What does the restriction note for HC YELLOW NO. 8 mean?

The restriction field for HC YELLOW NO. 8 reads: II/1304. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 66612-11-1?

CAS 66612-11-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains HC YELLOW NO. 8?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3422315/10/2010

HC YELLOW NO. 8

N-[6-[(2-chloro-4-hydroxyphenyl)imino]-4-methoxy-3-oxo-1,4-cyclohexadien-1-yl]acetamide

HC YELLOW NO. 8 is linked to 1 EU annex record on this page. Inventory note: II/1304.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 66612-11-1

CAS 66612-11-1PubChem CID 3017692

N-[6-[(2-Chloro-4-hydroxyphenyl)imino]-4-methoxy-3-oxo-1,4-cyclohexadien-1-YL]acetamide

IUPAC name: N-[2-[(2-chloro-4-oxocyclohexa-2,5-dien-1-ylidene)amino]-5-hydroxy-4-methoxyphenyl]acetamide

Molecular formula: C15H13ClN2O4
Molecular weight: 320.73 g/mol
Exact mass: 320.0563846 Da
XLogP3: 1.5
Topological polar surface area: 88.0 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 0

Also known as

HC Yellow no. 8F1NQ5U8325UNII-F1NQ5U8325N-(6-((2-Chloro-4-hydroxyphenyl)imino)-4-methoxy-3-oxo-1,4-cyclohexadien-1-yl)acetamideN-{2-[(2-CHLORO-4-OXOCYCLOHEXA-2,5-DIEN-1-YLIDENE)AMINO]-5-HYDROXY-4-METHOXYPHENYL}ACETAMIDEEINECS 266-424-5HC Yellow 8Yellow No. 8

8 more reported names

IMEXINE ILDNCKSSGISBCYQW-UHFFFAOYSA-NN-(6-((2-Chloro-4-hydroxyphenyl)imino)-4-methyoxy-3-oxo-1,4-cyclo- hexadien-1-yl)acetamideAcetamide, N-(6-((2-chloro-4-hydroxyphenyl)imino)-4-methyoxy-3-oxo-1,4-cyclo- hexadien-1-yl)-N-(2'-Chloro-4'-hydroxyphenyl)-3-acetylamino-6-methoxy-1,4-benzoq- uinoneimineN-(2'-CHLORO-4'-HYDROXYPHENYL)-3-ACETYLAMINO-6-METHOXY-1,4-BENZOQUINONEIMINEACETAMIDE, N-(6-((2-CHLORO-4-HYDROXYPHENYL)IMINO)-4-METHOXY-3-OXO-1,4-CYCLOHEXADIEN-1-YL)-N-{(6E)-6-[(2-Chloro-4-hydroxyphenyl)imino]-4-methoxy-3-oxocyclohexa-1,4-dien-1-yl}acetamide

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID60867237
EPA DTXSID:DTXSID70879806

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for HC YELLOW NO. 8

INCI name

HC YELLOW NO. 8

Description

N-[6-[(2-chloro-4-hydroxyphenyl)imino]-4-methoxy-3-oxo-1,4-cyclohexadien-1-yl]acetamide

Record provenance

Inventory reference: 34223
Imported identity: HC YELLOW NO. 8
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for HC YELLOW NO. 8

Annex II Restriction reference

Entry 1304

N-[6-[(2-Chloro-4-hydroxyphenyl)imino]-4-methoxy-3-oxo-1,4-cyclohexadien-1-yl]acetamide (HC Yellow …

CAS: 66612-11-1

EC: 266-424-5

Key data

CAS

66612-11-1

266-424-5

Restriction

II/1304

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#11629 · HC YELLOW NO. 8

Records sharing a CAS or EC identity

HYDROXYPHENYL DIHYDROXYBENZAMIDE

Ingredients with overlapping formulation functions

HC YELLOW NO. 4HAIR DYEING

HC YELLOW NO. 5HAIR DYEING

HC YELLOW NO. 6HAIR DYEING

HC YELLOW NO. 7HAIR DYEING

HC YELLOW NO. 9HAIR DYEING

HENNABULKING, HAIR DYEING, SKIN CONDITIONING

HYDROXYANTHRAQUINONEAMINOPROPYL METHYL MORPHOLINIUM METHOSULFATEHAIR DYEING

HYDROXYBENZOMORPHOLINEHAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How HC YELLOW NO. 8 appears in the CosIng inventory

The CosIng inventory lists HC YELLOW NO. 8 as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HC YELLOW NO. 8 is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HC YELLOW NO. 8 appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for HC YELLOW NO. 8 reads: "II/1304". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, HC YELLOW NO. 8 carries the following function designation(s):

HAIR DYEING

CAS 66612-11-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for HC YELLOW NO. 8

This page combines the CosIng inventory entry for HC YELLOW NO. 8 with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research HC YELLOW NO. 8 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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