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InventoryRef 3483715/10/2010

LACTULOSE

D-Fructose, 4-0-.beta.-D-galactopyranosyl-

LACTULOSE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 4618-18-2
CAS 4618-18-2PubChem CID 11333

Lactulose

Lactulose is a synthetic galactosylfructose disaccharide used in the treatment of constipation and hepatic encephalopathy. It has a role as a laxative and a gastrointestinal drug. ChEBI

IUPAC name
(2S,3R,4S,5R,6R)-2-[(2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
Molecular formula
C12H22O11
Molecular weight
342.30 g/mol
Exact mass
342.11621151 Da
XLogP3
-4.3
Topological polar surface area
190.0 Ų
Hydrogen-bond donors
8
Hydrogen-bond acceptors
11
Covalent units
1
Defined stereocentres
9

Also known as

D-LactuloseBifiteralCephulacChronulacConstilacLactulosaAcilacCholac
16 more reported names
ConstuloseLactulosumEnuloseGenerlacHeptalacLaxilosePortalacKristaloseLattulosio4-O-beta-D-Galactopyranosyl-D-fructoseLactulose jp174-galactosyl fructose4-O-beta-D-Galactopyranosyl-D-fructofuranoseNSC-7570829U7D5QH5AED-Fructose, 4-O-beta-D-galactopyranosyl-
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for LACTULOSE

INCI name

LACTULOSE

Description

D-Fructose, 4-0-.beta.-D-galactopyranosyl-

Record provenance

Inventory reference
34837
Imported identity
LACTULOSE
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
Function
HUMECTANT
Retaining and/or preserving the moisture in a product during use.
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How LACTULOSE appears in the CosIng inventory

The CosIng inventory lists LACTULOSE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

LACTULOSE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

LACTULOSE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, LACTULOSE carries the following function designation(s):

CAS 4618-18-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for LACTULOSE

This page reproduces the CosIng inventory entry for LACTULOSE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research LACTULOSE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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