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InventoryRef 3535415/10/2010

METHYLSILANOL PCA

L-Proline, 5-oxo-, dihydroxymethylsilyl ester

METHYLSILANOL PCA is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 105883-41-8
CAS 105883-41-8PubChem CID 72941639

Methylsilanol PCA

IUPAC name
[dihydroxy(methyl)silyl] (2S)-5-oxopyrrolidine-2-carboxylate
Molecular formula
C6H11NO5Si
Molecular weight
205.24 g/mol
Exact mass
205.04064899 Da
Topological polar surface area
95.9 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
5
Covalent units
1
Defined stereocentres
1

Also known as

Methylsilanol PCA [INCI]L-Proline, 5-oxo-, dihydroxymethylsilyl esterUNII-837430510VDIHYDROXYMETHYLSILYL L-PYROGLUTAMATERefChem:158314VOPVRRNGCBEXNL-BYPYZUCNSA-NDihydroxy(methyl)silyl 5-oxo-L-prolinate
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match72941639

Attributed physical-property, hazard, environmental and use annotations.

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBINo exact record2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for METHYLSILANOL PCA

INCI name

METHYLSILANOL PCA

Description

L-Proline, 5-oxo-, dihydroxymethylsilyl ester

Record provenance

Inventory reference
35354
Imported identity
METHYLSILANOL PCA
Source update
15/10/2010
European Commission CosIng source notes

Key data

EC
Restriction
Function
HUMECTANT
Retaining and/or preserving the moisture in a product during use.
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How METHYLSILANOL PCA appears in the CosIng inventory

The CosIng inventory lists METHYLSILANOL PCA as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

METHYLSILANOL PCA is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

METHYLSILANOL PCA is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, METHYLSILANOL PCA carries the following function designation(s):

CAS 105883-41-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for METHYLSILANOL PCA

This page reproduces the CosIng inventory entry for METHYLSILANOL PCA from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research METHYLSILANOL PCA and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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