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InventoryRef 3456630/07/2020

IMIDAZOLE

1H-Imidazole

IMIDAZOLE is linked to 1 EU annex record on this page. Inventory note: II/1589.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Prohibited entry found
Open this evidence		1English and EU languages
Great BritainEvidence linked
Prohibited
Open this evidence		1English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Prohibited
Open this evidence		1English
ASEANEvidence linked
Prohibited
Open this evidence		1English and national languages
ChinaEvidence linked
Prohibited
Open this evidence		1Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaEvidence linked
Prohibited
Open this evidence		1English and Hindi
Saudi ArabiaEvidence linked
Prohibited
Open this evidence		1Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 288-32-4
CAS 288-32-4PubChem CID 795

Imidazole

1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. — ChEBI

IUPAC name
1H-imidazole
Molecular formula
C3H4N2
Molecular weight
68.08 g/mol
Exact mass
68.037448136 Da
XLogP3
-0.1
Topological polar surface area
28.7 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
0

Also known as

GlyoxalineImidazolIminazoleMiazole1,3-DiazoleImutexGlyoxalin1,3-Diaza-2,4-cyclopentadiene
16 more reported names
Pyrro(b)monazoleGlioksalFormamidine, N,N'-vinylene-Pyrro[b]monazoleMethanimidamide, N,N'-1,2-ethenediyl-N,N'-vinyleneformamidine7GBN705NH1N,N'-1,2-ethenediylmethanimidamideNSC-60522CHEBI:16069RefChem:5902CHEBI:14434206-019-2USAF EK-4733Glioksal [Polish]IMD
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for IMIDAZOLE

INCI name

IMIDAZOLE

Description

1H-Imidazole

Record provenance

Inventory reference
34566
Imported identity
IMIDAZOLE
Source update
30/07/2020
European Commission CosIng source notes
Annex II Restriction reference
Entry 1589

Imidazole

CAS: 288-32-4
EC: 206-019-2

Key data

CAS
288-32-4
EC
206-019-2
Restriction
II/1589
Function
BUFFERING
Stabilising the pH of an aqueous medium in a narrow range even if an acid or base is added. Altering and/or maintaining a cosmetic product's pH at the desired level.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#13506 · IMIDAZOLE

Ingredients with overlapping formulation functions

HYDROBROMIC ACIDBUFFERING
HYDROCHLORIC ACIDBUFFERING
HYDROXYECTOINBUFFERING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT
HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACIDBUFFERING
ISOBUTYRIC ACIDBUFFERING
ISOPROPANOLAMINEBUFFERING
ISOPROPYLAMINEBUFFERING
ITACONIC ACIDANTIMICROBIAL, BUFFERING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How IMIDAZOLE appears in the CosIng inventory

The CosIng inventory lists IMIDAZOLE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

IMIDAZOLE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

IMIDAZOLE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for IMIDAZOLE reads: "II/1589". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, IMIDAZOLE carries the following function designation(s):

CAS 288-32-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for IMIDAZOLE

This page combines the CosIng inventory entry for IMIDAZOLE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research IMIDAZOLE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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