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InventoryRef 3797115/10/2010

SODIUM MONOFLUOROPHOSPHATE

Disodium fluorophosphate

SODIUM MONOFLUOROPHOSPHATE is linked to 1 EU annex record on this page. Inventory note: III/27.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Restricted entry found
Open this evidence		1English and EU languages
Great BritainEvidence linked
Restricted
Open this evidence		1English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Restricted
Open this evidence		2English
ASEANEvidence linked
Restricted
Open this evidence		1English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaEvidence linked
Restricted
Open this evidence		1English and Hindi
Saudi ArabiaEvidence linked
Restricted
Open this evidence		1Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 10163-15-2
CAS 10163-15-2CAS 7631-97-2PubChem CID 24266

Sodium Monofluorophosphate

Sodium fluorophosphate, commonly abbreviated MFP, is an inorganic compound with the chemical formula Na2PO3F. Typical for a salt, MFP is odourless, colourless, and water-soluble. This salt is an ingredient in toothpastes. It has a role as an antibacterial agent. It is an inorganic phosphate and an inorganic sodium salt. — ChEBI

IUPAC name
disodium;fluoro-dioxido-oxo-lambda5-phosphane
Molecular formula
FNa2O3P
Molecular weight
143.950 g/mol
Exact mass
143.93644758 Da
Topological polar surface area
63.2 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
3
Defined stereocentres
0

Also known as

Phosphorofluoridic acid, disodium saltExtra-Strength AimC810JCZ56QNSC-248bridentsmilecareRegularRembrandt
16 more reported names
SaliveaBarbieOrazenPriyalSparkleFreshMyntSmilepurple toothSmartMouthAGToothpasteCloveden ToothDeCureFinefra SilverGlancure ToothHello WhiteningKroger CompanyNatures Promise
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:86431

sodium fluorophosphate

Sodium fluorophosphate, commonly abbreviated MFP, is an inorganic compound with the chemical formula Na2PO3F. Typical for a salt, MFP is odourless, colourless, and water-soluble. This salt is an ingredient in toothpastes.

Formula
FO3P.2Na
Average mass
143.949 g/mol
Monoisotopic mass
143.93645 Da
Formal charge
0
  • inorganic sodium salt — is a (CHEBI:38702)
  • inorganic phosphate — is a (CHEBI:24838)
  • antibacterial agent — has role (CHEBI:33282)
  • antibacterial agent — has role (CHEBI:33282)
  • inorganic sodium salt — is a (CHEBI:38702)
  • inorganic phosphate — is a (CHEBI:24838)
Additional curated names
disodium phosphorofluoridatedisodium fluorophosphatedisodium monofluorophosphateNSC-248Phosphorofluoridic acid, disodium saltSodium fluorophosphatesodium monofluorophosphateSodium phosphorofluoridate
Cross-references from this source

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2015-07-24. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match24266

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 1.4% (1 of 72) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (91.7%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (11.1%): Causes skin irritation [Warning Skin corrosion/irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264, P270, P280, P301+P317, P302+P352, P321, P330, P332+P317, P362+P364, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 72 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 1 of 72 reports by companies.; There are 4 notifications provided by 71 of 72 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]; H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]; H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]; H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 8 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for SODIUM MONOFLUOROPHOSPHATE

INCI name

SODIUM MONOFLUOROPHOSPHATE

INN name

sodium monofluorophosphate

Description

Disodium fluorophosphate

Record provenance

Inventory reference
37971
Imported identity
SODIUM MONOFLUOROPHOSPHATE
Source update
15/10/2010
European Commission CosIng source notes

Key data

CAS
10163-15-2 / 7631-97-2
EC
233-433-0 / 231-552-2
Restriction
III/27
Function
ANTIPLAQUE
Helping protect against plaque.
ORAL CARE
Providing cosmetic effects to the oral cavity, e.g. cleansing, deodorising, protecting.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#26823 · SODIUM MONOFLUOROPHOSPHATE

Ingredients with overlapping formulation functions

SODIUM FLUORIDEANTIPLAQUE, ORAL CARE
SODIUM FLUOROSILICATEANTIPLAQUE, ORAL CARE
SODIUM GLYCEROPHOSPHATEANTIPLAQUE, ORAL CARE
SODIUM HYDROGENATED HONEY OCTENYLSUCCINATEANTIPLAQUE, CLEANSING, EMULSION STABILISING, HUMECTANT, SKIN CONDITIONING, SURFACTANT - CLEANSING, …
STANNOUS FLUORIDEANTIPLAQUE, ORAL CARE
STANNOUS PYROPHOSPHATEANTIPLAQUE, ORAL CARE, SOOTHING
STREPTOCOCCUS ORALISANTIPLAQUE, ORAL CARE, SKIN CONDITIONING
TETRAPEPTIDE-61ANTIOXIDANT, ANTIPLAQUE, HAIR CONDITIONING, SKIN CONDITIONING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How SODIUM MONOFLUOROPHOSPHATE appears in the CosIng inventory

The CosIng inventory lists SODIUM MONOFLUOROPHOSPHATE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SODIUM MONOFLUOROPHOSPHATE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SODIUM MONOFLUOROPHOSPHATE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for SODIUM MONOFLUOROPHOSPHATE reads: "III/27". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, SODIUM MONOFLUOROPHOSPHATE carries the following function designation(s):

CAS 10163-15-2 / 7631-97-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for SODIUM MONOFLUOROPHOSPHATE

This page combines the CosIng inventory entry for SODIUM MONOFLUOROPHOSPHATE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research SODIUM MONOFLUOROPHOSPHATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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