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CAS 32449-92-6 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 3401615/10/2010

GLUCURONOLACTONE

D-Glucuronic acid, .gamma.-lactone

GLUCURONOLACTONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 32449-92-6

CAS 32449-92-6PubChem CID 92283

Glucuronolactone

D-glucurono-6,3-lactone is a glucuronolactone. It has a role as a mouse metabolite and a human metabolite. It is functionally related to a D-glucuronic acid. — ChEBI

IUPAC name: (2R)-2-[(2S,3R,4S)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetaldehyde

Molecular formula: C6H8O6
Molecular weight: 176.12 g/mol
Exact mass: 176.03208797 Da
XLogP3: -1.8
Topological polar surface area: 104.0 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 6
Covalent units: 1
Defined stereocentres: 4

Also known as

D-Glucurono-6,3-lactoneD-GlucuronolactoneGLUCUROLACTONED-GlucuroneGlucuroneD-Glucuronic acid lactoneGlucuronosanGuronsan

16 more reported names

GlucoxyGlucurolactonaGlucurolactonumGlucuronolattoneDicuroneD-Glucofuranuronic acid, gamma-lactoneD-Glucuronic acid, gamma-lactoneGluronsanXE4Y3016M9CHEBI:18268gamma-Lactone of D-glucofuranuronic acidNSC-656NSC656glucuronic acid, gamma-lactone(2R)-2-((2S,3R,4S)-3,4-dihydroxy-5-oxooxolan-2-yl)-2-hydroxyacetaldehydeRefChem:663158

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:18268
PubMed:23056435

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for GLUCURONOLACTONE

INCI name

GLUCURONOLACTONE

Description

D-Glucuronic acid, .gamma.-lactone

Record provenance

Inventory reference: 34016
Imported identity: GLUCURONOLACTONE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for GLUCURONOLACTONE

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Key data

CAS

32449-92-6

251-053-3

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#11034 · GLUCURONOLACTONE

Ingredients with overlapping formulation functions

GLUCOSE GLUTAMATEANTISTATIC, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING

GLUCOSYL CERAMIDESKIN CONDITIONING

GLUCOSYL HESPERIDINHUMECTANT, SKIN CONDITIONING

GLUCOSYL RESVERATROLANTIOXIDANT, ANTIPLAQUE, HUMECTANT, SKIN CONDITIONING

GLUTAMINEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

GLUTAMOYL AMINOGUANIDINESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

GLUTAMYL HYDROXYPHENYLHYDRAZIDESKIN CONDITIONING

GLUTAMYL METHYLSULFONYL FLUOROPHENYLHYDRAZIDEANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How GLUCURONOLACTONE appears in the CosIng inventory

The CosIng inventory lists GLUCURONOLACTONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

GLUCURONOLACTONE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

GLUCURONOLACTONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, GLUCURONOLACTONE carries the following function designation(s):

SKIN CONDITIONING

CAS 32449-92-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for GLUCURONOLACTONE

This page reproduces the CosIng inventory entry for GLUCURONOLACTONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research GLUCURONOLACTONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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