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CAS 27538-10-9 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 3987902/03/2011

2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE

2-Ethyl-4-hydroxy-5-methylfuran-3(2H)-one

2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 27538-10-9

CAS 27538-10-9PubChem CID 33931

Homofuraneol

2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone is a member of the class of furans that is furan-3(2H)-one carrying additional ethyl, hydroxy and methyl substituents at positions 2, 4 and 5 respectively. A key aroma compound in soy sauce and fish sauce. It has a role as a Saccharomyces cerevisiae metabolite. It is a member of furans, an enol and a cyclic ketone. — ChEBI

IUPAC name: 2-ethyl-4-hydroxy-5-methylfuran-3-one

Molecular formula: C7H10O3
Molecular weight: 142.15 g/mol
Exact mass: 142.062994177 Da
XLogP3: 1.2
Topological polar surface area: 46.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

2-Ethyl-4-hydroxy-5-methyl-3(2H)-furanone3(2H)-FURANONE, 2-ETHYL-4-HYDROXY-5-METHYL-CHEBI:137995FEMA NO. 3623, 2-ETHYL-RefChem:4718182-Ethyl-4-hydroxy-5-methylfuran-3(2H)-oneEthyl furaneolHomofureanol

16 more reported names

4-Hydroxy-2-ethyl-5-methyl-3(2H)-furanoneHEMFVRF4YF0C3X2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone (homofuraneol)CCRIS 6903EINECS 248-514-6UNII-VRF4YF0C3XBRN 16174494-Hydroxy-2-ethyl-5-methyl-3-furanone2-ethyl-4-hydroxy-5-methyl-2,3-dihydrofuran-3-oneHOMOFURANEOL, 2-ETHYL-CS-W0143722-ethyl-4-hydroxy-5-methyl-furan-3-oneE04282-METHYL-3-HYDROXY-5-ETHYLFURAN-4-ONE2-METHYL-5-ETHYL-4,5-DIHYDROFURAN-3-OL-4-ONE

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:137995
EPA DTXSID:DTXSID40885393
PubMed:17636940

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for 2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE

INCI name

2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE

Description

2-Ethyl-4-hydroxy-5-methylfuran-3(2H)-one

Record provenance

Inventory reference: 39879
Imported identity: 2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE
Source update: 02/03/2011

European Commission CosIng source notes

Annex records for 2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE

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Key data

CAS

27538-10-9

248-514-6

Restriction

—

Function

PERFUMING: Used for perfume and aromatic raw materials.

Ingredients with overlapping formulation functions

2-ETHYL-2-(3-METHYLBUT-2-ENYL)HEX-3-ENOLPERFUMING

2-ETHYL-3,(5 OR 6)-DIMETHYLPYRAZINEPERFUMING

2-ETHYL-3,5-DIMETHYLPYRAZINEPERFUMING

2-ETHYL-3-METHYLPYRAZINEPERFUMING

2-ETHYL-5-METHOXY-BICYCLOHEPTANEPERFUMING

2-ETHYLBUTANOLPERFUMING

2-ETHYLBUTYL CYCLOPENT-1-ENEACETATEPERFUMING

2-ETHYLBUTYL CYCLOPENT-2-ENEACETATEPERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How 2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE appears in the CosIng inventory

The CosIng inventory lists 2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, 2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE carries the following function designation(s):

PERFUMING

CAS 27538-10-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for 2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE

This page reproduces the CosIng inventory entry for 2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research 2-ETHYL-4-HYDROXY-5-METHYLFURAN-3(2H)-ONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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