Is GLUTAMIC ACID safe to use in EU cosmetics?

GLUTAMIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 56-86-0?

CAS 56-86-0 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3401715/10/2010

GLUTAMIC ACID

(S)-2-Aminopentanedioic acid

GLUTAMIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 56-86-0

CAS 56-86-0PubChem CID 33032

L-Glutamic Acid

L-glutamic acid is an optically active form of glutamic acid having L-configuration. It has a role as a ferroptosis inducer, a neurotransmitter, a micronutrient, a nutraceutical, a mouse metabolite and an Escherichia coli metabolite. It is a L-alpha-amino acid, a glutamic acid, a glutamine family amino acid and a proteinogenic amino acid. It is a conjugate acid of a L-glutamate(1-). It is an enantiomer of a D-glutamic acid. — ChEBI

IUPAC name: (2S)-2-aminopentanedioic acid

Molecular formula: C5H9NO4
Molecular weight: 147.13 g/mol
Exact mass: 147.05315777 Da
XLogP3: -3.7
Topological polar surface area: 101.0 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 1

Also known as

GLUTAMIC ACIDL-glutamate(S)-2-Aminopentanedioic acidGlutamidexGlutatonL-Glutaminic acidAciglutGlutaminol

16 more reported names

glutacidGlutamicol(S)-Glutamic acidglutaminic acidL-gluL-(+)-glutamic acidGlutamic acid, L-Acido glutamicoAcide glutamiquealpha-aminoglutaric acidAcidum glutamicum(S)-(+)-Glutamic acidL-alpha-Aminoglutaric acidAcidum glutaminicumglutL-2-Aminoglutaric acid

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:16015
ChEBI:CHEBI:53374
ChEMBL:CHEMBL575060
EPA DTXSID:DTXSID5020659
PubMed:29968805
PubMed:25026896
PubMed:23118969
PubMed:23118715
PubMed:23118600
PubMed:23118561
PubMed:23115559
PubMed:23115168
PubMed:23113272
PubMed:23113266
PubMed:23113265
PubMed:23112327

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for GLUTAMIC ACID

INCI name

GLUTAMIC ACID

INN name

glumatic acid

Description

(S)-2-Aminopentanedioic acid

Record provenance

Inventory reference: 34017
Imported identity: GLUTAMIC ACID
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for GLUTAMIC ACID

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Key data

CAS

56-86-0

200-293-7

Restriction

—

Function

ANTISTATIC: Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
HUMECTANT: Retaining and/or preserving the moisture in a product during use.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#11036 · GLUTAMIC ACID

Ingredients with overlapping formulation functions

GLUCOSAMINEANTISTATIC, HAIR CONDITIONING

GLUCOSAMINE HCLANTISTATIC, HAIR CONDITIONING

GLUCOSE GLUTAMATEANTISTATIC, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING

GLUCOSYL NARINGINANTISTATIC, HUMECTANT, SKIN PROTECTING

GLUTAMINEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

GLYCERYL DISTEARATEANTISTATIC, SKIN CONDITIONING - EMOLLIENT

GLYCERYL LANOLATEANTISTATIC, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING

GLYCINEANTISTATIC, BUFFERING, HAIR CONDITIONING, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How GLUTAMIC ACID appears in the CosIng inventory

The CosIng inventory lists GLUTAMIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

GLUTAMIC ACID is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

GLUTAMIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, GLUTAMIC ACID carries the following function designation(s):

CAS 56-86-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for GLUTAMIC ACID

This page reproduces the CosIng inventory entry for GLUTAMIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research GLUTAMIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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