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InventoryRef 3748228/07/2020

RETINYL PALMITATE

Retinol, hexadecanoate

RETINYL PALMITATE is linked to 1 EU annex record on this page.

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Restricted entry found
Open this evidence
1English and EU languages
Great BritainSource mapped
Official source mapped; ingredient rule not imported
0English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandSource mapped
Official source mapped; ingredient rule not imported
0English
ASEANSource mapped
Official source mapped; ingredient rule not imported
0English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaSource mapped
Official source mapped; ingredient rule not imported
0Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 79-81-2
CAS 79-81-2PubChem CID 5280531

Retinol Palmitate

All-trans-retinyl palmitate is an all-trans-retinyl ester obtained by formal condensation of the carboxy group of palmitic (hexadecanoic acid) with the hydroxy group of all-trans-retinol. It is used in cosmetic products to treat various skin disorders such as acne, skin aging, wrinkles, dark spots, and also protect against psoriasis. It has a role as an antioxidant, a human xenobiotic metabolite and an Escherichia coli metabolite. It is a retinyl palmitate and an all-trans-retinyl ester. It is functionally related to an all-trans-retinol. ChEBI

IUPAC name
[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] hexadecanoate
Molecular formula
C36H60O2
Molecular weight
524.9 g/mol
Exact mass
524.45933115 Da
XLogP3
13.6
Topological polar surface area
26.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

retinyl palmitateVITAMIN A PALMITATERetinol, hexadecanoateall-trans-Retinyl palmitateArovitOptovit-ARetinyl hexadecanoateVitamin A Solubilized
16 more reported names
1D1K0N0VVCNSC-758478Retinol, palmitate, all-transAll-(e)-retinol palmitateCHEBI:17616Vitamin a palmitate (solubilized)Retinol Hexadecanoate((2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl) hexadecanoate(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl palmitatepalmitate-1-14cRetinol-15-3HRefChem:56213Retinyl-10,11-14C2CHEBI:15040201-228-5Afaxin
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for RETINYL PALMITATE

INCI name

RETINYL PALMITATE

Description

Retinol, hexadecanoate

Record provenance

Inventory reference
37482
Imported identity
RETINYL PALMITATE
Source update
28/07/2020
European Commission CosIng source notes

Key data

Restriction
Function
SKIN CONDITIONING
Maintaining the skin in good condition.
SKIN CONDITIONING - MISCELLANEOUS
Enhancing the appearance of dry and/or damaged skin by reducing flaking and restoring suppleness.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How RETINYL PALMITATE appears in the CosIng inventory

The CosIng inventory lists RETINYL PALMITATE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

RETINYL PALMITATE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

RETINYL PALMITATE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

According to the EU CosIng inventory, RETINYL PALMITATE carries the following function designation(s):

CAS 79-81-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for RETINYL PALMITATE

This page combines the CosIng inventory entry for RETINYL PALMITATE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research RETINYL PALMITATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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