRATEFRAGRANCE, PERFUMING, TONIC

MALUS DOMESTICA FRUIT WATER EXTRACTSKIN CONDITIONING - EMOLLIENT; FRAGRANCE; PERFUMING

MANGIFERA INDICA PEEL EXTRACTFRAGRANCE; PERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How MADROX appears in the CosIng inventory

The CosIng inventory lists MADROX as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

MADROX is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

MADROX is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, MADROX carries the following function designation(s):

PERFUMING

CAS 37514-30-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for MADROX

This page reproduces the CosIng inventory entry for MADROX from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research MADROX and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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