KOJIC ACID
5-Hydroxy-2-hydroxymethyl-4-pyrone
KOJIC ACID is linked to 1 EU annex record on this page.
Regulatory evidence by market
This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.
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| Market | Evidence status | Records | Source language |
|---|---|---|---|
| European Union | Evidence linked Restricted entry found Open this evidence | 1 | English and EU languages |
| Great Britain | Evidence linked Restricted Open this evidence | 1 | English |
| Canada | Source mapped Official source mapped; ingredient rule not imported | 0 | English and French |
| New Zealand | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| ASEAN | Evidence linked Restricted Open this evidence | 1 | English and national languages |
| China | Source mapped Official source mapped; ingredient rule not imported | 0 | Chinese with selected English material |
| Japan | Source mapped Official source mapped; ingredient rule not imported | 0 | Japanese; official English translation available |
| South Korea | Source mapped Official source mapped; ingredient rule not imported | 0 | Korean with some English names |
| United States | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Australia | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Brazil | Source mapped Official source mapped; ingredient rule not imported | 0 | Portuguese with INCI crosswalks |
| India | Source mapped Official source mapped; ingredient rule not imported | 0 | English and Hindi |
| Saudi Arabia | Evidence linked Restricted Open this evidence | 1 | Arabic and English |
Chemical identity and properties
Kojic Acid
Kojic acid is a pyranone that is 4H-pyran substituted by a hydroxy group at position 5, a hydroxymethyl group at position 2 and an oxo group at position 4. It has been isolated from the fungus Aspergillus oryzae. It has a role as an EC 1.14.18.1 (tyrosinase) inhibitor, a NF-kappaB inhibitor, an Aspergillus metabolite, a skin lightening agent, an EC 1.10.3.1 (catechol oxidase) inhibitor, an EC 1.10.3.2 (laccase) inhibitor, an EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor and an EC 1.4.3.3 (D-amino-acid oxidase) inhibitor. It is a member of 4-pyranones, a primary alcohol and an enol. It derives from a hydride of a 4H-pyran. — ChEBI
- IUPAC name
- 5-hydroxy-2-(hydroxymethyl)pyran-4-one
- Molecular formula
- C6H6O4
- Molecular weight
- 142.11 g/mol
- Exact mass
- 142.02660867 Da
- XLogP3
- -0.9
- Topological polar surface area
- 66.8 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 4
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:43572
- ChEMBL:CHEMBL287556
- EPA DTXSID:DTXSID2040236
- PubMed:23353126
- PubMed:23091364
- PubMed:23089353
- PubMed:23063404
- PubMed:23054709
- PubMed:23016291
- PubMed:23007519
- PubMed:22952594
- PubMed:22939001
- PubMed:22926028
- PubMed:22909023
- PubMed:22905751
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for KOJIC ACID
INCI name
KOJIC ACID
Description
5-Hydroxy-2-hydroxymethyl-4-pyrone
Record provenance
- Inventory reference
- 34801
- Imported identity
- KOJIC ACID
- Source update
- 15/11/2016
Annex records for KOJIC ACID
Key data
- ANTIOXIDANT
- Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How KOJIC ACID appears in the CosIng inventory
The CosIng inventory lists KOJIC ACID as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.
KOJIC ACID is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for KOJIC ACID
This page combines the CosIng inventory entry for KOJIC ACID with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.
Use this inventory page to research KOJIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
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