InventoryRef 3393516/05/2019
FERULIC ACID
4-Hydroxy-3-methoxycinnamic acid
FERULIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.
Swipe or scroll horizontally to see every column.
| Market | Evidence status | Records | Source language |
|---|---|---|---|
| European Union | Source mapped Inventory entry; no linked annex rule | 0 | English and EU languages |
| Great Britain | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Canada | Source mapped Official source mapped; ingredient rule not imported | 0 | English and French |
| New Zealand | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| ASEAN | Source mapped Official source mapped; ingredient rule not imported | 0 | English and national languages |
| China | Source mapped Official source mapped; ingredient rule not imported | 0 | Chinese with selected English material |
| Japan | Evidence linked Restricted Open this evidence | 1 | Japanese; official English translation available |
| South Korea | Source mapped Official source mapped; ingredient rule not imported | 0 | Korean with some English names |
| United States | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Australia | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Brazil | Source mapped Official source mapped; ingredient rule not imported | 0 | Portuguese with INCI crosswalks |
| India | Source mapped Official source mapped; ingredient rule not imported | 0 | English and Hindi |
| Saudi Arabia | Source mapped Official source mapped; ingredient rule not imported | 0 | Arabic and English |
Chemical identity and properties
CAS 1135-24-6PubChem CID 445858
Ferulic Acid
Ferulic acid is a member of the class of ferulic acids that is cinnamic acid substituted by a methoxy and a hydroxy group at positions 3 and 4 of the phenyl ring. It has a role as an antioxidant, a neuroprotective agent and a plant metabolite. — ChEBI
- IUPAC name
- (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
- Molecular formula
- C10H10O4
- Molecular weight
- 194.18 g/mol
- Exact mass
- 194.05790880 Da
- XLogP3
- 1.5
- Topological polar surface area
- 66.8 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 4
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
4-Hydroxy-3-methoxycinnamic acid3-(4-Hydroxy-3-methoxyphenyl)acrylic acidConiferic acid3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid3-methoxy-4-hydroxycinnamic acid2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-AVM951ZWSTNSC-2821
16 more reported names
NSC-51986NSC-674320CHEBI:17620ferulic acid, (E)-RefChem:5829ferulic acid, monosodium salt214-490-0805-535-0trans-Ferulic Acid537-98-4(E)-Ferulic acidtrans-4-Hydroxy-3-methoxycinnamic acid(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid(E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acidferulaic acidFerulic acid, trans-
External database identifiers
- ChEBI:CHEBI:17620
- ChEBI:CHEBI:193350
- ChEMBL:CHEMBL32749
- EPA DTXSID:DTXSID70892035
- PubMed:24358168
- PubMed:23800587
- PubMed:21763500
- PubMed:18952420
- PubMed:15229801
- PubMed:12076751
- PubMed:9561563
Evidence from additional scientific databases
NIH PubChem PUG-View
Exact identifier match445858
Attributed physical-property, hazard, environmental and use annotations.
- Dissociation Constants: pKa = 4.58 Source: Hazardous Substances Data Bank (HSDB)
- LogP: log Kow = 1.51 Source: Hazardous Substances Data Bank (HSDB)
- LogP: 1.51 Source: Human Metabolome Database (HMDB)
- Melting Point: 168 - 171 °C Source: Human Metabolome Database (HMDB)
- Physical Description: cis-Form is a yellow liquid; trans-Form is a solid; [Merck Index] trans-Isomer: Tan powder; [Alfa Aesar MSDS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: Tan powder; [Alfa Aesar MSDS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: Solid Source: Human Metabolome Database (HMDB)
- Vapor Pressure: 0.00000269 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Note: This chemical does not meet GHS hazard criteria for 2.4% (8 of 329) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H315 (97.6%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (97.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (97.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 329 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 8 of 329 reports by companies.; There are 7 notifications provided by 321 of 329 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Note: This chemical does not meet GHS hazard criteria for 1% (1 of 105) of reports. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H315 (99%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (99%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (98.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 105 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 1 of 105 reports by companies.; There are 9 notifications provided by 104 of 105 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P261, P272, P280, P302+P352, P321, P333+P317, P362+P364, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. Source: European Chemicals Agency (ECHA)
- Environmental Bioconcentration: An estimated BCF of 3.2 was calculated in fish for ferulic acid, using a measured log Kow of 1.51 (1) and a regression-derived equation (2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organism is low(SRC), provided the compound is not metabolized by the organism(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 57(SRC), determined from a log Kow of 1.51(2) and a regression-derived equation(3), indicates that ferulic acid is expected to have high mobility in soil(SRC). The pKa of ferulic acid is 4.58(4), indicating that this compound will almost entirely exist in the anion form. In the environment, anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5). Volatilization of ferulic acid from moist soil surfaces is not expected to be an important fate process(SRC) given the anionic nature of ferulic acid in the environment. Ferulic acid is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 2.7X10-6 mm Hg(SRC), determined from a fragment constant method(6). Under neutral and acidic conditions in soil, ferulic acid is expected to undergo rapid aerobic biodegradation(7)(8). Under alkaline conditions in soil, ferulic acid is not expected to undergo rapid aerobic biodegradation(8). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 57(SRC), determined from a log Kow of 1.51(2) and a regression-derived equation(3), indicates that ferulic acid is not expected to adsorb to suspended solids and sediment(SRC). A pKa of 4.58(4) indicates ferulic acid will exist almost entirely in the anion form at pH values of 5 to 9, and therefore volatilization from water surfaces/moist soil is not expected to be an important fate process(5). According to a classification scheme(6), an estimated BCF of 3.2(SRC), from its log Kow of 1.51(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Ferulic acid is expected to biodegrade rapidly in water under anaerobic conditions(8). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), ferulic acid, which has a an estimated vapor pressure of 2.7X10-6 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), will exist in both the vapor and particulate phases. Vapor-phase ferulic acid is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 8 hours(SRC), calculated from its rate constant of 4.8X10-11 cu cm/molecule-sec at 25 °C(SRC), derived using a structure estimation method(3). Particulate-phase ferulic acid may be removed from the air by wet or dry deposition(SRC). Ferulic acid contains a chromophore that absorbs light at wavelengths >290 nm(4) and therefore may be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Sources/Uses: Found in small amounts in many plants; Used as a food preservative; [Merck Index] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Sources/Uses: Widely distributed in plants; [Alfa Aesar MSDS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: Food preservative Source: Hazardous Substances Data Bank (HSDB)
- Uses: /Ferulic acid was one of several compounds identified in/ ... a survey of 624 commercially available supplements targeted towards bodybuilding athletes... Source: Hazardous Substances Data Bank (HSDB)
- Uses: Synthetic Polymer MALDI Matrix Compounds Source: NIST Synthetic Polymer MALDI Recipes Database
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for FERULIC ACID
INCI name
FERULIC ACID
Description
4-Hydroxy-3-methoxycinnamic acid
Record provenance
- Inventory reference
- 33935
- Imported identity
- FERULIC ACID
- Source update
- 16/05/2019
Annex records for FERULIC ACID
Key data
CAS
EC
Restriction
—
Function
- ANTIMICROBIAL
- Preventing and/or slowing down microbial growth.
- ANTIOXIDANT
- Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal
How FERULIC ACID appears in the CosIng inventory
The CosIng inventory lists FERULIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
FERULIC ACID is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
FERULIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.
According to the EU CosIng inventory, FERULIC ACID carries the following function designation(s):
CAS 1135-24-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.
Source note for FERULIC ACID
This page reproduces the CosIng inventory entry for FERULIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research FERULIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
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